Symptoms Of Dentin Hypersensitivity Research Articles

A novel treatment based on powder jet deposition technique for dentin hypersensitivity: a randomized controlled trial

BackgroundThis study aimed to evaluate the efficacy and safety of dentin hypersensitivity (DH) treatment using a newly developed device based on a powder jet deposition (PJD) technique that creates a hydroxyapatite (HAP) layer on the dentin surface, thereby alleviating the hypersensitivity. The effect of the PJD treatment was compared with that of conventional treatment using Teethmate Desensitizer (TMD; calcium-phosphate containing material with TTCP (Ca4(PO4)2O) and DCPA (CaHPO4)), which has been used clinically in Japan with well-confirmed effectiveness.Materials and methodsA randomized controlled trial was conducted including 35 patients who had symptoms of DH in two or more quadrants. Two test teeth were selected per patient (70 teeth in total) and randomly assigned to PJD or TMD treatment. The efficacy was evaluated using the improvement rate for air and scratch pain according to the scores obtained via visual analog scale 12 weeks after treatment. The safety assessment was performed focusing on gingival index (GI) and spontaneous pain. The t-test was used to analyze the non-inferiority of PJD treatment compared to TMD treatment.ResultsThe improvement rate of air pain was 69.0% for PJD and 69.7% for TMD. The improvement rate of scratch pain was 80.8% for PJD and 81.7% for TMD. Non-inferiority with a margin of 10% was not observed for both air and scratch pain. No change was observed in GI from baseline and the improvement rate of spontaneous pain for PJD was higher than that for TMD.ConclusionNon-inferiority of PJD to TMD treatment was not observed in this study; however, it was not statistically demonstrated, and the results were thus interpreted as inconclusive. PJD did improve the DH symptoms, as did TMD. PJD’s therapeutic effect was most likely attributable to the deposition of a HAP layer on the tooth surface, which would alleviate hypersensitivity for at least 12 weeks without causing severe adverse events.Trial registrationUMIN-CTR. ID: UMIN000025022. date: 02/12/2016.

Whitening Effects of a Novel Oral Care Gel with Biomimetic Hydroxyapatite: A 4-Week Observational Pilot Study.

The whitening effects of an oral care gel based on particulate microcrystalline hydroxyapatite, Ca5(PO4)3(OH), were tested in a 4-week observational pilot study. Patients were recruited from two dental practices in Germany. Participants were asked to complete a questionnaire regarding their personal perception of their tooth color and brightness as well as the level of dentin hypersensitivity at the baseline and after 4 weeks of twice daily use of an oral care gel with hydroxyapatite. Data of 25 patients with a mean age of 46 ± 16 years were analyzed. Various subjective whitening parameters showed a tendency to be improved after the 4-week use. Additionally, patients reported that symptoms of dentin hypersensitivity were significantly reduced (p < 0.05, 95% confidence interval (CI): (0.8; 2.4)), and the tooth surface was significantly smoother (p < 0.05, 95% CI: (0.54; 1.6)). In conclusion, microcrystalline hydroxyapatite is a promising whitening agent for oral care formulations and represents a biomimetic alternative to other whitening agents for daily dental care.

