This systematic review critically examines the diverse applications of Blockchain technology in the food supply chain and identifies areas where its potential remains underutilized. By analysing 60 Blockchain-based frameworks, the study highlights the most frequently employed drivers such as transparency, traceability, and security within food supply chains. Additionally, underexplored applications such as food donation and redistribution, supply chain financing, animal welfare, food waste management, and data analysis are identified, revealing opportunities for further innovation. The research employed NVivo 14 to analyze the extent of Blockchain’s implementation in various food supply chain drivers, and the findings informed the development of a more diverse framework for Blockchain integration. Key insights demonstrate Blockchain’s transformative potential, particularly in enhancing data integrity, trust, and operational efficiency through its immutable ledger and smart contracts, which streamline transactions, cut administrative costs, and reduce fraud. In terms of sustainability and safety, Blockchain improves traceability, accelerates safety responses, promotes environmental sustainability by tracking resource usage, and enhances humanitarian efforts with transparent, efficient resource distribution. Additionally, Blockchain facilitates food waste reduction by optimizing inventory and distribution, while ensuring surplus food reaches those in need. The study concludes by offering a roadmap for future research, pointing toward untapped dimensions of Blockchain’s application in food traceability, sustainable supply chain management, and environmental & social impact. While the review provides a comprehensive understanding of Blockchain’s current usage in food supply chains, the scope is limited by the systematic review process and specific inclusion criteria. This study serves as a foundation for exploring Blockchain’s broader potential in shaping the future of food supply chains.