Synthesis Of Hydroxyapatite Nanopowders Research Articles

Synthesis of hydroxyapatite nano powders by rapid gel combustion

Synthesis of hydroxyapatite nano powders by rapid gel combustion

Synthesis of hydroxyapatite nano powders by rapid gel combustion

In this study, we have executed a very detailed literature research on the synthesis of hydroxyapatite (HA), {Ca10(PO4)6(OH)2} nano powders. HA is a very important bioceramic material with excellent biocompatibility and bone bonding ability used in the medical field as bone substitute materials, because of its structural and compositional similarity to that of the mineral phase of hard tissue in human beings. HA nano powders (n-HAPs) in soft agglomerate form were synthesised by 'Rapid Gel Combustion' process. Synthesised n-HAPs were characterised by SEM, XRD and FTIR. The n-HAPs have white colour, spherical morphology consisting of micro and nano pores, crystallite size of 42.74 nm, very high specific surface area of 74.06 m2.g−1, Ca/P molar ratio of 1.65 and crystalline structure with characteristic HA peaks (JCPDF 9-432) without any secondary phases. FTIR spectra demonstrated the characteristic peaks of absorbed water, hydroxyl and Ca-phosphate.

Synthesis of hydroxyapatite nanopowders by sol-gel emulsion technique

Hydroxyapatite nanopowders were synthesized by a sol-gel emulsion technique by varying the concentration of a non-ionic surfactant in the organic phases (oil phase) of water-in-oil (w/o) emulsion. Calcium acetate dissolved in distilled water and phosphorous pentoxide dissolved in 2-butanol were used as starting precursors. The prepared sol was emulsified in a support solvent (cyclohexane) containing 2, 4 and 5 volume% of surfactant (Span 80), followed by the addition of triethylamine, for gelation. The gel powders thus obtained were calcined at different temperatures up to 750°C. Characterization was done using XRD, SEM and TEM. Pellets were made from the developed HAP powders and tested for its biocompatibility after their immersion in the simulated body fluid.

Synthesis of Hydroxyapatite Nanopowders via Sucrose‐Templated Sol–Gel Method

The present research describes synthesis of hydroxyapatite (HAp) nanopowders using a sol–gel route with calcium nitrate and ammonium hydrogen phosphate as calcium and phosphorous precursors, respectively. Sucrose is used as template material, and alumina is added as a dopant to study its effects on particle size and surface area. Synthesized powders are characterized using X‐ray diffractometry, BET surface‐area analysis, and transmission electron microscopy. Results show that alumina stabilizes the HAp crystalline phase. Average particle size of mesoporous HAp samples is between 30 and 50 nm with surface area of 51–60 m2/g.