Individual Stress Research Articles

Ocean Acidification and Sea Temperature Rise Affect the Queen Scallop Aequipecten opercularis (Linnaeus, 1758) in Captivity

Climate change poses risks to bivalves; thus, searching for resilient alternative species is crucial for sustainable fisheries. This study examines the impact of reduced pH and elevated temperature and their combined effects on the queen scallop Aequipecten opercularis in captivity. The results indicated that a low pH reduced its growth rates in both weight (0.03 ± 0.05 g/day) and length (0.06 ± 0.16 mm/day), as well as leading to decreases in meat yield (20.75 ± 2.75%) and the condition index (44.21 ± 7.19%). Conversely, elevated temperature resulted in an increased growth in length (0.07 ± 0.23 g/day), meat yield (21.57 ± 4.82%), and condition index (45.42 ± 7.35%). Combined stressors initially promoted growth but ultimately produced unsustainable outcomes, resulting in a reduced meat yield (18.28 ± 2.60%) and condition index (38.92 ± 8.23%), along with a peak mortality rate of 27%. These findings indicate that while A. opercularis can withstand individual stressors, exposure to simultaneous stressors may compromise its long-term viability in aquaculture systems.

Ameliorative impacts of carvacrol on DNA integrity, oxidative stress, and sperm quality in asthenozoospermic infertile individuals during cryopreservation.

Nowadays, the cryopreservation process can produce reactive oxygen species (ROS), which cause damage to the motility, cell membrane, and DNA integrity of sperm. This study is aimed at evaluating the impact of carvacrol, as a powerful antioxidant, on sperm features and improving oxidative stress throughout the cryopreservation procedure. In this prospective study, semen samples from 25 patients with asthenozoospermia were separated into three groups: fresh, freezing, and freezing + carvacrol (a dose of 100µM). The subsequent parameters were evaluated using standard methods in all three groups: sperm motility according to WHO criteria, sperm morphology using Papanicolaou staining, sperm viability with eosin-nigrosin staining, DNA integrity with acridine orange staining, levels of antioxidant enzymes (catalase, glutathione, and superoxide dismutase), total antioxidant capacity (TAC), and malondialdehyde (MDA) using ELISA. Also, DNA fragmentation was analyzed by the SDFA kit, and mitochondrial membrane potential (MMP) was assessed by rhodamine staining. Average sperm viability, motility, mitochondrial membrane potentiality, integrity of sperm membrane, and antioxidant enzyme levels are meaningfully reduced in the freezing group in contrast to the control group. The freezing group showed a meaningful rise in the mean MDA levels and DNA fragmentation compared to the control group. In the freezing group supplemented with carvacrol, a meaningful rise could be visible in mean percentages of viability, motility, and antioxidant enzyme levels, whereas mean levels of MDA and DNA fragmentation meaningfully declined in contrast to the freezing group. The results demonstrate that carvacrol, a potent antioxidant, offers significant protection against the loss generated by the freeze-thaw procedure, thereby improving sperm quality.

Photosynthetic efficiency and water retention in okra (Abelmoschus esculentus) contribute to tolerance to single and combined effects of drought and heat stress.

The co-occurrence of drought and heat significantly hampers plant productivity. Although their impacts are well studied, these studies have been based on the effects of individual stressors rather than their combined influence. Okra is crucial for food and nutritional security and livelihoods in many regions, yet it remains under-researched and unimproved. Okra has been proven to be sensitive to both drought and heat stress. This study employed a cost-effective phenotyping method to assess key traits characterising the diversity of okra morphophysiological responses to independent and interactive heat-drought stresses. This study aimed to understand okra responses to stress, identify stress-resilient traits, and characterise okra genotypes. We also addressed the need to examine interactive stress effects, which mirror real-world scenarios more accurately than single-stress studies. Sixty-three okra genotypes were subjected to heat, drought, or concurrent heat-drought stress at the seedling stage in improvised climate-controlled chambers. The germplasm exhibited significant variations in response to the various stresses. The broad-sense heritability was high (> 0.60) for traits such as chlorophyll content, plant biomass, performance indices, electrolyte leakage, and total leaf area. Drought stress alone had a more pronounced effect than heat stress alone, and the adverse impact was worsened under combined heat and drought stress. The interactive impact of drought and heat was more likely additive than antagonistic or synergistic. A positive and strong relationship was observed between photosynthetic efficiency parameters such as the Fv/Fm ratio, chlorophyll content, relative water index, and biomass parameters such as dry shoot weight. The 63 okra genotypes were classified into three distinct clusters, suggesting potential for future breeding efforts. Okra genotype considered to be tolerant or climate resilient (such as GH170, V1060831, GH174, V1060874, and GH106) to drought and heat, maintained enhanced photosynthetic efficiency and high internal water potential, possibly reducing osmotic and oxidative damage. This study revealed some mechanisms underlying the adaptation of okra genotypes to independent and combined heat and drought stress. The results provide a basis for breeding efforts to develop climate-resilient okra varieties.

