Patients are increasingly turning to social media as a source of emotional support and medical information. The objective of this study is to analyze the nature and accuracy of social media (Facebook) content related to endometriosis. A search of public Facebook pages during Endometriosis Awareness Month (March 2020) was performed using the key word “endometriosis.” Posts from the study period were categorized and analyzed for accuracy. Posts were placed into 11 categories through thematic evaluation by two independent researchers. Categories included the following: educational, emotional support, advocacy, discussion, events, humor, promotional, recipes, resources, surveys, and other. Posts categorized as “educational” were further subcategorized and reviewed. Each posted fact was cross-referenced in peer-reviewed scientific journals to determine whether the claim made was evidence-based. To analyze the effect of post category on engagement in the post, we used Kruskal-Wallis chi-squared tests, and Pearson's correlation test to analyze correlation between engagement in evidenced based posts. Ninety-three Facebook pages were identified using the search term “endometriosis,” and 1,464 posts from the study period were evaluated. Emotional support posts comprised the largest category of posts (48%), followed by educational (21%), events (10.3%), promotional (6.1%), humor (4.7%), discussion (3.6%), advocacy (2.6%), other (1.1%), recipes (0.83%), resources (0.76%), and surveys (0.34%). Within the educational category, the epidemiology and pathophysiology subcategory comprised the largest subcategory (42.0%), followed by symptoms (19.6%), pharmaceutical treatment (7.8%), peer-reviewed papers (7.5%), surgery (5.6%), fertility (5.3%), other (4.7%), diagnosis (3.8%), alternative treatments (2.8%), and advocacy (1.3%). Results show that post category had an effect on the amount of engagement in a post (P value < 0.001). Emotional posts had 70% of the overall engagement while educational posts had 20%. A similar effect of the sub-categories of the educational posts on engagement was also seen (P value = 0.0007). Posts were more engaging if they contained epidemiology and pathophysiology information, with 44% of all engagement of educational posts being within this subcategory. There was no correlation between engagement in a post and how accurate the post was (P value = 0.3117). Educational posts were found to be 93.93% accurate. Facebook pages offer emotional support and education to people with endometriosis. A majority of the information found in these Facebook pages is evidence-based. Healthcare providers should consider discussing the use of Facebook pages as a resource for their patients diagnosed with endometriosis.