Growth Stunting Research Articles

Effectiveness of the upscaled use of a silver–ceramic (silver ionization) technology to disinfect drinking water in tanks at schools in rural India

ABSTRACT In many low- and middle-income countries, school children consume untreated water that has been pumped into storage tanks. The water is often of poor quality and consumption can cause gastrointestinal illnesses resulting in missed school days, growth stunting, and cognitive impairment. This study deployed a silver–ceramic technology (MadiDrop) to disinfect drinking water in school storage tanks. While silver ionization is effective at the household scale, relatively little research has been conducted on its effectiveness at the community scale. To address this gap, we assessed disinfection via MadiDrop at three schools that serve vulnerable populations in rural India. Tank inflow and treated outflow samples were tested for total coliforms (TCs) and Escherichia coli (EC). TC was significantly reduced overall and in two of three intervention tanks. Compared to the baseline, reductions in TC were significant in all three tanks and overall, while EC reductions were significant overall and in two of three tanks. TC reduction was negatively correlated with silver concentration and tank residence time, and silver concentrations were maintained below the drinking water quality guideline. While the intervention could be considered successful, several barriers and caveats are provided as are study limitations and areas for future research.

A systematic review of parenting and feeding practices, children’s feeding behavior and growth stunting in Asian countries

ABSTRACT This systematic review evaluates studies focusing on parenting and feeding practices, children’s feeding behavior, and growth stunting in Asian countries. Eight electronic databases were searched to screen studies published between Jan 2015 and May 2021. There were contradictory findings related to gender differences in growth stunting and factors that reinforce/facilitate or inhibit acquisition of optimum growth in children. Theme of parenting practices showed that time spent on childcare, traditional beliefs about child-care feeding and responsive feeding were also contributing factors. Amidst economic improvement, political, social changes, and worldwide execution of various nutritional programs, stunting continues to be relentlessly persistent and widespread in Asia. Undernutrition disturbs areas of the mind involved in reasoning, reminiscence, locomotor skills and also an adverse influence on the physical and psychological growth of children and ensuing learning capabilities. Stunted children have more anxiety and depression and lower self-esteem than non-stunted children. A public health strategy is required to: (i) properly examine stunting with time through collaborated efforts of community members and various sectors, (ii) tackle malnutrition with steps to enhance maternal nutrition during pregnancy, infant feeding practices and (iii) involvement of effective multi-sectoral partnership programs for management of stunting.

ROLE OF BIOTECHNOLOGY IN ABIOTIC STRESS TOLERANCE IN PLANTS

As population grows, abiotic stresses reduce plant growth and agricultural output, affecting global food security. Heat, cold, drought, salinity, and heavy metals affect crops. Heat stress from climate change disrupts cellular metabolism and lowers productivity. Tropical and subtropical crops suffer physiologically from cold stress. Climate variability affects drought, reducing crop output and germination. Salinity stunts growth and causes nutritional imbalances in big agricultural areas. Heavy metal buildup in soils threatens plant health. To overcome these problems, plants use osmotic adjustment, antioxidant defenses, and stress signaling pathways. CRISPR/Cas9 and other genetic engineering and molecular breeding methods may improve crop stress tolerance. Using omics technologies (genomics, transcriptomic, proteomics, and metabolomics) in breeding programs helps us understand stress tolerance processes and generate resilient crop types. This research is crucial for sustainable agriculture and global food security.

ANALYSIS OF STUNTING INCIDENTS IN TODDLER CHILDREN

Children who experience malnutrition, repeated infections, and inadequate psychosocial stimulation can result in impaired growth and development or stunting. There are still findings of cases of stunting in children under five, followed by the presence of malnourished children under five, where in 2023 there will be 243 stunting. There are many factors that cause stunting in the Puskesmas work area which causes problems in children, both health and growth and development. This research aims to determine the factors which is related to the incidence of stunting in children under five at the Megang Sakti Community Health Center, Musi Rawas Regency in 2024. The design of this research is quantitative research with a cross-sectional approach. The population in this study is the target group of children under five in 2023, totaling 32,561 respondents. The sample in this study consisted of 100 respondents. The sampling method uses purposive sampling technique, using the Slovin formula. Inclusion criteria are willingness to become a respondent by filling out a consent form. This research was carried out on March 10 - April 30 2024 at the Megang Hospital Health Center. Collecting primary data by interviews using questionnaires. Bivariate data analysis used the Chi-Square test and multivariate logistic regression. The results of the study showed that there was a relationship between maternal age (p value 0.02) and birth weight (p value 0.002) with the incidence of stunting in children under five at the Megang Sakti Community Health Center, Musi Rawas Regency. in 2024. The conclusion is that there is a relationship between age and birth weight with the incidence of stunting in children under five at the Megang Sakti Community Health Center, Musi Rawas Regency in 2024. The community health center should carry out continuous screening of children under five who are at risk of stunting and provide education on efforts to prevent stunting children, such as risk factors for stunting.

