Study Of Infective Endocarditis Research Articles

Role of 3D transoesophageal echocardiography in the study of infective endocarditis. Demonstration in a case collection.

Infective endocarditis (IE) is a condition that predominantly affects native or prosthetic heart valves, which is currently on the rise due to the increase in invasive cardiology procedures, such as the utilization of cardiac implantable electronic devices and transcatheter interventions. The recommended imaging tests for diagnosis are 2D transthoracic echocardiography (2D TTE) and 2D transoesophageal echocardiography (2D TOE). However, these modalities present limitations in detecting vegetations and estimating their dimensions. These disadvantages can be overcome by 3D transoesophageal echocardiography (3D TOE), particularly with the multiplanar reconstruction tool, which allows for the visualization of infinite valve planes, thus optimizing the detection of lesions and precise measurements. Furthermore, the volume rendering provides insight into the anatomical relationships between lesions, which is particularly useful for surgical planning. In this review, we aim to discuss the role of this recent imaging modality in the diagnosis, prognosis, and therapeutic of IE. Finally, we present a collection of images that illustrate the use of 3D TOE tools.

Diagnostic accuracy of ICD code versus discharge summary-based query for endocarditis cohort identification.

Studies of infective endocarditis (IE) have relied on International Classification of Disease (ICD) codes to identify cases, a method vulnerable to misclassification. Clinical narrative data could offer greater accuracy and richness to cohort identification. We evaluated two algorithms: 1.a standard query of ICD-9/10 billing codes, with or without procedure codes for echocardiogram and2.a text query of discharge summaries (DS) that selected on the term “endocarditis” in fields headed by “Discharge Diagnosis” or “Admission Diagnosis” or similar.Further coding extracted valve involved and organism responsible if present. All cases were chart reviewed using pre-specified criteria. Positive predictive value (PPV), sensitivity and specificity were calculated. The ICD-based query identified 612 individuals from July 2015 to July 2019 who had a hospital billing code for infective endocarditis; of these, 534 had an echocardiogram. The DS query identified 387 cases. PPV for the DS query was 84.5% (95% CI 80.6%, 87.8%) compared with 72.4% (95% CI 68.7%, 75.8%) for ICD only (P < .001) and 75.8% (95% CI 72.0%, 79.3%) for ICD + echo queries (P = .002). Sensitivity was 75.9% for DS query and 86.8% to 93.4% for ICD queries (P < .02 for these comparisons). Specificity was high for all queries >94%. The DS query also yielded valve data (prosthetic, tricuspid, aortic, etc) in 60% and microbiologic agent in 73% of identified cases with an accuracy of 94% and 90%, respectively when assessed by chart review. Compared with ICD-based queries, text-based queries of discharge summaries have the potential to improve precision of IE case ascertainment and extract key clinical variables.

Clinical study of infective endocarditis in children: a 3 years experience from MGM Hospital, Warrangal

Background: The impact of endocarditis in childhood accompanies many cardio-vascular disorders. Infective endocarditis (IE) is the most frequently occurring form of endocardium inflammation. Prevailing among the agents are Str. Viridans, Str. Haemoliticus, Staph. Aureus, Staph Epidermidis, Enterococcus, etc. Objective: This study will explore the outcome of children diagnosed with infective endocarditis for a better guidance in management. Methods: This was a prospective study from warrangal from January 2013 to December 2015. 50 patients with definite IE based on modified Duke’s criteria were recruited into the study. Clinical presentation, risk factors, echocardiography and outcome were obtained. Results: A total of 50 IE patients were included within the study. The mean age was 6 ± 5.45. Most patients (80.39%) were diagnosed within the first week of admission. Staphylococcus aureas was the most common pathogen (38%) and the mitral valve was predominantly affected (68%). Complication were common and in hospital mortality remains high (27.3%). Conclusions: Mortality remains relatively high in children with infective endocarditis. The most common complication is cardiac deficiency (70%), and pleuropericardial effusions and lung embolism