Ameloblastoma ex COC: An enigma to clinicians and Pathologists

Background and Aim: Dentin hypersensitivity (DH) is a common oral health problem affecting one or more teeth of many adult individuals globally. It is characterized by a sharp pain which arises from exposed dentin in response to an external stimulus, and cannot be explained by any other form of dental pathology. Several agents and treatment modalities have been used in the treatment of this condition. The present study was conducted to compare the efficacy of arginine calcium carbonate paste (Test group) versus potassium nitrate (Control group) in the treatment of dentinal hypersensitivity. Subjects and Methods: A total of 66 cases were randomly divided into two groups based on the toothpaste given: Test group - toothpaste containing 8% arginine and calcium carbonate, Control group - toothpaste containing 5% potassium nitrate. The patients’ DH scores for tactile stimuli was recorded on a visual analog scale and airblast stimuli was recorded on a Schiff Cold Air Sensitivity scale at baseline, immediately post scaling after application of desensitizing paste, 1 month after commencing the use of desensitizing paste, and 1 month following cessation of its use . Statistical Analysis: The data was analyzed using Independent t test (P < 0.05). Results: Both the toothpastes were effective in relieving dentinal hypersensitivity. However, toothpaste containing 8% arginine and calcium carbonate showed a better clinical response at the end of 2 months evaluation. Conclusions: The desensitizing paste containing 8% arginine and calcium carbonate showed instant and long lasting reduction in the symptoms of DH.

Comparative Evaluation of Desensitizing Efficacy of Dentifrice Containing 5% Fluoro Calcium Phosphosilicate versus 5% Calcium Sodium Phosphosilicate: A Randomized Controlled Clinical Trial.

Background:A considerable number of agents are effective in the treatment of dentin hypersensitivity (DH). The present 2 months' randomized clinical trial compared the desensitizing efficacy of dentifrice containing 5% fluoro calcium phosphosilicate versus 5% calcium sodium phosphosilicate in participants with sensitive teeth.Materials and Methods:A total of 60 participants above 18 years of age with a history of DH who displayed a visual analog scale (VAS) score of ≥ 4 to both subjective and thermal sensitivity in at least two teeth at the qualifying as well as baseline visit were considered eligible. Participants were randomly allocated to one of the following dentifrices: 5% fluoro calcium phosphosilicate; 5% calcium sodium phosphosilicate; and a standard dentifrice containing fluoride. Sensitivity scores (VAS) were measured at baseline, immediately after scaling and root planning, at 15, 30, and at 60 days.Results:A statistically significant reduction in symptoms for all treatment groups from baseline to 15, 30, and 60 days for both measures of sensitivity was observed. A significant reduction in DH with time for all the variables during the 8 weeks of the active phase of the study independent of treatment groups was noted. However, the fluoro calcium phosphosilicate group showed a higher degree of effectiveness in reducing DH, followed by calcium sodium phosphosilicate then standard fluoride dentifrices.Conclusion:Under the conditions of a clinical trial, the fluoro calcium phosphosilicate group showed a comparable reduction in the symptoms of DH.

Clinical effect of CEREC chairside on atypical ceramic inlay restoring class II cavity

Objective To evaluate the clinical effect of CEREC chairside on atypical porcelain inlay restoring class Ⅱ cavity. Methods 30 patients that required re-treatment because of resin restoration failure and early posterior proximal caries were selected randomly. The original fillings, secondary carious tissues and undercut parts were removed. The clear and round edge lines were prepared. With Sirona CEREC Blocs, 35 atypical ceramic inlays were produced in accordance with CEREC AC CAD/CAM standard procedures. After clinical trial and modification, the inlays were bonded with 3M Veneer resin adhesive cement. Evaluation was done immediately and 3, 6, 12 and 24 months after restoration. Two senior prosthodontists did the evaluation according to the modified USPHS criteria. Results The evaluation results were all A when estimated immediately after restoration. None inlay falled off during the first two years. However, 3 inlay were found to be damaged when reviewed at the 24th month. There exsited two patients having mild symptoms of dentine hypersensitivity which appeared at the beginning and died out gradually. Generally speaking, more than 90% of inlay restorations had reached the USPHS criteria A. Color match and retention represented better effects. Conclusions CEREC atypical ceramic inlays can effectively restore Class Ⅱ cavity, short-term effect is good, but long-term effect still needs further observations. Key words: Ceramic inlay; Computer aided design/computer-aided manufacturing; CEREC

Clinical efficacy of four interventions in the reduction of dentinal hypersensitivity: A 2-month study.

