At present, enterprises generally put scientific and technological innovation in the first place of their own strategic development. The core element of scientific and technological innovation is human resource. It is necessary to continuously inspire the vitality of scientific and technical personnel to improve the efficiency and benefit of innovation. From the realistic need of promoting incentive mechanism of scientific and technological innovation of enterprises, this article draws a conclusion that it’s necessary for State Grid Corporation of China to carry out incentive mechanism for scientific and technological personnel. On this basis, this article puts forward the ideas of incentive mechanism for scientific and technological personnel in State Grid Corporation of China, namely, growth incentives, spiritual incentives, economic incentives, environmental incentives, as well as selection model of incentive mechanism for scientific and technical personnel. Finally, on the basis of integrating the selection model of incentive mechanism, scientific and technological enterprises affiliated to State Grid Corporation of China are divided into four categories: technical research unit, soft scientific research unit, industrial unit, provincial (city) company. Meanwhile this article proposes different incentive strategies for the different subordinate enterprises. The contingent of scientific and technological personnel is the strategic core resource that relates to the development of scientific and technological innovation of companies in overall situation. And it’s an important support to successfully construct an international first-class science and technology innovation system. At present, there exist many problems in construction of talent team of scientific and technological innovation of State Grid Corporation of China. Such as lack of high-end technology leaders who have influence in scientific research at home and abroad, lack of systematic training and smooth career development channel, and incentive mean for innovation talents of scientific and technological is single. These all can‘t fully meet the development needs about the construction on two class of company. In order to build a world-class science and technology innovation system, it is necessary to further innovate the way of construction on scientific and technological personnel of the company. It’s necessary to speed up introduction, allocation, cultivation and incentive for scientific and technological talents. And it’s necessary to strive to establish a contingent of scientific and technological personnel that have the adequacy of the number of people, reasonable structure, good quality adopted to the world-class science and technology innovation system.