Suicidal Ideation Research Articles

Suicidal risk in youth experiencing homelessness: patterns associated with problem-solving and cognitive distortions

ABSTRACT Introduction Youth experiencing homelessness (YEH) exhibit depressive symptoms and suicidal ideation at much higher rates than the general population (Burke et al., 2022) [Systematic review: Rates of psychopathology, substance misuse, and neuropsychological dysfunction among transitional age youth experiencing homelessness. The American Journal on Addictions, 31(6), 523–534], with suicide the leading cause of mortality among YEH (Auerswald et al., 2016) [Six-year mortality in a street-recruited cohort of homeless youth in San Francisco, California. PeerJ, 4, e1909], likely due to a confluence of stressors (Budescu et al., 2021) [Discrimination, self-harming behaviors and emotional quality of life among youth experiencing homelessness. Journal of Social Distress and Homelessness, 1–10]. To better prevent suicide, understanding factors associated with suicidal risk, such as cognitive distortions and problem-solving, has been a focus of prior research (Wilson et al., 2011) [The role of problem orientation and cognitive distortions in depression and anxiety interventions for young adults. Advances in mental health, 10(1), 52–61]. However, little is known about the relationship between these factors and suicidal risk among YEH. Method Using baseline data from a study with suicidal YEH (N = 150), correlation and mediation analyses were completed to determine the associations between cognitive distortions, problem-solving, depressive symptoms, and suicidal ideation. Results Higher cognitive distortions and poorer problem-solving were significantly associated with depressive symptomology. Additionally, negative problem orientation was a significant mediator of the pathway between cognitive distortions and depressive symptoms. However, we found no relationships among the variables to suicidal ideation. Likewise, sex-at-birth was not significant as a moderator. Conclusion Findings suggest that negative problem orientation could be an important target for preventing depressive symptoms among YEH experiencing cognitive distortions, and future research is recommended to confirm this relationship.

Psychometric Properties of the Beck Scale for Suicidal Ideation in a Diverse Sample.

Suicidal ideation disproportionately impacts minoritized populations; yet, these populations have been historically underrepresented in the development and validation of risk assessments, including the Beck Scale for Suicidal Ideation (BSS). The current study investigated the psychometric properties of the BSS in a combined sample (N = 1,026) of minoritized adults to examine its generalizability across diverse identities. Item response theory (IRT) models were estimated, and parameters including differential item functioning (DIF) were evaluated. Results showed that the original BSS and a 5-item BSS devised in a majority-aligning sample had significant model misspecification in the current study's diverse sample, but a reduced 14-item and 8-item scale has good properties and may be better-performing alternatives. DIF results supported measurement invariance of the BSS across race/ethnicity, sexual orientation, social class, and history of suicide attempts. Inclusion of certain suicidal behaviors (e.g., writing a note) into an assessment of suicidal ideation may not be effective.

Abstract 1851: Development of a smart nanocarrier system for prostate cancer immunotherapy