Combining multiple stressors blocks bacterial migration and growth.

In nature, organisms experience combinations of stressors. However, laboratory studies use batch cultures, which simplify reality and focus on population-level responses to individual stressors.1,2,3,4,5 In recent years, bacterial stress responses have been examined with single-cell resolution using microfluidics.6,7,8,9,10,11,12 Here, we use a microfluidic approach to simultaneously provide a physical stressor (shear flow) and a chemical stressor (H2O2) to the human pathogen Pseudomonas aeruginosa. By treating cells with levels of flow and H2O2 that commonly co-occur in human host tissues,13,14,15,16,17,18 we discover that previous reports significantly overestimate the H2O2 levels required to block bacterial growth. Specifically, we establish that flow increases H2O2 effectiveness 50-fold, explaining why previous studies lacking flow required much higher concentrations. Using natural H2O2 levels, we identify the core H2O2 regulon, characterize OxyR-mediated dynamic regulation, and demonstrate that multiple H2O2 scavenging systems have redundant roles. By examining single-cell behavior, we serendipitously discover that the combined effects of H2O2 and flow block pilus-driven surface migration. Thus, our results counter previous studies and reveal that natural levels of H2O2 and flow synergize to restrict bacterial motility and survival. By studying two stressors at once, our research highlights the limitations of oversimplifying nature and demonstrates that physical and chemical stress can combine to yield unpredictable effects.

Ischemic Risks Induced by Larger Orthodontic Forces on Dental Pulp and Neuro-Vascular Bundle in Reduced Periodontium

Background/Objectives: There are few data about the ischemic risks induced by the large orthodontic forces during periodontal breakdown in dental pulp and neuro-vascular bundle (NVB) and none on the individual tissular stress distribution, despite their great importance for orthodontic treatment planning. Our aim was to assess, by a numerical analysis, the biomechanical behavior of dental pulp and the NVB during a simulated horizontal periodontal breakdown (1–8 mm), under 2–4 N of applied orthodontic forces and five movements (rotation, translation, tipping, intrusion, and extrusion). Additionally, the ischemic and degenerative-resorptive risks were assessed. Methods: The analysis involved 72 3D models of nine patients, totaling 720 simulations. The models were CBCT-based, having the second lower premolar and surrounding periodontium, and they suffered 1 mm of gradual horizontal periodontal breakdown (up to 8 mm loss). Results: Both forces displayed a similar qualitative stress distribution in all five movements, but with a quantitative increase (doubling of stress amounts for 4 N when compared with 2 N). The highest amounts of stress were displayed at 8 mm of periodontal loss, which is lower than the 16 KPa of the maximum hydrostatic pressure. The NVB stress was higher than the pulpal stress. Rotation was the most stressful, closely followed by tipping, intrusion, and extrusion. Conclusions: A total of 4 N of applied force seems to not induce any ischemic or degenerative-resorptive risks for healthy intact teeth, in up to 8 mm of periodontal breakdown. Intrusion and extrusion determined the highest visible tissular deformation in the NVB, with potential ischemic and resorptive-generative risks for previously traumatized/injured teeth (i.e., occlusal trauma). Rotation and translation (in particular) showed the highest coronal and radicular pulpal stress with potential ischemic and resorptive-generative risks for previously injured/traumatized dental pulp (i.e., direct-indirect pulp capping). It seems that 4 mm of periodontal breakdown could signal a clinical stress increase with potential ischemic and degenerative-resorptive risks for the previously traumatized/injured tissues.

