Synthesis Of Epimer Research Articles

ChemInform Abstract: Synthesis of 5-Benzyl and 5-Benzyloxybenzyl-3′-azido-2′,3′- dideoxyuridine and Their Analogues as Potential Anti-AIDS Agents

5-Benzyl and 5-benzyloxybenzyl-substituted 3′-azido-2′,3′-dideoxyuridine, (8a and 8b), 3′-halogeno-2′,3′-dideoxyuridine, 9a, 9b, 10a, 10b, 11a and 11b, and 2′,3′-dideoxyuridine, 12a and 12b, of Scheme I were synthesized as potential anti AIDS agents. Synthesis of epimers of 8a and 8b, 5-benzyl- and 5-benzyloxybenzyl-1-(3′-azido-2′,3′-dideoxy-β-D-threo-pentafuranosyl)uracil, 15a and 15b, and 5-benzyl- and 5-benzyloxy-5′-azido-2′,5′-dideoxyuridine, 16a and 16b, shown in Scheme II, were also reported.

The synthesis and conformation of β-cyclodextrins functionalized with enantiomers of Boc-carnosine

The synthesis of epimers 6-deoxy-6-[ N- tert-butoxycarbony1-β-alanyl-( S)histidylamino]-β-cyclodextrin and 6-deoxy-6-[ N- tert-butoxycarbonyl-β-alanyl-( R)histidylamino]-β-cyclodextrin is reported. CD and NMR spectroscopy reveals that in aqueous solution these compounds are arranged in a ‘sleeping swan’ like conformation. H bonds between the NH of peptide bonds and the upper rim of CDs stabilize self-inclusion. The chirality of His influences the orientation of the self-included chain in the cavity, thus determining different properties for the two epimers.

ChemInform Abstract: The Substrate Specificity of the Enzyme Amyloglucosidase (AMG). Part 3. Synthesis of Epimers and Mono‐O‐methyl Ethers of Methyl β‐Maltoside.

ChemInform Abstract: The Substrate Specificity of the Enzyme Amyloglucosidase (AMG). Part 3. Synthesis of Epimers and Mono‐O‐methyl Ethers of Methyl β‐Maltoside.

The Substrate Specificity of the Enzyme Amyloglucosidase (AMG). Part III. Synthesis of Epimers and Mono-O-methyl Ethers of Methyl beta-Maltoside.

The Substrate Specificity of the Enzyme Amyloglucosidase (AMG). Part III. Synthesis of Epimers and Mono-O-methyl Ethers of Methyl beta-Maltoside.