Fly ash and bottom ash are ash produced from the process of burning coal as a source of energy in the steam generating unit of a coal-fired power plant (PLTU). Bottom ash is ash that forms at the bottom of a coal-burning furnace and settles there. In this research, fly ash is used as filler substitution and bottom ash is used as fine aggregate substitution (sand). The purpose of the study was to obtain a suitable Job Mix Design (JMD) for Asphalt Concrete - Binder Course (AC-BC) with fly ash and bottom ash substitution materials. To determine the effect of optimum asphalt content on the values of stability, flow, Marshall Quotient, VMA, VIM and VFB obtained from result of the Masrhall test. Based on the results of Marshall testing, the results show that Analysis Stability Of Binder Course Asphalt Concrete (AC-BC) With Fly Ash And Bottom Ash Substitution Material produces the highest VMA value of 14.462% and the highest VIM value of -1.88%, meaning that there are many gaps in the mixture containing asphalt so that it becomes waterproof and hermetic. The highest stability and MQ values are stability of 1955.55.34 kg and MQ of 1241.13 kg/mm. The appropriate Job Mix Design (JMD) for Asphalt Concrete - Binder Course (AC-BC) with fly ash and bottom ash substitution materials is the composition of Fly Ash at 0%, 50%, and 60% of the total cement while for the use of Bottom Ash from the total sand at 0%, 50%, and 60%.