Binary Support Vector Machine Classifier Research Articles

A support vector machine-based approach to guide the selection of a pseudo-reference region for brain PET quantification.

A Support Vector Machine (SVM) based approach was developed to identify a pseudo-reference region for brain PET scans with the aim of reducing interscan and intersubject variability. By training a binary linear SVM classifier with PET datasets from two different groups, potential pseudo-reference regions were identified by considering their regional average or total contribution to the classification score. This approach was evaluated in three cohorts with different brain PET tracers: (1) 11C-PiB PET scans of Alzheimer's disease (AD) patients and age-matched controls (OC); (2) baseline and blocking scans of an 11C-UCB-J PET occupancy study; and (3) 18F-DPA-714 PET scans for healthy controls (HC) and chemo-treated women with breast cancer (BC). In the first cohort, cerebellum, brainstem, and subcortical white matter were confirmed as pseudo-reference regions. The same regions were identified for the second cohort using either the VT maps or the SUV images. In the third cohort, cerebellum and brainstem were identified as pseudo-reference regions, alongside subcortical white matter and temporal cortex. In addition, the SVM-based approach demonstrated robust performance even with a reduced number of subjects, therefore confirming its applicability in identifying pseudo-reference regions without a priori assumptions and with only limited data across different PET tracers.

In-vivo high-frequency quantitative ultrasound-derived parameters of the anterior sclera correlated with level of myopia and presence of staphyloma.

A high-frequency point-of-care (POC) ultrasound instrument was used to evaluate the microstructural and biomechanical properties of the anterior sclera in vivo using parameters computed from quantitative ultrasound (QUS) methods. In this cross-sectional study, both eyes of 85 enrolled patients were scanned with the POC instrument and ultrasound data were processed to obtain QUS parameters. Pearson correlation and multi-linear regression were used to identify relationships between QUS parameters and refractive error (RE) or axial length. After categorising eyes based on RE, binary support vector machine (SVM) classifiers were trained using the QUS or ophthalmic parameters (anterior chamber depth, central corneal thickness, corneal power, and intraocular pressure) to classify each eye. Classifier performance was evaluated by computing the area under the receiver-operating characteristic curve (AUC). Individual QUS parameters correlated with RE and axial length (p < 0.05). Multi-linear regression revealed significant correlation between the set of QUS parameters and both RE (R = 0.49, p < 0.001) and axial length (R = 0.46, p = 0.001). Classifiers trained with QUS parameters achieved higher AUC (𝑝 = 0.06) for identifying myopic eyes (AUC = 0.71) compared to classifiers trained with ophthalmic parameters (AUC = 0.63). QUS-based classifiers attained the highest AUC when identifying highly myopic eyes (AUC = 0.77). QUS parameters correlate with progressing myopia and may be indicative of myopia-induced microstructural and biomechanical changes in the anterior sclera. These methods may provide critical clinical information complementary to standard ophthalmic measurements for predicting myopia progression and risk assessment for posterior staphyloma formation.

Early warning model based on support vector machine ensemble algorithm

Support Vector Machine (SVM) is a powerful machine learning technique often applied in various early warning scenarios. When using SVM for binary classification, its output results can be converted into a probability distribution based on sample categories. Through the analysis of the results, it is found that when the probability of a sample belonging to a positive class is equivalent to the probability of a sample belonging to a negative class, there is a high possibility of misclassification of the sample. To address this issue, this study proposes a new SVM ensemble model construction method. We generate SVM sub-classifiers to extract error prone set, and utilise three different combination rules to construct ensemble model based on the output probability of the samples. The accuracy of the whole data set is improved for the classification accuracy of the easily misclassified data are improved. This research evaluated the model based on Wind turbine SCADA data and UCI benchmark datasets. According to the research results, the accuracy rate of SCADA data is as high as 97.52%, and the accuracy rate of German credit data is 77.50%. Meanwhile, the comparison with other methods also validates the effectiveness of the proposed method.

Proteome-scale prediction of molecular mechanisms underlying dominant genetic diseases.