Abstract Prostate cancer (PCa) is characterized by the overexpression of monoamine oxidase-A (MAO-A), a driver of tumor growth, metastasis, and treatment resistance. Monoamine oxidase inhibitors (MAOIs), such as phenelzine, have shown promise as repurposed agents for PCa therapy. However, systemic administration of phenelzine at effective doses carries significant risks of neuropsychiatric side effects, including aggression, seizures, and suicidal ideation, highlighting the need for a targeted delivery approach. This study aims to develop a smart nanocarrier system for the co-delivery of phenelzine (PHE) and the anti-programmed death ligand 1 (PD-L1) peptide (C7), enhancing therapeutic efficacy while reducing off-target effects. The nanocarrier employs a pH-sensitive hydrazone bond and a matrix metalloproteinase-2 (MMP-2) cleavable linker to achieve site-specific drug release. The system integrates polyethylene glycol-hydrazone-phenelzine (PEG-HZ-PHE) and an MMP-2cleavable linker tethered to the anti-PD-L1 peptide (C7-MMP2), into a lipid nanocarrier platform. Characterization using dynamic light scattering (DLS) revealed a particle size of 190.0 ± 3.9 nm, a polydispersity index (PDI) of 0.17 ± 0.02, and a zeta potential of -33.6 ± 1.3 mV. pH-dependent release studies showed that phenelzine release was highest at pH 5.4 (74.7 ± 0.6%) and lowest at pH 7.4 (11.3 ± 0.1%) after 18 hours, with a 42.3 ± 0.6% release at pH 6.4. Enzyme cleavage studies demonstrated that 73.8 ± 14.5 % of C7 was released within 4 hours of incubation with MMP-2 enzyme, with only 20.3 ± 2.1% of C7-MMP2 remaining after the same period. Cytocompatibility assessment using a red blood cell (RBC) hemolysis assay showed no significant hemolytic activity compared to the negative control (PBS buffer), while the positive control (0.5% Triton X-100) caused significant hemolysis. In conclusion, the developed dual-responsive nanocarrier is stable at physiological pH (7.4) but efficiently releases therapeutic agents in acidic and MMP-2 enzyme-rich environments, offering potential for improved PCa therapy by minimizing off-target effects. Citation Format: Imani Roundtree, Angelo Altenor, Rodney Valdivia, Tovah St. Ignac, Alexandra Esposito, Karelys DiazDavila, Richard Lamptey, John Fetse. Development of a smart nanocarrier system for prostate cancer immunotherapy [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 (Regular Abstracts); 2025 Apr 25-30; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2025;85(8_Suppl_1):Abstract nr 1851.

The cost of implementing and sustaining an evidence-based, behavioral-health electronic screening system in probation departments.

Roughly 50%-75% of youths who have had contact with the juvenile justice system have a mental-health disorder. In 2019, a northeastern state required probation departments to implement an evidence-based behavioral health (BH) screen. e-Connect is a digital clinical decisional support system designed to identify suicide thoughts and behaviors and related BH risk and triage youths based on BH need, then facilitate linkage to care. Toidentify the resources and estimate the costs required to implement and sustaine-Connect from probation-department and policymaker perspectives. Prospective micro-costing analysis conducted concurrently with a rigorous evaluation of e-Connect. Data were collected for 622 youths ages 10-18 via administrative records, study instruments, and semi-structured interviews. Resources/costs were categorized as "fixed", "time-dependent", or "variable". Mean annual costs (per-county and per-screen, by county) were calculated for two intervention phases, "implementation" and "sustainment". All costs are in 2019 USD. The policymaker-relevant, annualized, mean, per-county start-up and sustainment costs were $18,704 (SD = $14,320) and $13,374 (SD = $13,317), respectively. The per-screen sustainment cost was $115 (SD = $113) across counties, with variation attributed to a combination of a county's behavioral-health needs, and differences in the types of resources utilized as part of their post-screening clinical response. The results of this analysis willinform the decisions of probation departments and their stakeholders, who are interested in implementing an evidence-based behavioral-health screen for youths on probation. Site-level figures will provide important details regarding theresources/costs associated withvariousimplementation and management strategies. Cross-site, per-person averages willprovidecrucial inputs intobudget impact modelsandcost-effectiveness analyses.

Moderate-to-Vigorous Physical Activity and Suicidal Ideation in Adolescents with Attention Deficit/Hyperactivity Disorder: the Mediating Effects of Mental Health.

