We study 4-dimensional mathcal{N} = 2 superconformal quiver gauge theories obtained with an orbifold projection from mathcal{N} = 4 SYM, and compute the 2- and 3-point correlation functions among chiral/anti-chiral single-trace scalar operators and the corresponding structure constants. Exploiting localization, we map the computation to an interacting matrix model and obtain expressions for the correlators and the structure constants that are valid for any value of the ’t Hooft coupling in the planar limit of the theory. At strong coupling, these expressions simplify and allow us to extract the leading behavior in an analytic way. Finally, using the AdS/CFT correspondence, we compute the structure constants from the dual supergravity theory and obtain results that perfectly match the strong-coupling predictions from localization.