Many dominant genetic disorders result from protein-altering mutations, acting primarily through dominant-negative (DN), gain-of-function (GOF), and loss-of-function (LOF) mechanisms. Deciphering the mechanisms by which dominant diseases exert their effects is often experimentally challenging and resource intensive, but is essential for developing appropriate therapeutic approaches. Diseases that arise via a LOF mechanism are more amenable to be treated by conventional gene therapy, whereas DN and GOF mechanisms may require gene editing or targeting by small molecules. Moreover, pathogenic missense mutations that act via DN and GOF mechanisms are more difficult to identify than those that act via LOF using nearly all currently available variant effect predictors. Here, we introduce a tripartite statistical model made up of support vector machine binary classifiers trained to predict whether human protein coding genes are likely to be associated with DN, GOF, or LOF molecular disease mechanisms. We test the utility of the predictions by examining biologically and clinically meaningful properties known to be associated with the mechanisms. Our results strongly support that the models are able to generalise on unseen data and offer insight into the functional attributes of proteins associated with different mechanisms. We hope that our predictions will serve as a springboard for researchers studying novel variants and those of uncertain clinical significance, guiding variant interpretation strategies and experimental characterisation. Predictions for the human UniProt reference proteome are available at https://osf.io/z4dcp/.

SVM-RLF-DNN: A DNN with reliefF and SVM for automatic identification of COVID from chest X-ray and CT images.

To develop an advanced determination technology for detecting COVID-19 patterns from chest X-ray and CT-scan films with distinct applications of deep learning and machine learning methods. The newly enhanced proposed hybrid classification network (SVM-RLF-DNN) comprises of three phases: feature extraction, selection and classification. The in-depth features are extracted from a series of 3×3 convolution, 2×2 max polling operations followed by a flattened and fully connected layer of the deep neural network (DNN). ReLU activation function and Adam optimizer are used in the model. The ReliefF is an improved feature selection algorithm of Relief that uses Manhattan distance instead of Euclidean distance. Based on the significance of the feature, the ReliefF assigns weight to each extracted feature received from a fully connected layer. The weight to each feature is the average of k closest hits and misses in each class for a neighbouring instance pair in multiclass problems. The ReliefF eliminates lower-weight features by setting the node value to zero. The higher weights of the features are kept to obtain the feature selection. At the last layer of the neural network, the multiclass Support Vector Machine (SVM) is used to classify the patterns of COVID-19, viral pneumonia and healthy cases. The three classes with three binary SVM classifiers use linear kernel function for each binary SVM following a one-versus-all approach. The hinge loss function and L2-norm regularization are selected for more stable results. The proposed method is assessed on publicly available chest X-ray and CT-scan image databases from Kaggle and GitHub. The performance of the proposed classification model has comparable training, validation, and test accuracy, as well as sensitivity, specificity, and confusion matrix for quantitative evaluation on five-fold cross-validation. Our proposed network has achieved test accuracy of 98.48% and 95.34% on 2-class X-rays and CT. More importantly, the proposed model's test accuracy, sensitivity, and specificity are 87.9%, 86.32%, and 90.25% for 3-class classification (COVID-19, Pneumonia, Normal) on chest X-rays. The proposed model provides the test accuracy, sensitivity, and specificity of 95.34%, 94.12%, and 96.15% for 2-class classification (COVID-19, Non-COVID) on chest CT. Our proposed classification network experimental results indicate competitiveness with existing neural networks. The proposed neural network assists clinicians in determining and surveilling the disease.

Face spoofing detection using Heterogeneous Auto-Similarities of Characteristics

Facial recognition systems are widely used in various daily applications due to their high accuracy rate and ease of use. Unfortunately, their performance drops drastically when encountering spoofing attacks. In this paper, a novel pipeline for face spoofing detection based on the extraction of Heterogeneous Auto-Similarities of Characteristics (HASC) descriptor from the HSV and YCbCr color spaces is proposed. To detect print and replay spoofing attacks, the HASC descriptor encodes linear and non-linear dependencies between low-level dense features of the color face image using covariance and information-theoretic measures. The combination of covariance and information-theoretic measures makes HASC an efficient descriptor to explore how the features are interrelated in real and fake faces. The HASC texture descriptions are extracted separately from each color channel of the HSV and YCbCr color spaces, and the resulting feature vectors are concatenated into an extended feature vector to better discriminate between real and fake faces. Extensive experiments are conducted on publicly available databases namely, Replay-Attack, CASIA FASD, and MSU MFSD. The obtained results demonstrate that while being of low dimension, the HASC descriptor when fed into a binary Support Vector Machine (SVM) classifier, achieves competitive results compared to the state-of-the-art.

