Microanalyzed global parent interview variables that had previously differentiated stress-resilient (SR) and stress-affected (SA) outcomes in independent samples (4th–6th and 2nd–3rd grade) of multiethnic, highly stressed, urban children. The in-depth interview assessed caregiving environment and early child development. On item-level t tests for the pooled sample, 36 of 144 items differentiated the groups. Discriminant function analysis identified a cluster of nine sensitive items that correctly classified 81.7% of children as SR or SA. Factor analysis of the 36 items identified a 4-factor solution: Child Adjustment, Early Temperament, Parent-Child Relationship, and Developmental Milestones; SR parents exceeded SAs on each. Structurally comparable analyses using only Sample 2 and including the second interview's new measures, replicated and extended findings from the pooled sample. Overall, study findings enhance understanding of resilience and testify to the merit of using a microanalytic approach in this research area. Implications for streamlining existing measures and for future research directions are considered. © 2001 John Wiley & Sons, Inc.