Anthropometric Measures Among Children and Teens With Classic 46,XX Congenital Adrenal Hyperplasia in Relation to Improvements in Diagnosis and Care

ObjectivesTo examine anthropometric changes of patients with classic 46,XX congenital adrenal hyperplasia (CAH) and matched referents; and 2) To investigate the impact of improvements in diagnosis and care on growth patterns in these patients by comparing changes in anthropometric parameters before and after CAH consensus guidelines. MethodsThis was a retrospective cohort study nested within 3 large integrated health-systems. Seventy-six patients with classic 46XX CAH and 1102 matched referents <21 years of age were identified. Anthropometric measurements including age-specific percentiles for height, weight, and body mass index were examined and compared between groups using linear mixed-effect models. Anthropometric trajectories were explored using latent class analyses. ResultsCAH patients had lower height percentiles than referents at all time points. Differences ranged from 10.7% to 28.4%. After age 5, differences in height were only significant among study participants born before the publication of CAH consensus guidelines. Latent class analyses of height detected a “gradual growth increase” pattern in 28% of CAH cases and only 4% of referents, and a “growth stunting” pattern was observed in 13% of CAH cases and 6% of referents. Height percentile measures did not differ in CAH patients with or without evidence of hormonal interventions (growth hormone and/or puberty blockers) used to increase adult height. ConclusionsThere is substantial heterogeneity in growth trajectories of CAH patients. Although stunting may affect CAH patients, advances in diagnosis and care improved anthropometric outcomes in this population. Understanding the disease- and therapy-related mechanisms that explain the different growth patterns requires additional research.

Growth Stunting and Nutritional Deficiencies among Children and Adolescents with Celiac Disease in Kuwait: A Case-Control Study.

This study aimed to assess the nutritional status of children and adolescents with celiac disease (CD) in Kuwait and investigate the nutritional deficiencies and sociodemographic factors associated with growth stunting in this population. This case-control study included 77 CD patients aged 3-18 years diagnosed with CD using IgA anti-tissue transglutaminase and duodenal biopsy and 33 healthy controls. Nutritional status was evaluated based on demographic and clinical characteristics, anthropometric measurements, and biochemical parameters. Univariate and multivariate logistic regression models were used to determine the association between CD and growth stunting. Approximately one-third (31%) of children with CD had stunted growth, 20.8% had a low body mass index for their age, and 5.2% had both growth stunting and wasting. Children with CD had higher odds of iron-deficiency anemia, vitamin D deficiency, anemia, and lower socioeconomic status. They were also younger and had decreased serum levels of vitamin D compared to the controls. These factors were all significantly associated with an increased risk of CD, collectively explaining over 50% of the risk. For growth stunting, lower education status among mothers, family income, and serum ferritin were identified as risk factors. A significant proportion of children and adolescents with CD had malnutrition, overt deficiencies, and impaired growth despite coherence with a gluten-free diet. Routine monitoring and targeted nutritional interventions are recommended for children and adolescents with CD to address malnutrition and growth stunting. Addressing socioeconomic disparities and enhancing maternal education may also help mitigate the risk factors.

H2O2 priming: Biostimulation, drought tolerance and DNA methylation profile with intergenerational impact in tobacco plant