Sports video summarization using acoustic symmetric ternary codes and SVM

Broadcasters produce and transmit a vast number of sports videos in cyberspace due to immense viewership and potential commercial benefits. The analysis and processing of such a huge amount of video content are very challenging. This situation demands the development of effective and efficient summarization methods to manage the massive sports video repository while keeping the viewer’s interest along with potential storage and transmission benefits. This paper presents an automated summarization framework based on excitement detection for sports videos i.e., cricket, soccer, etc. The audio stream of the sports video is analyzed to capture the significant events that are then used to produce the concise video. For effective representation of audio signals, we proposed an acoustic feature descriptor symmetric ternary codes and used them to train a binary Support Vector Machine classifier for excitement detection. Each audio frame is labeled as either an excited audio frame or a non-excited audio frame. The video frames corresponding to the excited audio frames represent the key-events in the sports videos and are marked as the key-frames. Each key-frame is appended with the neighboring frames to produce video skims for each key-event based on the user’s required summary length. Finally, these video skims are sequentially arranged to produce the user-driven video summary. We evaluated our highlights generation method on our own diverse YouTube dataset of cricket and soccer videos, and a largescale SoccerNet corpus of soccer videos. The average accuracy of 97.7% and 91.23% on both datasets confirms the reliability of our method in terms of key-event detection for sports highlight generation.

Determining optimal bead central angle by applying machine learning to wire arc additive manufacturing (WAAM)

Wire arc additive manufacturing (WAAM) is being extensively used in various industrial fields. In WAAM, if a bead is deposited without considering the central angle, its shape may collapse with increasing number of layers. To address this problem, a new method for optimizing the bead geometry using a support vector machine (SVM) classifier was established in this study. The ranges of the optimal deposition conditions were determined using the SVM classifier and verified by experiments. Geometric data of deposited beads were extracted using a laser profiler, and an SVM binary classifier was used to predict suitable ranges of the deposition conditions. Data were extracted through 20 single-layer basic experiments, classification was performed based on 4°, and the appropriateness of SVM classification was found through 8 single-layer and 3 multi-layer verification experiments.The results showed that the SVM classifier successfully selected the ranges of the optimal deposition conditions. Verification experiments revealed that the results in all cases were appropriately classified based on the boundary of the classification line. Moreover, the SVM classifier was efficient even when a small amount of input data was available. The contribution of this study is that the developed method can help build desired bead geometries in scenarios where deposition is required in the WAAM process, such as re-manufacturing. Thus, this method can be used in real-world industrial applications through further research on the bead shape with multi-layer deposition.

Identification of DNA methylation episignature for the intellectual developmental disorder, autosomal dominant 21 syndrome, caused by variants in the CTCF gene

PurposeThe main objective of this study was to assess clinical features and genome-wide DNA methylation profiles in individuals affected by intellectual developmental disorder, autosomal dominant 21 (IDD21) syndrome, caused by variants in the CCCTC-binding factor (CTCF) gene. MethodsDNA samples were extracted from peripheral blood of 16 individuals with clinical features and genetic findings consistent with IDD21. DNA methylation analysis was performed using the Illumina Infinium Methylation EPIC Bead Chip microarrays. The methylation levels were fitted in a multivariate linear regression model to identify the differentially methylated probes. A binary support vector machine classification model was constructed to differentiate IDD21 samples from controls. ResultsWe identified a highly specific, reproducible, and sensitive episignature associated with CTCF variants. Six variants of uncertain significance were tested, of which 2 mapped to the IDD21 episignature and clustered alongside IDD21 cases in both heatmap and multidimensional scaling plots. Comparison of the genomic DNA methylation profile of IDD21 with that of 56 other neurodevelopmental disorders provided insights into the underlying molecular pathophysiology of this disorder. ConclusionThe robust and specific CTCF/IDD21 episignature expands the growing list of neurodevelopmental disorders with distinct DNA methylation profiles, which can be applied as supporting evidence in variant classification.

Fusion extracted features from deep learning for identification of multiple positioning errors in dental panoramic imaging.