This study aimed to (a) examine whether device-assessed moderate-to-vigorous physical activity (MVPA) was associated with suicidal ideation (SI) in adolescents with attention-deficit/hyperactivity disorders (ADHD), (b) investigate whether the association was mediated by depression, and (c) assess whether anxiety, stress, and resilience would work with depression to constitute chain mediation paths between MVPA and SI. Sixty adolescents with ADHD aged 12-17 (Mage = 14.33 ± 1.43 years) met the inclusion criteria. MVPA data were assessed using accelerometers worn around the waist for seven consecutive days. SI, depression, anxiety, stress, and resilience were examined using self-report questionnaires. Bivariate correlations were estimated for all variables. Lavaan package was used to examine the association between MVPA and SI, and the mediating effects of depression, anxiety, stress, and resilience by adjusting for a minimally sufficient confounder set and applying the bootstrap method. MVPA was negatively associated with SI. Depression fully mediated this association. Anxiety, stress, and resilience combining with depression formed three chain mediation paths between MVPA and SI, respectively. The integrative mediation model, including anxiety, stress, resilience, and depression, revealed that anxiety and depression explained 38.2% of the variance in the association between MVPA and SI, and resilience and depression explained 22.1%, while stress did not. MVPA could serve as an alternative or adjunctive approach, particularly in conjunction with depression-focused interventions, to increase resilience, decrease anxiety and depression, and in turn to prevent or attenuate SI in adolescents with ADHD.

Study-Related Predictors for Depression, Suicidal Ideation and Suicide Risk in German Veterinary Medical Students

Background/Objectives: Compared to the general population in Germany, higher risks for depression, suicidal ideation and suicide risk have been reported for German veterinary students. This study assessed various demographic and study-related risk factors for depression, suicidal ideation and suicide risk for the first time. Methods: An online survey was conducted among German veterinary students to determine demographic and study-related characteristics, study conditions, depression, suicidal ideation, suicide risk, Effort–Reward Imbalance (ERI student version) and motivation and achievement goals (Achievement Goal Inventory) during studies. Data of 913 German veterinary students (90.7% female) aged 18 to 46 years (mean age 23.6 years) were analyzed (response rate 14.3%). Hierarchical logistic regression analyses were conducted, with depression, suicidal ideation and suicide risk as dependent variables and demographic as well as study-related factors as independent variables. Results: With the factors used, the variance explanation was highest for depression, followed by suicidal ideation and suicide risk. Low reward and high overcommitment were found to be the most important predictors for depression, suicidal ideation and suicide risk. Significant associations with depression, suicidal ideation and suicide risk were also revealed for time of study choice, general university entrance qualification grade, learning in a learning group, perceived peer competition and performance expectation from lecturers, as well as transparency of study requirements and transparency of examination requirements. Conclusions: The results of this study provide indications for the development of suitable prevention and intervention measures at veterinary medical schools to strengthen the mental health of veterinary students in Germany.

Adverse childhood experiences, positive childhood experiences, suicidal thoughts or behaviors and psychological distress among Kenyan youth-an exploratory analysis of the 2019 Kenya Violence Against Children and Youth Survey (VACS).

Adverse childhood experiences, positive childhood experiences, suicidal thoughts or behaviors and psychological distress among Kenyan youth-an exploratory analysis of the 2019 Kenya Violence Against Children and Youth Survey (VACS).

Personality Traits in the Patients of Depression with Suicidal Ideation

Introduction: Suicide is a major global health concern. Personality traits significantly influence depression with suicidal ideation, highlighting the need to explore their role for targeted, personalized treatment approaches. Objective: To assess the mean score of personality traits using Big Five Inventory 10 (BFI-10), in patients of depressive disorder with suicidal ideation presenting at the Department of Psychiatry and Behavioral Sciences, Jinnah Post Graduate Medical Centre (JPMC), Karachi. Study design: Cross sectional study. Study setting: Study was conducted at the Department of Psychiatry and Behavioral Sciences, JPMC, Karachi. Duration of study: 11th September, 2024 to 31st January, 2025. Subjects and methods: The Data was prospectively collected from patients after taking a written consent. One hundred patients who met the diagnostic criteria were included. A brief history was taken and demographic information was recorded after taking written informed consent. Data was analyzed by using SPSS 23.0. Effect modifiers were controlled through stratification to see the effect of these on the outcome variable. Post stratification independent t-test and one way ANOVA test was applied taking p-value of ≤0.05 as significant. Results: A total of 100 patients who met the inclusion and exclusion criteria were included in this study. Mean Age was 32 + 12 years. Mean scores of big Five personality traits were 5.94 ± 2.53, 3.62 ± 1.57, 4.02 ± 1.56, 4.68± 1.56, 4.96 ± 1.54, for Neuroticism, Extraversion, conscientiousness, openness to experience and Agreeableness respectively. Conclusion: Personality traits may significantly influence suicide risk, emphasizing the need for close monitoring and regular follow-up in vulnerable patients.

