Strategic Retrieval Research Articles

People sometimes remember to forget: Strategic retrieval from the list before last enables directed forgetting of the most recent information.

List-method directed forgetting usually involves asking people to study a list, followed by a cue to forget it, and then studying a second list. Prior work suggests that List 2 encoding is necessary for directed forgetting to occur, but recent studies have found that moving the forget cue from List 1 to List 2 allows people to selectively forget List 2. These results were attributed to an inhibitory mechanism. In four experiments, we aimed to replicate these findings and provide an alternative explanation based on the list-before-the-last paradigm. We propose that in the forget condition, participants may strategically retrieve List 1 in response to the forget cue, contributing to selective forgetting. Previous research suggests that explicit retrieval of earlier-leaned information causes a contextual shift, resulting in forgetting of target information. Verbal reports from Experiments 1 and 2 indicated that participants often covertly select a retrieval strategy to forget the most recent list. In Experiment 3, explicit instructions to retrieve resulted in significant forgetting. Directly manipulating forgetting strategy between participants in Experiment 4 suggested that retrieval may be one of several effective mechanisms to forget recently-encountered information. In the retrieval conditions, the data support our claim that in the absence of explicit postcue encoding, people can strategically retrieve earlier-learned information to forget. This novel forgetting mechanism is probably also used outside of the laboratory to "roll back" memory for incorrect information. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

To ask or not to ask: strategic recall, but not spontaneous recall, decreases by the passage of time in 46-month-olds' memory of a unique event.

Children's ability to intentionally recall events lessens with temporal distance to the occurrence. However, little is known about the effects of retention time on memories that emerge spontaneously. We examined spontaneous and strategic retrieval in eighty-one 46-month-olds' memory of a lab event after 1 week (the 1-week Condition) versus 43weeks (the 43-weekCondition) in a between-subjects design, using well-established procedures (Krøjgaard et al., in Consciousness and Cognition 55(91): 105, 2017). While spontaneous recall showed no significant effect of retention, the children's strategic recall was negatively affected: even though the children overall still remembered the event, the children in the 43-week Condition showed reduced voluntary recall compared to the children in the 1-week Condition. To our knowledge, this is the first study to assess spontaneous recall after such a long retention interval. The findings add to existing evidence of two modes of retrieval in early childhood and are of both theoretical and forensic relevance.

Supplemental Material for People Sometimes Remember to Forget: Strategic Retrieval From the List Before Last Enables Directed Forgetting of the Most Recent Information

Supplemental Material for People Sometimes Remember to Forget: Strategic Retrieval From the List Before Last Enables Directed Forgetting of the Most Recent Information

The role of attention and ageing in the retrieval dynamics of value-directed remembering.

For memory to be efficient, people need to remember important information. This involves selective encoding and retrieval operations to maximise the recall of valuable information at the expense of less important information. While past research has examined this in terms of strategic encoding operations, we investigated differences in the dynamics of retrieval in value-directed remembering tasks with younger adults under full and divided attention during encoding as well as in older adults. Participants typically initiated recall with the first presented, last presented, or highest valued words and also strategically organised retrieval according to information value such that high-value words tended to be recalled before low-value words. However, the average value of older adults' first recalled word was greater than that of younger adults, likely contributing to their enhanced selectivity. In addition, there were no differences in lag-conditional-response probabilities in younger adults under full or divided attention, but older adults showed impairments in the retrieval of items sharing contextual features with nearby items, while younger adults relied more on temporal-contextual cues to recall words. Together, this study suggests that both strategic encoding and strategic retrieval operations contribute to selectivity for valuable information and older adults may be able to maximise retrieval operations despite displaying impairments in temporal binding during encoding and an overall recall deficit.

