The purpose of this study is to demonstrate the clinical use of the point spread function (PSF) as metric for the assessment of retinal image quality in eyes with different ocular conditions. The PSF was computed from the wavefront aberrations obtained in seven eyes with different ocular conditions: emmetropia, myopia, hyperopia, post-myopic laser in situ keratomileusis (LASIK), post-hyperopic LASIK, keratoconus, Intacs® in keratoconus, radial keratotomy (RK), LASIK after RK, cataract, phacoemulsification after cataract surgery, and LASIK after astigmatic keratotomy. The Strehl intensity ratio was calculated for all the PSFs computed. The PSF was correlated with the change in the optical elements of the eye: cornea and lens. Corneal refractive surgery, keratoconus, Intacs insertion and cataract surgery induce different changes in the optics of the eye which were well reflected by the PSF and the Strehl intensity ratio. Spread of the PSF in each case was caused by optical aberrations and/or scatter. The PSF measurement and the Strehl intensity ratio calculation is useful for the qualitative assessment of the retinal image and for quantifying optical degradation imposed by different optical conditions.
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