H2O2 is a promising priming agent due to its role in stress-response pathways and in the regulation of gene expression. Several studies have shown that H2O2 elicitation improves stress responses. However, information regarding of the intergenerational stress memory of the H2O2 priming is limited. Therefore, in this study, we evaluated the stress memory induced by H2O2 priming in tobacco plants by testing hydric stress phenotypic response and changes in DNA methylation in the parental priming line and in the next generation. Priming consisted of three foliar applications of 200 mM H2O2 every 5 days on 4-week-old plants. DNA methylation profiling was performed by Whole Genome Bisulphite Sequencing (WGBS). Hydric stress challenge consisted of three conditions: control (100 %), moderate (40–45 %) and severe (20–25 %) stress according to the available water field capacity. Plant response to the challenge was evaluated by morphological, biochemical, and molecular attributes. The results showed that H2O2 priming displayed a biostimulant effect on vegetative and root development, preventing growth stunting under drought conditions. Plant antioxidant activity was enhanced, as reflected by the decrease in endogenous H2O2. In drought conditions, proline content, CAT activity and gene expression of CHS, PIP1 and AQP1 genes were enhanced in the primed-plants (H), their progeny (F1), and the primed-progeny group (FH). DNA methylation profile revealed 795 differentially methylated cytosines (DmCs) in the progeny, with 89 associated with genes involved in cellular response to environmental stimuli. An interaction network highlighted stress response with flavoreductase enzyme as central interaction node, and in the second layer the Repressor of Silencing 1 (ROS1) gene. Thus, the findings suggest that H2O2 priming may induce intergenerational memory, presenting a potentially cost-effective strategy in stress management in agriculture.

Protection from environmental enteric dysfunction and growth improvement in malnourished newborns by amplification of secretory IgA

Environmental enteric dysfunction (EED) is a condition associated with malnutrition that can progress to malabsorption and villous atrophy. Severe EED results in linear growth stunting, slowed neurocognitive development, and unresponsiveness to oral vaccines. Prenatal exposure to malnutrition and breast feeding by malnourished mothers replicates EED. Pups are characterized by deprivation of secretory IgA (SIgA) and altered development of the gut immune system and microbiota. Extracellular ATP (eATP) released by microbiota limits T follicular helper (Tfh) cell activity and SIgA generation in Peyer's patches (PPs). Administration of a live biotherapeutic releasing the ATP-degrading enzyme apyrase to malnourished pups restores SIgA levels and ameliorates stunted growth. SIgA is instrumental in improving the growth and intestinal immune competence of mice while they are continuously fed a malnourished diet. The analysis of microbiota composition suggests that amplification of endogenous SIgA may exert a dominant function in correcting malnourishment dysbiosis and its consequences on host organisms, irrespective of the actual microbial ecology.

Identification of a New B-Cell Epitope on the Capsid Protein of Avian Leukosis Virus and Its Application.

Avian leukosis virus (ALV) is an avian oncogenic retrovirus that can impair immunological function, stunt growth and decrease egg production in avian flocks. The capsid protein (P27) is an attractive candidate for ALV diagnostics. In the present study, a new hybridoma cell (1F8) stably secreting an anti-P27 monoclonal antibody (mAb) was developed. The mAb exhibited a high affinity constant (Ka) of 8.65 × 106.0 L/mol, and it could be used for the detection of ALV-A/B/J/K strains. Moreover, a total of eight truncated recombinant proteins and five synthetic polypeptides were utilized for the identification of the B-cell epitopes present on P27. The results revealed that 218IIKYVLDRQK227 was the minimal epitope recognized by 1F8, which had never been reported before. Additionally, the epitopes could strongly react with different ALV subgroup's specific positive serum and had a complete homology among all the ALV subgroups strains. Finally, a new sandwich ELISA method was created for the detection of ALV antigens, demonstrating increased sensitivity compared to a commercially available ELISA kit. These results offer essential knowledge for further characterizing the antigenic composition of ALV P27 and will facilitate the development of diagnostic reagents for ALV.

Regulation of nitrogen metabolism by COE2 under low sulfur stress in Arabidopsis

The interplay between nitrogen and sulfur assimilation synergistically supports and sustains plant growth and development, operating in tandem to ensure coordinated and optimal outcomes. Previously, we characterized Arabidopsis CHLOROPHYLL A/B-BINDING (CAB) overexpression 2 (COE2) mutant, which has a mutation in the NITRIC OXIDE-ASSOCIATED (NOA1) gene and exhibits deficiency in root growth under low nitrogen (LN) stress. This study found that the growth suppression in roots and shoots in coe2 correlates with decreased sensitivity to low sulfur stress treatment compared to the wild-type. Therefore, we examined the regulatory role of COE2 in nitrogen and sulfur interaction by assessing the expression of nitrogen metabolism-related genes in coe2 seedlings under low sulfur stress. Despite the notable upregulation of nitrate reductase genes (NIA1 and NIA2), there was a considerable reduction in nitrogen uptake and utilization, resulting in a substantial growth penalty. Moreover, the elevated expression of miR396 perhaps complemented growth stunting by selectively targeting and curtailing the expression levels of GROWTH REGULATING FACTOR 2 (GRF2), GRF4, and GRF9. This study underscores the vital role of COE2-mediated nitrogen signaling in facilitating seedling growth under sulfur deficiency stress.

