How ventilation corridors affect urban climate is attracting researchers' attention. Taking the inland Chinese city of Wuhan as an example, this paper first uses remote sensing image technology to evaluate the urban thermal environment. Additionally, based on the GIS/RS spatial analysis method, the ventilation corridors in the central urban area are identified and constructed. Finally, the mesoscale meteorological model WRF-UCM is used to simulate four cases with different corridor forms to explore the impact of different corridors on the climate environment in Wuhan during the summer. The results indicate that: (1) The WRF-UCM model, when coupled with LCZ classification, can significantly improve the accuracy of mesoscale urban canopy meteorological field simulations. (2) The water corridors located in the central urban area can effectively regulate the temperature and wind environment during summer. In the high-temperature period of the day, the average temperature in the central city decreases by 0.3–0.4 °C, the heat island proportion index decreases by 1.61 %, and the strong heat island proportion index decreases by 1.89 % in the afternoon. During the period of low temperature, the average wind speed in the central urban area increased by 0.05 m/s increase, and even increased by 0.1 m/s. (3) The specific humidity value of the green corridor is reduced by 0.0000136 kg/kg in comparison to the construction land in the corridor, while the water corridor can increase by 0.000133 kg/kg. If the two kinds of surface, water and green land, are organically combined in the corridor, it will be able to improve the hot and humid conditions in Wuhan in summer. (4)Low-rise and low-density construction land as the corridors in the central urban area can not improve the urban thermal and wind environment. Through an attempt to conduct a complete workflow of urban heat island analysis, ventilation corridor identification and setting, urban climate simulation, analysis and summary, the authors believe that it is an effective set of working methods in sustainable urban planning, design, and policy-making. The implementation of pertinent research findings in the domain of urban planning and design demonstrates its universal applicability and has the potential to extend to analogous research and practice.