The hidden emotional costs of giving life: preserving donors' mental health and quality of life after living kidney donation.

Kidney living donation remains the best treatment available for kidney failure. Most living donors report positive personal outcomes, such as enhanced life satisfaction and personal growth. However, mental health challenges have also been documented. The study by Tahir, Aftab and Nabi (J Nephrol https://doi.org/10.1007/s40620-025-02217-5 , 2025) call the attention to a small subset of living donors who may experience significant depression symptoms and occasionally suicidal ideation after donation, particularly when the recipient dies or suffers severe graft failure with a return to dialysis. As observed in the previous studies, only donors whose recipients experienced negative outcomes reported mood alterations or life dissatisfaction (Menjivar et al., Transpl Int 31(12):1332-1344, 2018). These rare post-donation risk scenarios justify a careful mental evaluation to identify psychological vulnerabilities or a history of difficulties in managing and coping with stressful situations. These adverse outcomes appear more likely in donors with pre-donation physical and/or psychological vulnerabilities, in those with a complicated surgical recovery after donation, and in cases where recipients experience poor physical or psychological outcomes. Moreover, cases of graft failure or recipient death might significantly increase donor's likelihood of depression and anxiety, Despite the generally low incidence of psychosocial problems after donation, there have been calls for a more structured and routine follow-up assessment to further mitigate risks and ensure equitable mental health safety for all kidney donors.

A Hybrid Deep Learning Framework and Dwarf Mangoose Optimized Layers for an Effective Depression Classification

Depression is considered to be one of the dangerous diseases that affects physical state of human and even causes the fatal end to the patients. The depression leads to the anxiety disorders, bipolar disorders and at the same time may hit the person’s mind set to the suicide thoughts. Hence it is considerably demanding task to recognise the individuals with mental conditions. Traditionally, depression detection was done through patient’s interview and PHQ scores, but these traditional methods produce the accuracy which has very little effect on the diagnosis and treatment process. With the advent of machine (ML) and deep learning (DL) models, depression detection has reached its new dimensional path but still diagnosis performance and computational overhead remains to be real bottleneck for achieving its own strength of classification and early diagnosis. To solve this aforementioned problem, this research paper proposed hybrid ensemble of deep learning models and optimized training networks. Proposed framework consists of three components: first, adaptive dilated convolutional networks in which the model is trained with text and audio features, third is Bi-GRU Networks a finally the learning layers are optimized by DwarfMangoose Model to attain the better classification of depressions. The recommended model is examined and evaluated by utilizingDAIC-WOZ database and performance metrics such as accuracy, precision, recall, specificity and F1-score are measured and examined with the varied state-of-art learning procedures. The results demonstrate the recommended model has provided the optimal solution in detecting the depressions and produced the accuracy of 0.98, precision of 0.972, recall of 0.98, specificity of 0.98 and F1-score of 0.987 respectively. Experimental findings have proved that the proposed model has produced the promising results that improvises the clinical treatment and overcomes the fatal fears of the patients caused by the depression.

