ABSTRACT This paper explores the governance and resilience of the urban street economy in Ghanaian cities as a reflection of the operational features of informality in African cities. The paper draws on a comprehensive review of secondary documents to explore the practices, policy regulation, urban governance challenges, and resilience of the street economy in urban Ghana. Findings show that eviction, relocation, harassment, and merchandise confiscation are the orthodox policy measures by city authorities for managing and regulating street vending. Nevertheless, the street economy continuously reproduces and spatially redistributes itself across the urban landscape, exemplifying its resilience despite state intolerance and repression. The paper concludes by recommending that city authorities embrace street vending, and by extension, urban informality, as a part of Southern urbanism and, therefore, develop more inclusive and less hostile policies to regulate such activities.