Monocyte-lymphocyte ratio predicts cardiovascular diseases death in individuals with type 2 diabetes.

Previous studies have shown higher cardiovascular mortality risk with higher monocyte-lymphocyte ratio levels in general population. However, the levels of oxidative stress in individuals with type 2 diabetes are higher than those in the general population, which may affect the link between monocyte-to-lymphocyte ratio and cardiovascular disease deaths. And the association between the monocyte-to-lymphocyte ratio and mortality risk in people with type 2 diabetes still be unknown. This study aimed to investigate the prognostic significance of monocyte-to-lymphocyte ratio in type 2 diabetes. This analysis involved 2,954 individuals with type 2 diabetes from the National Health and Nutrition Examination Survey 1999-2010. The National Death Index records through December 31, 2019, was used to determine all-cause and cardiovascular mortality. The prognostic roles were determined using Cox regression models, restricted cubic spline analysis, and time-dependent receiver operating characteristic curve analysis. During an average follow-up period of 12.4 years, a total of 1,007 deaths occurred, while 252 were due to cardiovascular disease. An elevated monocyte-to-lymphocyte ratio level exhibited a significant dose-response relationship with an increased risk of all-cause mortality (1.34 [95% CI 1.12, 1.60] for all-cause mortality [Ptrend = 0.001]). The multivariable-adjusted HR was 1.81 (95% CI 1.25, 2.63) (Ptrend = 0.001) for cardiovascular mortality indicating a U-shaped relationship (Pnonlinear = 0.013). The results of this study indicate a U-shaped relationship between the monocyte-to-lymphocyte ratio and cardiovascular mortality in individuals with diabetes. Both very low and high monocyte-to-lymphocyte ratio monocyte-to-lymphocyte ratio values were found to be associated with increased cardiovascular mortality risk.

Validation and efficacy of a tele-yoga intervention for improving psychological stress, mental health and sleep difficulties of stressed adults diagnosed with long COVID: a prospective, multi-center, open-label single-arm study

The objective of this study was to validate and test the efficacy of a 16-week tele-yoga intervention for perceived stress, anxiety, depression, and insomnia in individuals who had had COVID-19 infection in the previous year, and had reported moderately high levels of psychological stress (PSS ≥14). 25 and 50-min versions of the program were developed. They were then validated using Lawshe’s content validity ratio after obtaining feedback from 20 yoga therapy experts. The safety and efficacy of the two programs were subsequently tested in a prospective, multicenter, open-label single-arm study. Eighty-six adults (18 male, 68 female) were recruited from two tertiary mental healthcare institutions, 48 in NIMHANS, Bengaluru; and 38 in SCARF, Chennai. Participants were assessed at weeks zero, 4, and 16 using validated tools. Data were analyzed using a Mixed Model, Intention to Treat approach. After week 16, 31 subjects remained in the trial and continued to practice yoga without any side effects. Subjects who adhered in the trial had significantly higher levels of baseline anxiety and depression as compared to subjects who dropped out. Results at week 4 included significant reductions in levels of perceived stress, anxiety, and insomnia; improvements were maintained at week 16. Correlations between number of yoga sessions and post-intervention PSS scores were negative (r = −0.49), and significant (p< 0.05). Both tele-yoga programs proved safe, useful tools to counteract perceived stress, anxiety and insomnia. Future trials should explore the utility of tele-yoga as a tool to enhance well-being and manage stress.

