Mining strip coal pillars left due to strip mining is important to resource-exhausted coal mines in eastern China. Backfilling mining is an effective means to mine strip coal pillars, which could decrease high stress and high energy release. However, materials with super-high water content were not widely applied in deeply isolated coal pillar mining due to lower strength characteristics and durability. In the paper, taking panel c8301 as engineering background, theoretical analysis, numerical simulation, and field monitoring were used to study the feasibility and application effect of the super-high-water backfilling technology in deep isolated coal pillar mining. The results showed that: (1) Panel c8301 is a strip-filling working face with insufficient mining on both sides, and the mining of the panel will trigger the rebalancing of the overlying rock structure on both sides, which increases the rock burst risk. (2) Simulation results indicate that the super-high-water filling method, in comparison to the traditional caving method, significantly reduces peak stress and elastic energy from 112.3 MPa to 4.6 × 106 J to 79.2 MPa and 2.23 × 106 J, respectively. This represents reductions of 29.6 % and 51.5 %, effectively mitigating the impact of mining activities on overburden movement. (3) On-site measurement data confirmed that the measured equivalent mining height was 1.25 m. The total number of microseisms and the amount of released energy decreased significantly, More specifically, three big energy release instances (>1.8 × 105 J) were recorded during the first roof weighting stage and panel in square meters. Super-high-water filling technology has achieved remarkable results in the mining of strip coal pillars and has significant application prospects.