Surface-enhanced Raman Scattering Devices Research Articles

Gas Sensor Based on Surface Enhanced Raman Scattering.

In order to address problems of safety and identification in gas detection, an optical detection method based on surface enhanced Raman scattering (SERS) was studied to detect ethanol vapor. A SERS device of silver nanoparticles modified polyvinylpyrrolidone (PVP) was realized by freeze-drying method. This SERS device was placed in a micro transparent cavity in order to inject ethanol vapor of 4% and obtain Raman signals by confocal Raman spectrometer. We compared different types of SERS devices and found that the modification of polyvinylpyrrolidone improves adsorption of ethanol molecules on surfaces of silver nanoparticle, and finally we provide the mechanism by theory and experiment. Finite Difference Time Domain(FDTD) simulation shows that single layer close-packed Ag nanoparticles have strong local electric field in a wide spectral range. In this study, we provide a case for safety and fingerprint recognition of ethanol vapor at room temperature and atmospheric pressure.

3D aluminum/silver hierarchical nanostructure with large areas of dense hot spots for surface-enhanced raman scattering.

Plasmonic nanomaterials possessing large-volume, high-density hot spots with high field enhancement are highly desirable for ultrasensitive surface-enhanced Raman scattering (SERS) sensing. However, many as-prepared plasmonic nanomaterials are limited in available dense hot spots and in sample size, which greatly hinder their wide applications in SERS devices. Here, we develop a two-step physical deposition protocol and successfully fabricate 3D hierarchical nanostructures with highly dense hot spots across a large scale (6×6 cm2 ). The nanopatterned aluminum film was first prepared by thermal evaporation process, which can provide 3Dquasi-periodic cloud-like nanostructure arrays suitable for noble metal deposition; then a large number of silver nanoparticles withcontrollable shape and size were decorated onto the alumina layer surfaces by laser molecular beam epitaxy, which can realize large-area accessible dense hot spots. The optimized 3D-structured SERS substrate exhibits high-quality detection performance with excellent reproducibility (13.1 and 17.1%), whose LOD of rhodamine 6G molecules was 10-9 M. Furthermore, the as-prepared 3D aluminum/silver SERS substrate was applied in detection of melamine with the concentration down to 10-7 M and direct detection of melamine in infant formula solution with the concentration as low 10mg/L. Such method to realize large-area hierarchical nanostructures can greatly simplify the fabrication procedure for 3D SERS platforms, and should be of technological significance in mass production of SERS-based sensors.

Surface-enhanced Raman scattering of dipolar molecules by the graphene Fermi surface modulation with different dipole moments

We report the modulation of Raman scattering spectrum of chromophore/graphene hybrids by tunning the molecular polarization with different terminal groups (methyl, methoxy, nitrile, and two nitros). Based on the density functional theory, the specific dipole moment values of the chromophore molecules are calculated. An obvious surface-enhanced Raman scattering (SERS) was observed and the scattering intensity of molecule increases with enlarged dipole moment. According to the analysis of G band Raman shifts of graphene, the enhancement of the Raman signal can be attributed to strong electronic coupling between graphene and chromophore, which is closely related with the modulation of graphene Fermi surface by changing the dipole moment of the molecule. Besides, the optimization of the ground state geometry and the binding energy of the hybrids were also calculated with the Density Functional Based Tight Bonding (DFTB) method, which confirms that the enhanced Raman scattering of molecules on graphene arises from the improved energy level matching between graphene Fermi surface and molecular band, further providing a new way to design novel SERS devices.

Femtosecond laser fabrication of monolithically integrated microfluidic sensors in glass.

Femtosecond lasers have revolutionized the processing of materials, since their ultrashort pulse width and extremely high peak intensity allows high-quality micro- and nanofabrication of three-dimensional (3D) structures. This unique capability opens up a new route for fabrication of microfluidic sensors for biochemical applications. The present paper presents a comprehensive review of recent advancements in femtosecond laser processing of glass for a variety of microfluidic sensor applications. These include 3D integration of micro-/nanofluidic, optofluidic, electrofluidic, surface-enhanced Raman-scattering devices, in addition to fabrication of devices for microfluidic bioassays and lab-on-fiber sensors. This paper describes the unique characteristics of femtosecond laser processing and the basic concepts involved in femtosecond laser direct writing. Advanced spatiotemporal beam shaping methods are also discussed. Typical examples of microfluidic sensors fabricated using femtosecond lasers are then highlighted, and their applications in chemical and biological sensing are described. Finally, a summary of the technology is given and the outlook for further developments in this field is considered.

Sensitive surface-enhanced Raman scattering active substrate based on gap surface plasmon polaritons

The authors fabricate three types of surface-enhanced Raman scattering (SERS) active substrates by nanoimprint lithography and experimentally investigated the intensity enhancement of Raman scattering induced by gap surface plasmon polaritons (GSPPs). An area-averaged Raman signal enhancement factor of 1.1 × 107 can be achieved by the GSPPs structures for monolayer thiophenol molecules absorbed on silver surfaces, compared with 6.2 × 105 of conventional SERS-active substrates. The exceptional field enhancement originates not only from the localized surface plasmon polaritons but also from the coupling between the GSPPs at two metal/dielectric interfaces. These structures are expected to find promising applications as SERS devices in trace-level molecular detection and identification.

SERS chemical sensors and biosensors: new tools for environmental and biological analysis

This paper describes recent advances in chemical sensors and biosensors based on surface-enhanced Raman scattering (SERS) detection. The SERS-active probes involve silver-coated microstructured substrates designed to amplify the Raman signals of adsorbed molecules and to detect trace chemicals in liquid as well as vapor samples. The development and application of several SERS devices such as a fiber-optic remote sensor and a vapor dosimeter are described. The results illustrate the different uses of the SERS method for the identification and quantification of important environmental and biological compounds.