Combined drought and salinity trigger unique lncRNA regulatory signatures in sweet sorghum (Sorghum bicolor L. Moench) compared to individual stress responses

Combined drought and salinity trigger unique lncRNA regulatory signatures in sweet sorghum (Sorghum bicolor L. Moench) compared to individual stress responses

When the Caregivers Need Care: The Silent Stress of Human Resources Work

The aim of this study is to examine the stress and pressure experienced by individuals working in human resources, focusing on the unique challenges that this work entails. This research is therefore guided by the question: what are the characteristics of work-related stress and burnout for individuals working in human resources? This study employed a mixed-methods approach, incorporating both qualitative and quantitative research methods. Initially, semi-structured interviews were conducted with eight human resources professionals, comprising an equal number of women and men. Subsequently, a survey was administered to a broader group of human resources personnel. The quantitative analysis utilized the “Copenhagen Burnout Inventory” as a measurement tool, alongside background questions regarding the participants’ gender, age, job title, field of work, and seniority. The findings from both the qualitative and quantitative research indicate that employees in human resource roles exhibit significant stress symptoms. A majority of the interviewees reported experiencing mental and/or physical symptoms attributable to work-related stress. Specifically, the quantitative data revealed that 65.7% of the participants sometimes or often feel mentally exhausted, while 40.3% report similar levels of physical exhaustion. Notably, despite these challenges, only 8.7% of the participants identify as being burnt-out in their roles. The quantitative results also highlight gender as a significant factor affecting the mental and physical well-being of human resources employees, with women reporting lower levels of well-being compared to men.

The Influence of the Ratio of Circumference to Cross-Sectional Area of Tensile Bars on the Fatigue Life of Additive Manufactured AISI 316L Steel

The static and dynamic loading capacities of components depend on the stress level to which the material is exposed. The fatigue behavior of materials manufactured using additive technology is accompanied by a pronounced scatter between the number of cycles at the same stress level, which is significantly greater than the scatter from a material with the same chemical composition, e.g., AISI 316L, but produced by rolling or forging. An important reason lies in the fact that fatigue cracks are initiated almost always below the material surface of the loaded specimen. Thus, in the article, assuming that a crack will always initiate below the surface, we analyzed the fatigue behavior of specimens with the same bearing cross section but with a different number of bearing rods. With a larger number of rods, the circumference around the supporting part of the rods was 1.73 times larger. Thus, experimental fatigue of specimens with different sizes showed that the dynamic loading capacity of components with a smaller number of bars is significantly greater and can be monitored by individual stress levels. Although there are no significant differences in loading capacity under static and low-cycle loading of materials manufactured with additive technologies, in high-cycle fatigue it has been shown that the ratio between the circumference and the loading cross section of tensile-loaded rods plays an important role in the lifetime. This finding is important for setting a strategy for manufacturing components with additive technologies. It shows that a better dynamic loading capacity can be obtained with a larger loading cross section.

12224 International Survey on Impacts of Pain & Feelings of Infertility on Depression, Anxiety and Stress in Individuals with Endometriosis

12224 International Survey on Impacts of Pain & Feelings of Infertility on Depression, Anxiety and Stress in Individuals with Endometriosis

Boosting Stevia's sweetness: Growth regulators mitigate salt stress and enhance steviol glycosides

Stevia rebaudiana Bertoni is a plant species with sweet-tasting leaves that can be used as a natural, low-calorie sweetener with potential health benefits. Salt stress can reduce plant growth and productivity, but the application of growth regulators like salicylic acid (SA), methyl jasmonate (MeJ), and spermidine (Spd) can manage various plant abiotic stresses and improve plant growth and productivity. In this work, we investigated the role of exogenous SA, MeJ, and Spd in conferring salt stress tolerance in Stevia by analyzing plant growth, chlorophyll (Chl), total phenolic, total carotenoid content, antioxidant defense system and steviol glycosides. The aim of a recent study was to assess the effects of these regulators on Stevia plants under both individual and combined salt stress conditions. Foliar application of these regulators improved plant growth under salt stress, with moderate salinity stress increasing glycoside compounds. SA was most effective in increasing rebaudioside A (Reb A), while MeJ + Spd combination was best for increasing stevioside (Stv) content. Individual applications of Spd, MeJ, and SA significantly impacted plant growth and antioxidant content, although their combined use was less effective. Spd application under salt stress yielded the highest increases in total carotenoid and Chl a content, while MeJ and Spd together significantly boosted Chl b content. The study found that SA enhanced superoxide dismutase (SOD) activity and reduced catalase (CAT) activity under salt stress, whereas MeJ alone increased both CAT and SOD activity. The distinct responses to Spd, SA, and MeJ suggest varied mechanisms in oxidative stress-induced antioxidant production. Overall, the use of these growth regulators can improve the growth, yield, and nutritional value of Stevia under salt stress, offering significant implications for agriculture and food security.

