Objective - to detect the features of the functional state of the cardiovascular system ofpatients with IInd stage of essential hypertension depending on the types of circadianrhythm of blood pressure.Material and methods. All 62 patients underwent daily blood pressure monitoring usingthe "Solvаig" hardware suite with the corresponding software. According to protocol ofthe research the list of examinations included: average daily, night and daytime bloodpressure, average dynamical blood pressure for the same periods. Besides, an ultrasound examination of the heart was performed to all patients using the "En visor" apparatus(RDC.).Results. All 62 patients with essential hypertension of IInd stage with II-III degree ofblood pressure increase were divided into 3 groups due to the circadian structure ofblood pressure: " Dipper" -26; "Non dipper"-28; and "Night picker" -8. It has beenfound that the basic parameters of the central (cardiac) hemodynamics in the mentioned groups are not unambiguous. Patients with the daily index "Dipper" had theprevalence of normokinetic type of hemodynamics, in contrast to patients with "Nondipper" and "Night picker", who had predominantly hypokinetic type of hemodynamics, confirmed by ratios of these indicators to the body surface and weight. Thesteady high daily average level of blood pressure in "non-dippers" patients, especiallyin "Night pickers", contributes to the formation of a high baseline level of generalperipheral vascular resistance with adaptation in these patients to the hypokinetic typeof central hemodynamics. In addition, the parallels between the body mass index (BMI)and the left ventricular mass index (LVMI) suggest the increase of mismatch betweenBMI and LVMI, which might aggravates from "Dipper" to "Night pickers", which canexacerbate the metabolic imbalance of the myocardium. Analysis of the central venouspressure indices by the circadian rhythm of blood pressure suggests that a largeproportion of patients with low and negative DI arterial hypertension is combined withvenous hypertension, which results in changes in pathogenetic approaches to successfulantihypertensive treatment.Conclusions. 1. Patients with essential hypertension of IInd stage ("Non dipper" and"Night picker") mostly have the hypokinetic type of cerebral hemodynamics with highgeneral peripheral vascular resistance and low kinetic properties of cardiac hemodynamics. 2. Patients with low and negative daily index of circadian blood pressurestructure - "Non dippers" and "Night pickers" have a higher degree of the left ventricular wall hypertrophy and increasing inconformity of the left ventricular myocardialmass index as to the body weight index with deficiency of the myocardial mass to thebody mass, which can increase the metabolic imbalance of the myocardium. 3. According to the type of essential hypertension stage II, patients with circadian rhythmblood pressure - "Non dipper" and, especially, "Night picker"-arterial hypertension arecombined with venous (AVH), respectively, in 46% and 80% of cases, compared with'Dipper' - 40%, which possibly causes an increase in number of treatment-resistants,acceleration of essential hypertension progressions.