Dental panoramic imaging plays a pivotal role in dentistry for diagnosis and treatment planning. However, correctly positioning patients can be challenging for technicians due to the complexity of the imaging equipment and variations in patient anatomy, leading to positioning errors. These errors can compromise image quality and potentially result in misdiagnoses. This research aims to develop and validate a deep learning model capable of accurately and efficiently identifying multiple positioning errors in dental panoramic imaging. This retrospective study used 552 panoramic images selected from a hospital Picture Archiving and Communication System (PACS). We defined six types of errors (E1-E6) namely, (1) slumped position, (2) chin tipped low, (3) open lip, (4) head turned to one side, (5) head tilted to one side, and (6) tongue against the palate. First, six Convolutional Neural Network (CNN) models were employed to extract image features, which were then fused using transfer learning. Next, a Support Vector Machine (SVM) was applied to create a classifier for multiple positioning errors, using the fused image features. Finally, the classifier performance was evaluated using 3 indices of precision, recall rate, and accuracy. Experimental results show that the fusion of image features with six binary SVM classifiers yielded high accuracy, recall rates, and precision. Specifically, the classifier achieved an accuracy of 0.832 for identifying multiple positioning errors. This study demonstrates that six SVM classifiers effectively identify multiple positioning errors in dental panoramic imaging. The fusion of extracted image features and the employment of SVM classifiers improve diagnostic precision, suggesting potential enhancements in dental imaging efficiency and diagnostic accuracy. Future research should consider larger datasets and explore real-time clinical application.

Multi-Frequency 3D Shear Wave Absolute Vibro-Elastography (S-WAVE) System for the Prostate.

This article describes a novel system for quantitative and volumetric measurement of tissue elasticity in the prostate using simultaneous multi-frequency tissue excitation. Elasticity is computed by using a local frequency estimator to measure the three-dimensional local wavelengths of steady-state shear waves within the prostate gland. The shear wave is created using a mechanical voice coil shaker which transmits simultaneous multi-frequency vibrations transperineally. Radio frequency data is streamed directly from a BK Medical 8848 transrectal ultrasound transducer to an external computer where tissue displacement due to the excitation is measured using a speckle tracking algorithm. Bandpass sampling is used that eliminates the need for an ultra-fast frame rate to track the tissue motion and allows for accurate reconstruction at a sampling frequency that is below the Nyquist rate. A roll motor with computer control is used to rotate the transducer and obtain 3D data. Two commercially available phantoms were used to validate both the accuracy of the elasticity measurements as well as the functional feasibility of using the system for in vivo prostate imaging. The phantom measurements were compared with 3D Magnetic Resonance Elastography (MRE), where a high correlation of 96% was achieved. In addition, the system has been used in two separate clinical studies as a method for cancer identification. Qualitative and quantitative results of 11 patients from these clinical studies are presented here. Furthermore, an AUC of 0.87±0.12 was achieved for malignant vs. benign classification using a binary support vector machine classifier trained with data from the latest clinical study with leave one patient out cross-validation.

A novel framework for the diagnosis of Parkinson’s disease using transfer learning with RESNET50 and SVM classifier

&lt;span&gt;Most Parkinson’s patients exhibit voice disorders in the early phases of the condition. Recent study on Parkinson’s disease (PD) has concentrated on identifying speech problems from pronunciation of vowels with people affected by this disease. Proposed algorithm offers analysis of time-frequency images using transfer learning methods with support vector machine (SVM) for classification of PD affected with healthy controls using residual network 50. PD morphology is preserved in 2-dimensional time-frequency graphs &lt;br /&gt; that were helpful in implementing the proposed approach. The technique employs a hybrid HT/Wigner-Ville distribution to convert one-dimensional PD soundtracks to two-dimensional time-frequency (TF) graphs. After implementation of the proposed approach, classification of healthy and unhealthy controls is done using a pre-trained ResNet50 and the result is further improved through transfer learning. The features are extracted by passing preprocessed 2-D time-frequency diagrams through ResNet50’s FC1000 layer and trained using a binary nonlinear SVM classifier. The training process with 5-fold cross-validation (CV) got accuracy of 95.07% and in testing; it reached 92.13%, attaining better results.&lt;/span&gt;

A Filter-SQP strategy for training Support Vector Machine models

This paper introduces a filtering strategy for addressing optimization problems arising in binary Support Vector Machine classification. The training optimization problem aims to solve the dual formulation which involves a quadratic objective function subjected to a linear and box constraints. Our approach employs a Filter algorithm with Sequential Quadratic Programming iterations that minimize the quadratic Lagrangian approximations. Notably, we utilize the exact Hessian matrix in our numerical experiments to seek the desired classification function. Moreover, we present a Filter algorithm combined with the Augmented Lagrangian method aiming to accelerate the algorithm convergence. To substantiate our method's effectiveness, we conduct numerical experiments through MATLAB, comparing outcomes with alternative methodologies detailed in existing literature. Numerical experiments shows that the Filter--SQP combined with Augmented Lagrangian method is competitive and efficient method compared with an interior-point based solver and LIBSVM software in relation of classification metrics and CPU-time.