Effect of Psychological Resilience on Posttraumatic Growth Among Midwives: The Mediating Roles of Perceived Stress and Positive Coping Strategies.

To explore the relationship between midwives' psychological resilience and posttraumatic growth, and the mediating role of perceived stress and positive coping strategies. A multicentre cross-sectional survey was used. Data were conducted among 339 midwives from 24 Grade III A hospitals in Sichuan Province from April to July 2023, using the Chinese version of the Connor Davidson Resilience Scale, Chinese version Perceived Stress Scale, Simplified Coping Style Questionnaire, Chinese-Posttraumatic Growth Inventory and General Demographic Data Questionnaire. A descriptive statistical approach, Pearson's correlation analysis and the Mplus 8.3 were used to analyse the available data. There was a significant correlation between psychological resilience, perceived stress, positive coping strategies and PTG. Psychological resilience could have a direct positive impact on PTG of midwives, but it could also indirectly affect PTG of midwives through three pathways: the mediating effect of perceived stress, the mediating effect of positive coping strategies and the chain mediating effect of perceived stress and positive coping strategies. Results suggest that nursing managers should help to improve the psychological resilience of midwives and to reduce individual stress perception, enhance coping abilities and achieve positive growth. Prior to data collection, we obtained approval from the nursing department of each hospital. Midwives who met the inclusion and exclusion criteria gave informed consent and invited to participate in this study. This study was guided by STROBE. During the data collection phase, 349 midwives took the time to carefully answer the questionnaire items related to this study.

Stress in the social environment: behavioural and social consequences of stress transmission in bird flocks.

The stress response helps individuals cope with challenges, yet how individual stress levels shape group-level processes and the behaviour of other group members has rarely been explored. In social groups, stress responses can be buffered by others or transmitted to members that have not even experienced the stressor first-hand. Stress transmission, in particular, can have profound consequences for the dynamics of social groups and the fitness of individuals therein. We experimentally induced chronic stress within replicated colonies of zebra finches and used fine-scale tracking to observe the consequences of stress-exposed colony members for the behaviour and reproduction of non-manipulated colony members. Non-manipulated individuals in colonies containing stress-exposed individuals exhibited reduced activity, and fewer-but more differentiated-social bonds. These effects were stronger in colonies with a greater proportion of stress-treated individuals, demonstrating that the impact of stressors can reach beyond directly exposed individuals by also affecting their group mates. We found no evidence that socially transmitted stress affected reproduction or long-term physiological measurement in unmanipulated birds, even though the stress-exposed demonstrators laid slightly fewer eggs and showed stressor-dependent changes in feather corticosterone. Social transmission of these effects, if occurring at all, might be more subtle.

Transactional experiences of discrimination, depressive symptoms, and ethnoracial socialization in Mexican-origin families.

Racial-ethnic discrimination is a prevalent stressor for Mexican-origin individuals that potentiates health inequities in depressive symptoms. However, existing research has primarily focused on individual-level associations between discrimination and depressive symptoms, neglecting the interdependent nature within family systems. Little is known about how one family member's discriminatory experiences relate to the depressive symptoms of others. Although ethnoracial socialization may disrupt the link from discrimination to depressive symptoms, how different ethnoracial socialization practices operate and influence parents themselves have not been examined. This study examines the associations among discriminatory experiences, depressive symptoms, and ethnoracial socialization among 604 Mexican-origin adolescents and their parents from low-income families. The findings revealed intraindividual and interindividual discrimination-depressive symptoms associations. Parental ethnoracial socialization's role in the link varied over time, individuals, and practices. Mental health research and services should consider shared and nonshared experiences among family members and adopt personalized approaches to support different family members. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

BDNF methylation associated with stress in women: Novel insights in epigenetics and inflammation

