In Morocco's oases, which rely heavily on surface water from mountain sources, the threat of decreasing rainfall presents a significant challenge, leading to a decline in surface water availability. This study focuses on the Rheris Watershed in Southeast Morocco, where brackish water desalination emerges as a viable alternative to ensure sustainable water supply for agriculture. Prior to the deployment of a pilot plant integrating a desalination unit, selecting an optimal site for PV-powered MCDI desalination plants was critical. This selection was based on a range of criteria, including Groundwater Quantity, Global Horizontal Irradiation, Temperature, Evaporation, Water Salinity, Water Quantity, Well Density and Slope. These criteria were evaluated using a combination of the Analytical Hierarchy Process (AHP), and geospatial data obtained from Remote Sensing (RS) and Geographic Information System (GIS) techniques.This case study in the Rheris watershed identified potential sites for future Membrane Capacitive Deionization (MCDI) desalination projects, High suitability areas encompass 280.45 km² (30.91 %), located west of Tinejdad, Khettarat Moulay Hachem, north of Goulmima, and south of Tinghir. Low suitability areas cover 63.75 km² (7.02 % of the study area), including regions south of Tadighoust and Tinejdad. Moderate suitability areas span 562.86 km² (62.05 %), involving central regions of Goulmima, Tadighoust, Tinejdad, and Tinghir. Based on the results of the study, the recommendations include focusing on areas identified as highly suitable for MCDI technology for sustainable agriculture, refining selection criteria based on local data, exploring brine management strategies, and adopting integrated water management approaches to ensure sustainable resource use.