Event Abstract Back to Event Parallel acquisition of allocentric and egocentric navigation strategies in the human brain Kinga Igloi1*, Christian Doeller2, Alain Berthoz1, Neil Burgess2 and Laure Rondi-Reig3 1 LPPA College de France, France 2 ICN UCL, France 3 CNRS, NPA UPMC, France Navigation in a complex environment can rely on the use of different spatial strategies. We focused on allocentric (or encoding interrelationships among environmental cues, movements, and the location of the goal) and sequential egocentric (or sequences of body turns associated with specific choice points) strategies. Traditional questions on learning speed and hierarchy between strategies are still debated. Here we adapted a novel spatial paradigm, developed for rodents, first in a behavioral study then for use with fMRI in humans and asked the question if allocentric and egocentric strategies are acquired in parallel. We first investigated spontaneous or imposed choice and switches between these two spatial strategies in a behavioral study: our results show bi-directional strategy switches, suggesting no temporal or performance-related hierarchy between strategies. Second, using fMRI, we showed that allocentric navigation activates a neural network comprising the right hippocampus, ventral and dorsal striatum and the precuneus; whereas sequential egocentric navigation involves the left hippocampus, ventral and dorsal striatum and the posterior insula. We further report parallel activation of the main neural structures identified in both strategies (bilateral hippocampus, precuneus, striatum, insula) during the initial learning process, thus confirming parallel acquisition of these two strategies. Additionally, medial prefrontal activation could be linked to cognitive control and monitoring of available strategies during learning. Interestingly, both strategies can be identified in hippocampal activity prior to their expression in behavior. We show that, activation of the right hippocampus supports the allocentric strategy (memory for places), while activation of the left hippocampus supports the sequential egocentric strategy (memory for temporal sequences), which can be used to support both spatial navigation and episodic memory more generally. Conference: 41st European Brain and Behaviour Society Meeting, Rhodes Island, Greece, 13 Sep - 18 Sep, 2009. Presentation Type: Poster Presentation Topic: Poster presentations Citation: Igloi K, Doeller C, Berthoz A, Burgess N and Rondi-Reig L (2009). Parallel acquisition of allocentric and egocentric navigation strategies in the human brain. Conference Abstract: 41st European Brain and Behaviour Society Meeting. doi: 10.3389/conf.neuro.08.2009.09.177 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 10 Jun 2009; Published Online: 10 Jun 2009. * Correspondence: Kinga Igloi, LPPA College de France, Paris, France, kinga.igloi@college-de-france.fr Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Kinga Igloi Christian Doeller Alain Berthoz Neil Burgess Laure Rondi-Reig Google Kinga Igloi Christian Doeller Alain Berthoz Neil Burgess Laure Rondi-Reig Google Scholar Kinga Igloi Christian Doeller Alain Berthoz Neil Burgess Laure Rondi-Reig PubMed Kinga Igloi Christian Doeller Alain Berthoz Neil Burgess Laure Rondi-Reig Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.
Read full abstract