The brain-derived neurotrophic factor (BDNF) gene plays an important role in modulating the stress-response axis and inflammation, which can be regulated by epigenetic mechanisms. BNDF methylation has been associated with stress-related psychiatric disorders such as depression, anxiety and post-traumatic stress. Previous studies have reported that stressful events are involved with long-lasting alterations in DNA methylation (DNAm) of the BNDF exon IV promoter, suggesting that glucocorticoids and inflammatory cytokines can regulate this process. We previously found that perceived psychological stress is modulated by inflammatory cytokines, such as interleukin (IL)-6, IL-8 and IL-10, and IL-12p70, suggesting their role in mediating the stress response. However, the epigenetic mechanism mediating this response has yet to be fully understood. In this study, we propose that high perceived stress and high serum levels of inflammatory cytokines may correlate with specific methylation sites within the BNDF exon IV promoter. To address these questions, we conducted a cross-sectional study of 82 adult women teachers working in basic education in Brazil. The perceived stress scale was used to assess stress and blood samples were collected for the measurement of inflammatory markers and BNDF methylation through flow cytometry assay and DNA pyrosequencing, respectively. We detected differentially methylated CpG sites in the BNDF gene, where 5 CpG sites were directly correlated with high stress levels. However, 4 CpG sites showed inverse effects, indicating that changes in methylation levels in those sites could lead to a protective effect on perceived stress. About inflammatory markers, IL-6 and IL-8 were associated with high perceived stress. However, only IL-8 and IL-10 showed simultaneous modulation of perceived stress, while IL-10 and IL12p70 correlated with DNAm. We found that higher levels in IL-10 and IL-12p70 serum decrease methylation in CpG11. A direct relationship was also found to IL-12p70, where higher levels in serum increase methylation in CpG5 and 13, respectively. Taken as a whole, our findings reinforce the hypothesis regarding stress-sensitive regions within the BDNF gene, mainly for CpG5, 11, and 13. In addition to these results, CpG7 and 9 may be regarded as stress-protective regions. Our data suggest that BDNF DNAm in the blood may represent a novel biomarker for early detection of adverse effects of chronic exposure to stress in healthy individuals.

Deciphering Acclimation to Sublethal Combined and Sequential Abiotic Stresses in Arabidopsis thaliana.

Plants are frequently exposed to environmental challenges. Responses to sub-lethal abiotic stress combinations are complex and often distinct from responses to individual stresses and remain poorly understood. Investigating traits and molecular factors mediating acclimation to stress combinations is essential for the development of climate change-resilient field crops. Here, we studied the morphological, physiological, and molecular responses of Arabidopsis thaliana to i) co-occurring high temperature and drought and ii) flooding followed by drought, both of which have increased in frequency due to climate change, and the individual component stresses: high temperature, drought and flooding. A set of 15 physiological and morphological traits were assessed during single and combined stresses. By combining these comprehensive trait analyses with transcriptome characterization, we established the generally additive negative effects of simultaneous or sequential stresses on plant morphology and physiology compared to the corresponding individual stresses. Although drought had a mild effect on various growth, morphological and physiological traits in both stress combinations, a unique transcriptome signature emerged upon combination with high temperature simultaneously or flooding sequentially. Molecular processes identified as important for multi-stress resilience included plastid-nucleus communication, ABA signaling and photo-acclimation. Based on the RNA-seq data, a set of 39 genes was identified as potential multi-stress response regulators. Mutants were tested to validate the contribution of these genes to plant survival and phenotypic acclimation under combined stress. We confirmed the involvement of several genes in regulating phenotypic acclimation traits. Among the identified factors were EARLY FLOWERING 6 (ELF6) and ARABIDOPSIS TÓXICOS EN LEVADURA 80 (ATL80), with substantial effects on plant growth, leaf development and plant survival (wilting) during high-temperature drought and post-submergence drought, respectively.