Prospective study of infective endocarditis in a tertiary care centre in Kerala: Prognostic role of baseline ESR Vs. CRP

Prospective study of infective endocarditis in a tertiary care centre in Kerala: Prognostic role of baseline ESR Vs. CRP

Microbiological Profile, Echocardiographic Characteristics and Early Results of Infective Endocarditis: A Review of 194 Cases at a Tertiary Care Center in Turkey

OP-184 We aimed to evaluate microbiological profile, echocardiographic characteristics and early results of infective endocarditis (IE) in a tertiary university hospital. In this retrospective case study of infective endocarditis (IE), the data of patients hospitalized for definite IE in our

Study of infective endocarditis in Alexandria main university hospitals

Abstract Objectives To describe the incidence, clinical characteristics, microbiological profile and in-hospital outcome of infective endocarditis (IE) in our center. Methods A prospective study that was conducted on 50 consecutive patients admitted to our cardiology department diagnosed as Duke definite IE. The study was conducted for a period of one year and started on the 1st of September 2009 till the end of August 2010. All patients were subjected to detailed history taking, clinical examination, blood culture and echocardiography. Results The study was carried out on 29 males (58%) and 21 females (42%) with a mean age of 33 years. The mean duration of delay from onset of symptoms till diagnosis was 54 days. Native valve endocarditis was found in 34 patients (68%). Blood cultures were positive in 27 patients (54%). Staphylococci were the prevalent microorganisms (52%). In-hospital events included: heart failure in 29 patients (58%), systemic embolization in 13 patients (26%), para-valvular abscess in 8 patients (16%), septic pulmonary emboli in 7 patients (14%), dehiscence of prosthetic valves in 5 patients (10%) and renal failure in 2 patients (4%). Surgical intervention was indicated in 41 patients (82%). Only 16 patients (39%) had early surgical intervention. In-hospital mortality was 22%. However, the mortality rate improved in the patients who had undergone early surgical intervention (18.75% versus 32%). Conclusions Infective endocarditis remains a major health problem. It carries high in-hospital events with a high mortality rate. Delayed diagnosis of the disease and culture negative IE are common. Staphylococci are the prevalent microorganisms. Early surgical intervention improves survival.

A 10-year Retrospective Study of Infective Endocarditis at a University Hospital with Special Regard to the Timing of Surgical Evaluation in S. viridans Endocarditis

A total of 154 episodes of infective endocarditis (IE) in 149 patients were studied retrospectively with special regard to the major aetiological groups and the surgical evaluation. There were 136 episodes of native valve endocarditis (NVE) (88%) and 18 episodes of prosthetic valve endocarditis (PVE) (12%). Three major groups of NVE crystallized: Streptococcus viridans in 37 (27%), Staphylococcus aureus in 39 (29%) and culture negative IE in 28 (21%) episodes. In these groups surgery during the active phase was required in 41, 28 and 18%, respectively. At the operation myocardial abscess was found in as many as 7/15 cases with S. viridans, but in only in 3/11 cases with S. aureus and 1/5 cases with culture negative IE. The mean duration of preoperative antibiotic treatment was 34 d. This long period of unsuccessful pharmacotherapy, preceded by a mean of 47 d from start of symptoms to admission to hospital, has probably resulted in the high frequency of myocardial abscess in S. viridans NVE. Surgical evaluation should be considered when fever persists beyond 10 d of adequate treatment, even in the absence of clinically apparent complications. Among the PVE episodes, 11/18 were managed with pharmacological treatment alone. Uncomplicated PVE may thus often be successfully treated with antibiotics alone.

36.感染性心内膜炎(IE)の心エコーについての検討

36.感染性心内膜炎(IE)の心エコーについての検討

36.感染性心内膜炎(IE)の心エコーについての検討(第23回秋季学術大会一般研究発表予稿)

36.感染性心内膜炎(IE)の心エコーについての検討(第23回秋季学術大会一般研究発表予稿)