EDUKASI DAMPAK PERNIKAHAN DINI DI DESA RIDOMANAH

Early marriage is a marriage that is carried out by early childhood or has not reached the age allowed for marriage. In law, marriage is allowed when you reach the age of 19 years. However, there are still many people who practice early marriage, especially rural communities. Early marriage has many impacts, one of which is the failure of child growth and development or stunting. In this community service, the goal is to prevent early childhood marriage and stunting in Ridomanah village. In this activity, the subject is students of SMPN 2 Cibarusah, the implementation method is community education with socialization of the impact of early marriage. Based on the percentage of pre-test and post-test results, student knowledge has increased significantly, from 64.20% to 85.40%. This socialization activity on the impact of early marriage at SMPN 2 Cibarusah is quite effective and successful in increasing students' knowledge about the impact of early marriage.

An oxylipin signal confers protection against antifungal echinocandins in pathogenic aspergilli

Aspergillus fumigatus is the leading causative agent of life-threatening invasive aspergillosis in immunocompromised individuals. One antifungal class used to treat Aspergillus infections is the fungistatic echinocandins, semisynthetic drugs derived from naturally occurring fungal lipopeptides. By inhibiting beta-1,3-glucan synthesis, echinocandins cause both fungistatic stunting of hyphal growth and repeated fungicidal lysis of apical tip compartments. Here, we uncover an endogenous mechanism of echinocandin tolerance in A. fumigatus whereby the inducible oxylipin signal 5,8-diHODE confers protection against tip lysis via the transcription factor ZfpA. Treatment of A. fumigatus with echinocandins induces 5,8-diHODE synthesis by the fungal oxygenase PpoA in a ZfpA dependent manner resulting in a positive feedback loop. This protective 5,8-diHODE/ZfpA signaling relay is conserved among diverse isolates of A. fumigatus and in two other Aspergillus pathogens. Our findings reveal an oxylipin-directed growth program—possibly arisen through natural encounters with native echinocandin producing fungi—that enables echinocandin tolerance in pathogenic aspergilli.

Biocultural and social determinants of ill health and early mortality in a New Mexican paediatric autopsy sample.

Hispanic children have higher odds of growth stunting than non-Hispanic White children. Native American children die younger and have higher odds of respiratory diseases and porous lesions than Hispanic and non-Hispanic Whites. Rural/urban location does not significantly impact age at death, but housing type does. Individuals who lived in trailers/mobile homes had earlier ages at death. When intersections between housing type and housing location are considered, children who were poor and from impoverished areas lived longer than those who were poor from relatively well-off areas. Children's health is shaped by factors outside their control. The children included in this study embodied experiences of social and ELS and did not survive to adulthood. They provide the most sobering example of the harm that social factors (structural racism/discrimination, socioeconomic, and political structures) can inflict.

Colonization during a key developmental window reveals microbiota-dependent shifts in growth and immunity during undernutrition

BackgroundChildhood undernutrition is a major global health challenge with devastating lifelong consequences. Linear growth stunting due to undernutrition has been linked to poor health outcomes, and mothers who experience growth stunting in childhood are more likely to give birth to stunted children later in life. Based on these findings, we hypothesized that intergenerational colonization of mice with microbiota from human donors with undernutrition may recapitulate certain immune and growth changes observed in this disorder.ResultsTo test this hypothesis, we developed a gnotobiotic murine model of undernutrition using microbiota from human infants with healthy or stunted growth trajectories. Intergenerational colonization with microbiota derived from children with growth stunting lead to less linear growth and the development of immune features of undernutrition and enteropathy, including intestinal villus blunting, lower liver IGF-1 and accumulation of intraepithelial lymphocytes and plasma cells in the small intestine. In contrast, colonization after weaning lead to fewer host phenotypic changes between these distinct microbial communities.ConclusionsThese results are broadly consistent with previous findings demonstrating that exposure of the immune system to microbial products during the weaning phase is a critical determinant of later life immune function. Overall, our results suggest intergenerational colonization with human microbiota samples is a useful approach with which to investigate microbiota-dependent changes in growth and immunity in early life. Murine models that capture the intergenerational and multifactorial nature of undernutrition are critical to understanding the underlying biology of this disorder.7T5ZN13mtZ1d8dLkaKDJxvVideo

Small Intestine Bacterial Overgrowth is associated with increased Campylobacter and epithelial injury in duodenal biopsies of Bangladeshi children.

