Decarbonizing the EU's district heating is crucial for meeting climate goals and securing a sustainable energy future. Currently, district heating suffers from inefficiency, high operating temperatures, significant distribution losses, and reliance on fossil fuels. Literature highlights strategies for reducing emissions, including integrating low-carbon heat sources, lowering supply temperatures, and employing efficient technologies like heat pumps and combined heat and power (CHP). However, the individual effectiveness of these strategies in reducing emissions within existing networks remains unassessed. This study addresses the gap by applying a comprehensive model that evaluates energy and emissions across the district heating supply chain, coupled with a derivative-based sensitivity analysis. We apply this methodology to the national-level district heating systems of Sweden, France, Germany, and Poland. Results indicate that the impact of decarbonization strategies on district heating emissions varies significantly by the system's characteristics, i.e., the energy mix in power and district heating supply and the presence of CHP plants. Primarily, incorporating more low-carbon heat sources emerges as the most effective method for emission reduction across nearly all examined countries. A 1 % increase in the share of low-carbon heat sources can potentially cut emissions by 0.8–1.3 kg CO2e per GJ of heat. In countries like Sweden and France, where the power generation already relies heavily on low-carbon resources, technologies which convert electricity to heat—such as heat pumps and electric boilers—rank as the second most effective approach. In contrast, for countries like Germany and Poland, with their moderate to low use of low-carbon power, reducing distribution losses and decreasing heat demand prove more effective, with emission reductions ranging between 0.8-1.3 and 0.7–1.2 kg CO2e per GJ in these countries, respectively. Additionally, cutting down power generation in fossil fuel-based CHP plants significantly reduces emissions in these regions. While green hydrogen and carbon capture and storage (CCS) also contribute to emission reductions, a 1 % increase in green hydrogen's share might decrease emissions by just 0.3–0.5 kg CO2e per GJ of heat, highlighting their lower effectiveness compared to the aforementioned strategies. These insights hold value for both district heating operators and for technology suppliers seeking decarbonization pathways. This is also true for policymakers focused on climate change mitigation, guiding the distribution of subsidies and R&D investments.