Predicting Suicidal Ideation Among Native American High Schoolers in California

Introduction Suicide is the leading cause of non-accidental death for Native American young people ages 15-24. Alarmingly, suicide rates have continued to rise over the past decade despite ongoing prevention efforts. This shortcoming has urged some scholars to (re)examine dominant theoretical models to better direct suicide prevention efforts in tribal communities. Method Using Indigenous Wholistic Theory, this study used an algorithmic approach to identify a broader set of factors associated with suicidal ideation among Native American high school students in California (n = 2,609). Data were drawn from the 2019–2020 California Healthy Kids Survey, a statewide school-based dataset. Lasso penalized regression was employed to select the most predictive variables for suicidal ideation from a set of 17 candidate factors. Results Ten predictors were retained in the final model: depressive symptoms; school-based victimization; sexual and gender minority status; lifetime use of alcohol, vapes, and cannabis; breakfast consumption; access to alcohol and other drugs; and parent education level. Conclusion A combination of factors spanning individual, emotional-social, mental-political, and physical-economic domains predicted individualized risk for experiencing suicidal ideation. These findings underscore the need to move beyond psycho-centric models and toward more comprehensive understandings of suicide-related behavior among Native American youth.

Predictors of suicide attempt among subjects who were previously exposed to sexual abuse.

Child sexual abuse is a condition that can affect the victim's life in every period and is closely related to physical and mental problems. One of the important consequences of child sexual abuse is suicide. The idea that there is a close relationship between child sexual abuse and suicidal ideation and attempts is widely accepted in the literature, but this relationship is quite complex. In this study, we investigated the factors associated with suicide risk in children and adolescents who were victims of sexual abuse. Two groups were formed: participants who were sexually abused and attempted suicide, and participants who were sexually abused and did not attempt suicide. They were evaluated in terms of anxiety, depression, posttraumatic stress disorder, borderline personality traits, impulsivity, traumatic experiences, and perceived social support using scales. The total scores of anxiety-depression, posttraumatic-stress-disorder, impulsivity, traumatic experiences, and borderline personality traits scales were found to be significantly higher, while the perceived social support scale score was found to be significantly lower in the group who attempted suicide. Our findings revealed factors associated with suicide attempts in child and adolescent who were sexual abuse victims. Taking these factors into account when evaluating victims of sexual abuse will provide early intervention to high risk patients.

The relationship between body roundness index (BRI) and suicidal ideation: evidence from NHANES 2013–2018

ImportanceEmerging research suggests a complex interplay between physical health metrics and mental health outcomes, including suicidal ideation. The body roundness index (BRI), a novel measure of body size, may offer insights into this relationship. This study seeks to investigate the intricate connection between BRI and suicidal ideation in a sample that reflects the entire U.S. population-working to validate the potential of BRI as a predictor of suicidal ideation.MethodsData from the NHANES spanning 2013 to 2018 was used in this cross-sectional study to analyze a sample of 14,058 participants. BRI was calculated based on height and waist circumference measurements. Suicidal ideation was assessed using the Mental Health-Depression Screener Questionnaire ninth question. To investigate potential non-linear relationships between BRI and suicidal ideation, we employed generalized additive models and smooth curve fitting, and used ROC curves to compare the predictive ability of BMI and BRI for suicidal ideation. Subgroup analyses and interaction tests were utilized to study the moderating effects of categorical covariates.ResultsMultiple logistic regression analysis revealed a significant positive correlation between increased BRI and heightened suicidal ideation, with a nonlinear pattern persisting even after adjustment for covariates. This nonlinear relationship was reinforced by a sharp increase in the prevalence of suicidal ideation when the BRI exceeded 6.7. Based on ROC curve analysis, BRI demonstrates a slightly stronger predictive ability for suicide ideation compared to BMI. Subgroup analyses confirmed the relative robustness of this association across populations, including age, education and PRI, etc. However, the interaction between the two was influenced by gender, coronary artery disease and angina pectoris.ConclusionIn conclusion, our cross-sectional study reveals a significant positive correlation between increased BRI and heightened suicidal ideation, with a sharp increase in prevalence when BRI exceeds 6.7. It is recommended that appropriate BRI be maintained to minimize suicidal ideation.