Small intestine bacterial overgrowth (SIBO) has been associated with enteric inflammation, linear growth stunting, and neurodevelopmental delays in children from low-income countries. Little is known about the histologic changes or epithelial adherent microbiota associated with SIBO. We sought to describe these relationships in a cohort of impoverished Bangladeshi children. Undernourished 12-18-month-old children underwent both glucose hydrogen breath testing for SIBO and duodenoscopy with biopsy. Biopsy samples were subject to both histological scoring and 16s rRNA sequencing. 118 children were enrolled with 16s sequencing data available on 53. Of 11 histological features, we found that SIBO was associated with one, enterocyte injury in the second part of the duodenum (R = 0.21, p = 0.02). SIBO was also associated with a significant increase in Campylobacter by 16s rRNA analysis (Log 2-fold change of 4.43; adjusted p = 1.9 x 10-6). These findings support the growing body of literature showing an association between SIBO and enteric inflammation and enterocyte injury and further delineate the subgroup of children with environmental enteric dysfunction who have SIBO. Further, they show a novel association between SIBO and Campylobacter. Mechanistic work is needed to understand the relationship between SIBO, enterocyte injury, and Campylobacter.

STUNTING PREVENTION STRATEGY BY IMPROVING THE NUTRITIONAL STATUS OF TODDLER : A SYSTEMATIC REVIEW

Background: Globally, there has been progress in lowering the rates of linear growth stunting and chronic undernutrition in children under five years old, however many areas still have high rates. Aims : This systematic review is to review stunting prevention strategy with improving status of nutrition in toddler. Methods: This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. Result: In the PubMed database, the results of our search brought up 691 articles, whereas the results of our search on SAGEPUB brought up 2026 articles, our search on SCIENCE DIRECT brought up 4136 articles. The results of the search conducted for the last year of 2014 yielded a total 430 articles for PubMed, 776 articles for SAGEPUB and 2307 articles for SCIENCE DIRECT. In the end, we compiled a total of 8 papers, 6 of which came from PubMed, 1 of which came from SAGEPUB and 1 of which came from SCIENCE DIRECT. We included eight research that met the criteria. Conclusion: In summary, stunting must be managed in order to protect children from its harmful effects. To do this, a variety of linked parties must contribute to the effort. Improving the mother's responsive stimulation and health education might be the first step in improving the nutritional and cognitive state of the kid.

Substrate Matters: Ionic Silver Alters Lettuce Growth, Nutrient Uptake, and Root Microbiome in a Hydroponics System.

Ionic silver (Ag+) is being investigated as a residual biocide for use in NASA spacecraft potable water systems on future crewed missions. This water will be used to irrigate future spaceflight crop production systems. We have evaluated the impact of three concentrations (31 ppb, 125 ppb, and 500 ppb) of ionic silver biocide solutions on lettuce in an arcillite (calcinated clay particle substrate) and hydroponic (substrate-less) growth setup after 28 days. Lettuce plant growth was reduced in the hydroponic samples treated with 31 ppb silver and severely stunted for samples treated at 125 ppb and 500 ppb silver. No growth defects were observed in arcillite-grown lettuce. Silver was detectable in the hydroponic-grown lettuce leaves at each concentration but was not detected in the arcillite-grown lettuce leaves. Specifically, when 125 ppb silver water was applied to a hydroponics tray, Ag+ was detected at an average amount of 7 μg/g (dry weight) in lettuce leaves. The increase in Ag+ corresponded with a decrease in several essential elements in the lettuce tissue (Ca, K, P, S). In the arcillite growth setup, silver did not impact the plant root zone microbiome in terms of alpha diversity and relative abundance between treatments and control. However, with increasing silver concentration, the alpha diversity increased in lettuce root samples and in the water from the hydroponics tray samples. The genera in the hydroponic root and water samples were similar across the silver concentrations but displayed different relative abundances. This suggests that ionic silver was acting as a selective pressure for the microbes that colonize the hydroponic water. The surviving microbes likely utilized exudates from the stunted plant roots as a carbon source. Analysis of the root-associated microbiomes in response to silver showed enrichment of metagenomic pathways associated with alternate carbon source utilization, fatty-acid synthesis, and the ppGpp (guanosine 3'-diphosphate 5'-diphosphate) stringent response global regulatory system that operates under conditions of environmental stress. Nutrient solutions containing Ag+ in concentrations greater than 31 ppb in hydroponic systems lacking cation-exchange capacity can severely impact crop production due to stunting of plant growth.

