In tight sandstone reservoirs, diagenesis has a significant impact on the development of reservoirs and pore structures. To clarify the effect of diagenesis on the pore structure of tight sandstone, 12 samples of the Yanchang Formation in the basin were studied based on experiments such as high-pressure mercury intrusion and low-temperature nitrogen adsorption. The diagenetic facies in the study area are divided into two categories: strong cementation facies of carbonate minerals and strong compaction facies of soft component minerals, which are relatively unfavorable diagenetic facies, and stable facies of felsic minerals and strong dissolution facies of feldspar minerals, which are dominant diagenetic facies. The pore structure of the Chang 63 reservoir in the study area has obvious fractal characteristics, with a fractal dimension D 1 greater than D 2 and a greater heterogeneity of large pore throats. Compared to compaction and cementation, dissolution has a stronger controlling effect on the pore structure of reservoirs. In tight sandstone reservoirs with low porosity and permeability, dissolution has a more important impact on reservoir transformation and development. The intensity of different types of diagenesis in the Chang 63 reservoir affects reservoir heterogeneity, and the level of the reservoir heterogeneity affects the complexity of reservoir pore structure. In tight sandstone reservoirs, cementation has a stronger controlling effect on the structural complexity of large pores, while dissolution has a stronger controlling effect on the structural complexity of small pores. The dissolution has a strong control effect on the physical properties of the reservoir. This study provides insights into the relationships among the diagenetic facies, reservoir quality, and pore structure of tight sandstone reservoirs. This study has reference significance for the exploration and development of tight oil in the research area.