Impact of Family Dysfunction on Suicidal Ideation in Students of the Faculty of Medicine and Surgery, URSE

The study at Universidad Regional del Sureste (URSE) examined suicidal ideation in fourth-year medical students over two academic periods. Using the Beck Suicidal Ideation Scale and Family Apgar, it found a prevalence of 5.5% in 2023-2024 and 7.9% in 2024-2025. Suicidal ideation is identified as a global public health issue, worsened by the intense academic and emotional demands of medical training. This study did not find a significant correlation between family dysfunction and suicidal ideation. However, it is essential to recognize that family dysfunction, in combination with factors such as stress, depression, and substance use, may increase the risk of suicide in other populations. This reinforces the need for comprehensive interventions that include emotional and psychological support programs, healthy academic environments, and the promotion of open discussions about mental health. These initiatives aim to reduce the stigma around seeking help and equip future physicians with tools for their holistic well-being.

The moderating role of depressive symptoms in the relationship between earthquake exposure severity and suicidal ideation among survivors of the February 6 to 7 Kahramanmaraş Earthquakes, Turkiye.

Suicidal ideation (SI) is frequently observed in individuals exposed to traumatic events like earthquakes, with its intensity being influenced by factors such as the severity of earthquake exposure and depression. Therefore, identifying the key factors that contribute to suicidal ideation in individuals severely affected by earthquakes and those who have suffered significant harm is essential for minimizing the trauma's impact through targeted psychosocial interventions. This study aims to identify the risk factors contributing to SI and examine whether depressive symptoms moderate the relationship between the severity of earthquake exposure and lifetime suicidal ideation among survivors of the February 6 to 7, 2023, earthquake in Turkiye. This study was carried out with 186 earthquake survivors (women: 55.9% and men: 44.1%). The study design was cross-sectional and included self-report assessments. The Earthquake Experience Questionnaire (EEQ), the Anxiety Subscale of the Depression Anxiety Stress Scale-21 (DASS-21), and the Multidimensional Scale of Perceived Social Support (MSPSS) were used in the study. A significant interaction was observed only between depressive symptoms and earthquake experience in predicting lifetime SI. Among individuals with moderate to high levels of depression, SI decreased as the severity of earthquake experience increased. The findings suggest that positive psychological processes, such as post-traumatic growth, may reduce SI. However, depression remains a significant risk factor, highlighting the need for effective treatment and psychological recovery support after trauma.

Prospective associations of insomnia and nightmares with suicidal behavior among primary care patients.

Insomnia and nightmares have both been associated with suicide risk and are both known to be commonly reported in a primary care setting. However, we are unaware of any studies examining the sleep-suicide relationship in the primary care setting. Clarifying these relationships could reveal important clues for improving suicide prevention efforts in primary care and other medical settings. Participants included 2,744 primary care patients recruited from six clinics located at five U.S. military installations. Participants completed measures of suicidal ideation, insomnia, and nightmares at baseline and suicidal ideation and suicide attempts were tracked at 6- and 12-month follow-up interviews. Of the 1,792 patients with follow-up data, 57 (3.2%) attempted suicide during the 12-month follow-up. Patients who attempted suicide during follow-up were more likely than patients who did not attempt suicide to have clinical insomnia and nightmares at least weekly. When adjusting for baseline suicidal ideation, clinical insomnia and nightmares at least weekly remained significant predictors of follow-up suicide attempts. Our findings suggest that insomnia and nightmares are accurate predictors of subsequent suicidal behavior among a primary care population and may offer positive predictive value for suicidal behavior over and above what can be provided by assessing suicidal ideation alone. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

The geographic identification of elevated suicide risk model: evaluating a method for examining suicide-related behaviors at the neighborhood level in Harris County, Texas