Behavioral and neurophysiological effects of buspirone in healthy and depression-like state juvenile salmon.

A proportion of farmed salmon in seawater show a behaviorally inhibited, growth stunted profile known as a depression-like state (DLS). These DLS fish are characterized by chronically elevated serotonergic signaling and blood plasma cortisol levels and the inability to react further to acute stress, which is suggestive of chronic stress. In this study, we characterize the neuroendocrine profile of growth stunted freshwater parr and confirm that they show a DLS-like neuroendocrine profile with a blunted cortisol response and no serotonergic increase in response to acute stress. Furthermore, we attempted to reverse this DLS-like profile through pharmacological manipulation of the serotonin (5-HT) system with buspirone, an anxiolytic medication that acts as a serotonin receptor agonist (i.e., decreases serotonergic signaling). We found that while buspirone decreases anxiolytic-type behavior in healthy fish, no quantifiable behavioral change was found in DLS-like fish. However, there was a physiological effect of diminished basal serotonergic signaling. This suggests that at the physiological level, buspirone appears to reverse the neuroendocrine DLS profile. With a deeper understanding of what causes DLS profiles and growth stunting in juvenile fish, steps can be taken in terms of husbandry to prevent repeated stressors and the formation of the DLS profile, potentially reducing losses in aquaculture due to chronic stress.

Algorithm for Growth Evaluation in Juvenile Idiopathic Arthritis.

Juvenile Idiopathic Arthritis (JIA) includes a range of inflammatory conditions that exhibit chronic arthritis with various clinical presentations. The disease's heterogeneity leads to different impacts on children's health, both short and long-term. Compromised growth, seen as growth retardation and delayed puberty, is a common complication in children with JIA, severely impacting their quality of life. This impairment is linked to disease duration and activity, with severe cases in systemic and polyarticular subtypes. Literature reports growth retardation incidence from 8% to 41%, but data on pubertal impairment is lacking. Growth in children is influenced by systemic and local mechanisms. Chronic inflammation, prolonged glucocorticosteroid (GCS) use, and nutritional issues contribute to growth stunting and pubertal delays. Chronic inflammation in JIA flattens growth curves, while steroid treatment impairs growth and causes weight gain. Disruption of the GH/IGF1 axis is known, but data on systemic hormonal resistance in JIA are insufficient. Optimizing JIA treatment, including biological therapies, is expected to improve growth velocity and reduce long-term impacts by better disease control and reduced GCS doses. Thyroid function also influences growth and puberty, but comprehensive studies on thyroid involvement in JIA are lacking. Given the early onset of chronic inflammatory consequences, preventive auxological screening measures are necessary for children with JIA. Early detection of developmental disorders can enhance therapeutic management. This article summarizes information from a cohort study on growth in children with JIA and proposes a diagnostic algorithm for clinical use.

The correlation between oral health and stunting in children: A literature review

Background: Growth stunting refers to a condition in which children have a lower stature compared to their classmates, as determined by the World Health Organization's child growth standard assessment. This disorder can impact the growth of the brain and other body components, including the oral cavity, leading to effects on oral hygiene and general oral health. The objective of this study is to establish the relationship between stunting and dental and oral health in children. There is a considerable body of scientific research that leans in this way, and it appears that there is an association between growth retardation and dental health. According to the findings of this research, oral health was determined by the presence of oral hygiene, oral illness (dental caries), salivary flow rate, and salivary content. One of the risk factors for ECC is the presence of stunting. According to this study, there is a connection between stunting and ECC as well as moderate dental hygiene. Objectives: To review the correlation between oral health and stunting in children. Conclusion: There exists an association between growth stunting and dental health in children. The oral hygiene can be classified as moderate to poor based on the OHI-S test, and selected studies have identified a high plaque index. Furthermore, it was shown that children with growth stunting had a reduction in both salivary flow rate and the content of their saliva. Dental caries is the primary cause of oral illness, leading to a decline in oral health and is associated with development stunting in children.