Transfer from goal-directed behavior to stimulus-response habits and its modulation by acute stress in individuals with risky gaming behavior

Habitual responses towards addiction-related cues play a relevant role in the development and maintenance of addictions. Such automatic responses may be more likely under stress, as stress has been shown to induce a shift from goal-directed to habitual behavior. The current study investigated these mechanisms in risky gaming behavior. Individuals with risky gaming behavior (n = 68), as established by a structured clinical interview, and a matched control group (n = 67) completed a Pavlovian-to-Instrumental Transfer (PIT) paradigm with gaming-related cues and rewards. After the Pavlovian training, participants underwent a stress (Trier Social Stress Test) or control condition before performing the instrumental training and the transfer phase of the PIT paradigm. To assess habitual behavior, the gaming-related rewards were devalued after half of the transfer phase. In both groups, gaming-related cues enhanced the choice of the gaming-related reward and this gaming PIT effect was reduced, however, not eliminated by the devaluation. Unexpectedly, stress did not significantly increase responding for the gaming-related reward in participants aware of the stimulus-outcome associations, however seemed to enhance habitual responding in unaware participants. Our findings underline the relevance of gaming-related cues in triggering habitual responses, which may undermine attempts to change a problematic gaming behavior.

Stress Resilience And Resilience Factors Across 9 European Samples During The COVID-19 Pandemic

Abstract While many describe changes in mental health over the pandemic, we investigate change in resilience over time during the pandemic. Stress resilience can be operationalised as stressor reactivity, that is, how much a person’s mental health is affected by the stressors that they experience. Utilising the individual participant data (IPD) meta-analyses megadataset available we first define and quantify how many stressors individuals. We then regress this stressor exposure on mental health within each sample to compute each sample’s normative stressor reactivity. Each person’s individual stressor reactivity is then calculated as the residual to this line at each time points. Resilient outcomes can be understood as lower reactivity as this indicates lower susceptibility to stressors. Stressor reactivity (SR) scores control for individual stressor exposure, therefore allowing us to investigate resilience factors during a time in which exposure to macro and micro stressors varied greatly between individuals. Further, SR scores are a harmonised outcome that can easily compared across different samples in the IPD dataset. Using this outcome, we present findings on resilience trajectories and identify factors that are associated with resilient outcomes. We also disentangle the role of current stressor exposure and prior stressors, showing that prior exposure to stressors increases vulnerability in subsequent exposures. Our findings show that stressor reactivity over time was more stable than mental health symptoms during the pandemic, therefore indicating that SR as an outcome offers new insights into the impact of the pandemic.

Improving RCCE-IM for LGBTQ+ migrants: Lessons learned from COVID-19 Pandemic

Abstract Background To foster equity during a pandemic event, public health practitioners must be mindful of social and political circumstances that inform poor health. This is especially true for populations who are exposed to several factors that structure health inequity, such as lesbian, gay, bisexual, transgender, or otherwise queer identifying (LGBTQ+) populations. We aim to report on the specific challenges of LGBTQ+ people, including those who belong to the migrant communities, during the COVID-19 pandemic and find out their needs in risk communication (RC), community engagement (CE) and infodemic management (IM). Methods We will first review findings of studies conducted in Portugal, UK, Italy, Brazil, Chile, and Sweden, between 2020-2023, in the context of “Project Global Queerantine”, then report on the additional challenges that LGBTQ+ people faced when living in migrant communities. Results LGBTQ+ individuals perceived their psychological wellbeing to have been greatly affected by the pandemic. Stressors included fear of the disease itself, and fear of spreading the virus, as well as the negative consequences of adhering to the recommendations of social distancing, which constantly interplayed with the marginalized position of being a LGBTQ+ person. Limited access to the LGBTQ+ community was a common stressor for trans individuals who faced prolonged waiting times for “gender dysphoria” assessment and hormone treatment. The intersectionality of vulnerability mechanisms experienced by LGBTQ+ migrants exacerbated all these issues, as did challenges in accessing and comprehending COVID-19-related information. Conclusions During health crises, it is critical for RCCE-IM efforts to consider the increased mental health issues and disruption of social support networks that LGBTQ+ people may face. Strategies and examples of good practices for RCCE-IM that are specifically tailored to LGBTQ+ migrants will be developed in collaboration with the workshop participants.