Dentinal hypersensitivity is a relatively common problem experienced in clinical dental practice and is characterized by short, sharp pain in response to stimuli such as tactile, thermal, evaporative, osmotic, or chemical. Several agents and treatment modalities have been used in the treatment of this condition. This study was conducted to compare the efficacy of four commercially available toothpastes in the reduction of dentinal hypersensitivity (DH), based on the hypothesis that calcium sodium phosphosilicate (CSPS) group had a better efficacy of the four. This study design was a prospective, single-blind, randomized, parallel clinical design. A total of 160 cases (93 males and 67 females; aged 20-60 years) were randomly divided into four groups: Group 1 - toothpaste containing 5% potassium nitrate; Group 2 - toothpaste containing 5% CSPS (NovaMin); Group 3 - toothpaste containing 10% strontium chloride; and Group 4 - a herbal formulation. The patients' DH scores for tactile, thermal, and evaporative stimuli were recorded on a visual analog scale at baseline, 2 weeks, 1 month, and 2 months. The data were analyzed with Wilcoxon signed-rank test, Kruskal-Wallis test, and Mann-Whitney U-test (P < 0.05). The four desensitizing kinds of toothpaste containing different active agents were effective in relieving dentinal hypersensitivity. However, CSPS group showed a better clinical response at the end of 2 months. The CSPS group showed a better reduction in the symptoms of DH.

Comparison of efficacy of three commercially available dentifrices on dentinal hypersensitivity: a randomized clinical trial

Dentinal hypersensitivity has been defined as a short, sharp pain arising from exposed dentine as a result of various stimuli such as heat, cold, chemical, or osmotic, that cannot be ascribed to any other pathology. This study was conducted to assess the efficacy of three commercially available toothpastes in the reduction of dentinal hypersensitivity. A total of 149 subjects (72 males and 77 females; aged 20 to 60 years) were entered into the study and randomly divided into four groups: Group 1 - toothpaste containing 5% potassium nitrate; Group 2 - toothpaste containing 5% calcium sodium phosphosilicate with fused silica; Group 3 - toothpaste containing 3.85% amine fluoride; and Group 4 - a placebo toothpaste. After sensitivity scores for controlled air stimulus and cold water at baseline were recorded, subjects were given toothpastes and sensitivity scores were measured again at 2 weeks and 6 weeks. All groups showed a reduction in sensitivity scores at 2 weeks and 6 weeks. The calcium sodium phosphosilicate group was found to be significantly better compared to the other groups at the end of 6 weeks. The calcium sodium phosphosilicate group showed a better reduction in the symptoms of dentinal hypersensitivity.

Comparison of Clinical Efficacy of a Dentifrice Containing Calcium Sodium Phosphosilicate to a Dentifrice Containing Potassium Nitrate and to a Placebo on Dentinal Hypersensitivity: A Randomized Clinical Trial

A considerable number of agents are effective in the treatment of dentin hypersensitivity. This 6-week randomized clinical trial compares a dentifrice containing calcium sodium phosphosilicate to potassium nitrate and to a placebo. A total of 110 subjects (58 males and 52 females; aged 20 to 60 years) were entered into the study. The volunteers selected at baseline had a history of dentin hypersensitivity caused by gingival recession or cervical erosion. Patients were required to have at least two teeth with a visual analog scale score of > or =4 to be included in the study. After sensitivity scores for controlled air stimulus (evaporative stimulus) and cold water (thermal stimulus) at baseline were recorded, subjects were given toothpastes randomly, and sensitivity scores were measured again at 2- and 6-week follow-ups. All three groups showed reduction in sensitivity scores at 2 weeks and 6 weeks for air stimulus and cold water. The calcium sodium phosphosilicate group, however, was found to be significantly better in reducing the visual analog scale score compared to the potassium nitrate group and the placebo group at any time point for both measures of sensitivity. Under the conditions of a clinical trial, the calcium sodium phosphosilicate group showed comparable reduction in the symptoms of dentin hypersensitivity.