ICAO Annex 16 regulations are used to certify the acoustic performance of subsonic transport aircraft. Each aircraft is classified according to the measured EPNL levels at specific certification locations along the approach and departure. By simulating this certification process, it becomes possible to identify all relevant parameters and assess promising measures to reduce the noise certification levels in compliance with the underlying ICAO regulations, i.e., allowable operating conditions of the aircraft. Furthermore, simulation is the only way to enable an assessment of novel technology and non-existing vehicle concepts, which is the main motivation behind the presented research activities. Consequently, the ICAO Annex 16 regulations are integrated into an existing noise simulation framework at DLR, and the virtual noise certification of novel aircraft concepts is realized at the conceptual design phase. The predicted certification levels can be directly selected as design objectives in order to realize an advantageous ICAO noise category for a new aircraft design, i.e., simultaneously accounting for the design and the resulting flight performance. A detailed assessment and identification of operational limits and allowable flight procedures for each conceptual aircraft design under consideration is enabled. Sensitivity studies can be performed for the relevant input parameters that influence the predicted noise certification levels. Specific noise sources with a dominating impact on the certification noise levels can be identified, and promising additional low-noise measures can be applied within the conceptual design phase. The overall simulation process is applied to existing vehicles in order to assess the validity of the simulation resultsfcompared to published data. Thereafter, the process is applied to some DLR low-noise aircraft concepts to evaluate their noise certification levels. These results can then be compared to other standard noise metrics that are typically applied in order to describe aircraft noise, e.g., SEL isocontour areas. It can be demonstrated that certain technologies can significantly reduce the noise impact along most of an approach or departure flight track but have only a limited influence on the noise certification levels and vice versa. Finally, an outlook of the ongoing developments is provided, in order to apply the new simulation process to supersonic aircraft. Newly proposed regulations for such concepts are implemented into the process in order to evaluate these new regulations and enable direct comparison with existing regulations.