Relative importance of speech and voice features in the classification of schizophrenia and depression

Speech is a promising biomarker for schizophrenia spectrum disorder (SSD) and major depressive disorder (MDD). This proof of principle study investigates previously studied speech acoustics in combination with a novel application of voice pathology features as objective and reproducible classifiers for depression, schizophrenia, and healthy controls (HC). Speech and voice features for classification were calculated from recordings of picture descriptions from 240 speech samples (20 participants with SSD, 20 with MDD, and 20 HC each with 4 samples). Binary classification support vector machine (SVM) models classified the disorder groups and HC. For each feature, the permutation feature importance was calculated, and the top 25% most important features were used to compare differences between the disorder groups and HC including correlations between the important features and symptom severity scores. Multiple kernels for SVM were tested and the pairwise models with the best performing kernel (3-degree polynomial) were highly accurate for each classification: 0.947 for HC vs. SSD, 0.920 for HC vs. MDD, and 0.932 for SSD vs. MDD. The relatively most important features were measures of articulation coordination, number of pauses per minute, and speech variability. There were moderate correlations between important features and positive symptoms for SSD. The important features suggest that speech characteristics relating to psychomotor slowing, alogia, and flat affect differ between HC, SSD, and MDD.

Modifying linearly non-separable support vector machine binary classifier to account for the centroid mean vector

Modifying linearly non-separable support vector machine binary classifier to account for the centroid mean vector

Real-Time Parking Using AI &amp; ML

Real time parking systems have a potential to reduce the congestion in crowded areas by providing real time indications of occupancy of parking spaces. To date, search systems are mostly implemented for indoor environments using costly sensor based techniques. Consequently, with the increasing demand for parking systems in outdoor environments, inexpensive image based detection methods have become a focus of research and development recently. Motivated by the remarkable performance of Convolutional Neural Networks (CNNs) in various image category recognition tasks, this study presents a robust parking occupancy detection framework by using a deep CNN and a binary Support Vector Machine (SVM) classifier to detect the occupancy of outdoor parking spaces images. The classifier was trained and tested why the features learned by the deep CNN (convolutional neural network) from public datasets (PKlot) having different illuminance and weather conditions. The indicates the great potential of this method to provide a low- cost and reliable solution to the parking systems in outdoor environments.

Dissolved Gas Analysis and Application of Artificial Intelligence Technique for Fault Diagnosis in Power Transformers: A South African Case Study

In South Africa, the growing power demand, challenges of having idle infrastructure, and power delivery issues have become crucial problems. Reliability enhancement necessitates a life-cycle performance analysis of the electrical power transformers. To attain reliable operation and continuous electric power supply, methodical condition monitoring of the electrical power transformer is compulsory. Abrupt breakdown of the power transformer instigates grievous economic detriment in the context of the cost of the transformer and disturbance in the electrical energy supply. On the condition that the state of the transformer is appraised in advance, it can be superseded to reduced loading conditions as an alternative to unexpected failure. Dissolved gas analysis (DGA) nowadays has become a customary method for diagnosing transformer faults. DGA provides the concentration level of various gases dissolved, and consequently, the nature of faults can be predicted subject to the concentration level of the gases. The prediction of fault class from DGA output has so far proven to be not holistically reliable when using conventional methods on account of the volatility of the DGA data in line with the rating and working conditions of the transformer. Several faults are unpredictable using the IEC gas ratio (IECGR) method, and an artificial neural network (ANN) has the hindrance of overfitting. Nonetheless, considering that transformer fault prediction is a classification problem, in this work, a unique classification algorithm is proposed. This applies a binary classification support vector machine (BCSVM). The classification precision is not reliant on the number of features of the input gases dataset. The results indicate that the proposed BCSVM furnishes improved results concerning IECGR and ANN methods traceable to its enhanced generalization capability and constructional risk-abatement principle.