BackgroundThe 2024 National Strategy for Suicide Prevention has called for the development of community-based suicide prevention resources, and improved existing prevention efforts. In line with such efforts, Hill and colleagues developed the Geospatial Identification of Elevated Suicide Risk model that estimates the relative prevalence of adolescent suicide risk within specific geographical areas. The current study seeks to further evaluate and refine the model for use as a tool to evaluate risk and protective factors at the neighborhood level.MethodDrawing from multiple sources, data was collected detailing adolescent suicidal ideation, suicide attempts, suicide fatalities, and census tract characteristics. Utilizing data resulting from an initial pool of 74,883 suicidal ideation and attempt screens found in electronic health records, suicidal ideation and attempt rates were calculated, described, and mapped onto relevant census tracts via the Census Geocoder. Once mapped, a total of 1,098 census tracts were examined for criterion validity and minimum data evaluations.ResultsData indicate that rates of positive suicide risk screens are relatively normally distributed when using a minimum cell size of at least n = 5, with additional improvements at n = 10 screens per census tract. Of 48,928 records with completed screens and patient address data listed in the electronic health record, 44,776 addresses (91.5%) were matched to U.S. census tracts via the Census Geocoder database. When evaluating criterion validity, the simultaneous multivariate logistic regression revealed that the model did not fit well to the data, and suicide attempts and suicidal ideation only predicted 0.02% of the variance in the probability of suicide fatality. Finally, a classification tree revealed that a minimum of 10 data points were required to delineate between high and low-risk census tracts.ConclusionThe refined model may act as a helpful tool to evaluate neighborhood level risk and protective factors. Findings suggest a prevention-oriented, as opposed to risk prediction, approach to suicide risk management at the community level may be needed; such an approach would prioritize community connectedness, adequate mental health support services, and reduction of community-level risk factors (e.g., substance misuse), among others.

Effectiveness of Acceptance and Commitment Therapy for Suicidality: A Systematic Review and Meta-analysis.

Acceptance and commitment therapy (ACT) is recognized as an effective treatment for a variety of mental illnesses. Several meta-analyses have reported the efficacy of ACT in various mental and physical conditions, including depression, anxiety, and pain, but not for suicidality. This study aimed to determine the therapeutic effectiveness of ACT on suicidality through a systematic review and meta-analysis. Electronic databases such as PubMed, Embase, Scopus, and the Cochrane Library were searched for studies. The primary outcome measure was the effectiveness of ACT for suicidality which includes suicidal ideations and attempts. This systematic review and meta-analysis included eight studies, all of which were judged to have a high risk of bias. In the meta-analysis, the pooled standardized mean difference for suicidal ideations was 1.122 (95% confidence interval (CI) = 0.261 to 1.982). This meta-analysis suggests that ACT is effective for reducing suicidal ideation, but the high risk of bias across studies should be considered as a major limitation. Further well-designed studies are needed to confirm these findings.

Testing the interpersonal psychological theory of suicide in Turkish chronic pain patients: exploring the potential moderating role of self-construal

ABSTRACT This study aims to test the Interpersonal Psychological Theory of Suicide (IPTS) in Turkish chronic pain patients and examine the moderating role of interpersonal self-construal in the relationship between IPTS constructs and suicidal ideation severity. We used hierarchical regression analysis in a cross-sectional study involving 223 individuals with chronic pain conditions (195 females, 28 males; mean age = 40.08 years). Columbia Suicide Severity Rating Scale (C-SSRS) served as the criterion variable, with both general and pain-specific predictors as independent variables. After adjusting for other risk factors, perceived burdensomeness (PB) emerged as a significant predictor of suicidal ideation severity, while thwarted belongingness (TB) did not demonstrate similar predictive power. Contrary to the theory’s assumption, the interaction between PB and TB did not uniquely contribute to the severity of suicidal ideation. Furthermore, while a positive association was observed between pain threshold and acquired capability for suicide, this association did not hold for pain intensity and acquired capability. Additionally, interdependent self-construal did not moderate the relationship between IPTS constructs and suicidal ideation severity. Despite cultural variations, IPTS mechanisms operate similarly among Turkish chronic pain patients, underscoring its potential in understanding suicidality within this group. Ongoing research is needed to explore the interaction between cultural, psychological, and social factors influencing suicidal behavior among individuals with chronic pain.

Youth Suicide Prevention in the Emergency Department: Lethal Means Counseling 101.

Youth Suicide Prevention in the Emergency Department: Lethal Means Counseling 101.