Improving pre-movement pattern detection with filter bank selection

Objective. Pre-movement decoding plays an important role in detecting the onsets of actions using low-frequency electroencephalography (EEG) signals before the movement of an upper limb. In this work, a binary classification method is proposed between two different states. Approach. The proposed method, referred to as filter bank standard task-related component analysis (FBTRCA), is to incorporate filter bank selection into the standard task-related component analysis (STRCA) method. In FBTRCA, the EEG signals are first divided into multiple sub-bands which start at specific fixed frequencies and end frequencies that follow in an arithmetic sequence. The STRCA method is then applied to the EEG signals in these bands to extract CCPs. The minimum redundancy maximum relevance feature selection method is used to select essential features from these correlation patterns in all sub-bands. Finally, the selected features are classified using the binary support vector machine classifier. A convolutional neural network (CNN) is an alternative approach to select canonical correlation patterns. Main Results. Three methods were evaluated using EEG signals in the time window from 2 s before the movement onset to 1 s after the movement onset. In the binary classification between a movement state and the resting state, the FBTRCA achieved an average accuracy of 0.8968 ± 0.0847 while the accuracies of STRCA and CNN were 0.8228 ± 0.1149 and 0.8828 ± 0.0917, respectively. In the binary classification between two actions, the accuracies of STRCA, CNN, and FBTRCA were 0.6611 ± 0.1432, 0.6993 ± 0.1271, 0.7178 ± 0.1274, respectively. Feature selection using filter banks, as in FBTRCA, produces comparable results to STRCA. Significance. The proposed method provides a way to select filter banks in pre-movement decoding, and thus it improves the classification performance. The improved pre-movement decoding of single upper limb movements is expected to provide people with severe motor disabilities with a more natural, non-invasive control of their external devices.

Acoustic rainfall estimation with support vector machines and error correcting output codes

Ma and Nystuen (2005) successfully detected and estimated rainfall at sea from passive acoustics. They detected rain from three narrowband frequencies and then estimated log rainfall rate via a regression with energy in the 5 kHz band. Mallary et al. (2022) improved rainfall detection by exploiting broadband spectra while reducing the dimensionality through principal component analysis (PCA). This project builds upon Mallary’s work moving beyond detection to estimate the rainfall by quantization into discrete ranges based on PCA-reduced acoustic power spectra. The classification scheme combines multiple binary support-vector machine (SVM) classifiers (Boser et al. 1992) with Dietterich and Bakiri’s error-correcting output codes (1995) to classify acoustic PSDs into one of 6 rainfall rate classes. Evaluating the PCA/SVM classifier on 4 months of acoustic recordings and meteorological data collected from a shallow water pier in New Bedford, MA found the hourly accumulations from the rain gauge and acoustic estimates had a correlation of 0.97 ± 0.01. Emulating Ma &amp; Nystuen’s estimator on the same data set yields a correlation of 0.76 ± 0.02. [Work supported by ONR.]

Automated Machine Learning Pipeline Framework for Classification of Pediatric Functional Nausea Using High-Resolution Electrogastrogram.

Pediatric functional nausea is challenging for patients to manage and for clinicians to treat since it lacks objective diagnosis and assessment. A data-driven non-invasive diagnostic screening tool that distinguishes the electro-pathophysiology of pediatric functional nausea from healthy controls would be an invaluable aid to support clinical decision-making in diagnosis and management of patient treatment methodology. The purpose of this paper is to present an innovative approach for objectively classifying pediatric functional nausea using cutaneous high-resolution electrogastrogram data. We present an Automated Electrogastrogram Data Analytics Pipeline framework and demonstrate its use in a 3x8 factorial design to identify an optimal classification model according to a defined objective function. Low-fidelity synthetic high-resolution electrogastrogram data were generated to validate outputs and determine SOBI-ICA noise reduction effectiveness. A 10 parameter support vector machine binary classifier with a radial basis function kernel was selected as the overall top-performing model from a pool of over 1000 alternatives via maximization of an objective function. This resulted in a 91.6% test ROC AUC score. Using an automated machine learning pipeline approach to process high-resolution electrogastrogram data allows for clinically significant objective classification of pediatric functional nausea. To our knowledge, this is the first study to demonstrate clinically significant performance in the objective classification of pediatric nausea patients from healthy control subjects using experimental high-resolution electrogastrogram data. These results indicate a promising potential for high-resolution electrogastrography to serve as a data-driven screening tool for the objective diagnosis of pediatric functional nausea.