In silico strategic curation, retrieval and prediction of novel antimicrobial peptide from Locusta migratoria transcriptome

Abstract Evolutionary immune system upgradation is done by all living organism to survive from the invading pathogens. Insects has a strong defense system comprising of anatomical barrier, humoral antimicrobial peptide (AMP) production and cellular immune components. Locusta migratoria (L. migratoria) is an agricultural pest insect migrating long distance might encounter distinct pathogens. Owing to this, we aimed in identifying AMPs present in the L. migratoria and elucidate the antimicrobial activity. The migratory locust was immunized with Escherichia coli, Staphylococcus aureus, Candida albicans mixture, then RNA was isolated and sequenced. The L. migratoria transcriptome was de novo assembled using trinity and screened for AMPs propensity specifically molecular and aggregation properties. The novelty is tested by blasting in known AMP databases. Finally, obtained novel putative AMPs were then tested for antimicrobial and hemolytic activity. The prediction resulted in 3,524 putative AMPs which was further screened down to ten AMPs for final testing. Two peptides showing promising antimicrobial effects were obtained. All the analyzed peptides showed no hemolysis confirms its non-toxicity. Thus, our peptides could be promising drug candidate and can be used as an alternative to antibacterial or antifungal therapy with further validations.

Executive function and high ambiguity perceptual discrimination contribute to individual differences in mnemonic discrimination in older adults

Mnemonic discrimination deficits, or impaired ability to discriminate between similar events in memory, is a hallmark of cognitive aging, characterised by a stark age-related increase in false recognition. While individual differences in mnemonic discrimination have gained attention due to potential relevance for early detection of Alzheimer's disease, our understanding of the component processes that contribute to variability in task performance across older adults remains limited. The present investigation explores the roles of representational quality, indexed by perceptual discrimination of objects and scenes with overlapping features, and strategic retrieval ability, indexed by standardised tests of executive function, to mnemonic discrimination in a large cohort of older adults (N=124). We took an individual differences approach and characterised the contributions of these factors to performance under Forced Choice (FC) and Yes/No (YN) recognition memory formats, which place different demands on strategic retrieval. Performance in both test formats declined with age. Accounting for age, individual differences in FC memory performance were best explained by perceptual discrimination score, whereas YN memory performance was best explained by executive functions. A linear mixed model and dominance analyses confirmed the relatively greater importance of perceptual discrimination over executive functioning for FC performance, while the opposite was true for YN. These findings highlight parallels between perceptual and mnemonic discrimination in aging, the importance of considering demands on executive functions in the context of mnemonic discrimination, and the relevance of test format for modulating the impact of these factors on performance in older adults.

Unraveling the role of retrieval deficits in autobiographical memory impairment in schizophrenia: A comparison of involuntary and voluntary autobiographical memories

Patients with schizophrenia show severe autobiographical memory impairment, thought to reflect retrieval deficits caused by executive dysfunction. However, prior research has focused exclusively on strategic (voluntary) retrieval, and ignored involuntary retrieval resulting from automatic and associative processes, involving minimal cognitive control. We report two studies with patients diagnosed with schizophrenia (Ns = 40 and 50 respectively) comparing their impairment in involuntary versus voluntary autobiographical memory. We use two different methodologies, not previously used in schizophrenia research: a naturalistic study involving real-life data and an experimental setup. Both studies consistently showed that involuntary and voluntary autobiographical memories were similarly impaired in schizophrenia. The absence of interaction effects between group and retrieval suggests that schizophrenic patients did not benefit from memory tasks involving little retrieval effort. These findings suggest that autobiographical memory impairment in schizophrenia are not caused by problems with self-initiated voluntary retrieval, but instead likely reflect encoding or binding deficits.

Involuntary autobiographical memories and their relation to other forms of spontaneous thoughts.

Involuntary autobiographical memories are memories of personal events that come to mind spontaneously-that is, with no conscious initiation of the retrieval process. Such spontaneously arising memories were long ignored in cognitive psychology, which generally has focused on controlled and strategic forms of remembering, studied in laboratory settings. Recent evidence shows that involuntary memories of past events are highly frequent in daily life, and that they represent a context-sensitive, and associative way of recollecting past events that involves little executive control. They operate by constraints that favour recent events and events with a distinct feature overlap to the current situation, which optimizes the probability of functional relevance to the ongoing situation. In addition to adults, they are documented in young children and great apes and may be an ontogenetic and evolutionary forerunner of strategic retrieval of past events. Findings suggest that intrusive involuntary memories observed clinically after traumatic events should be viewed as a dysfunctional subclass of otherwise functional involuntary autobiographical memories. Because of their highly constrained, situation-dependent and automatic nature, involuntary autobiographical memories form a distinct category of spontaneous thought that cannot be equated with mind wandering. This article is part of the theme issue 'Offline perception: voluntary and spontaneous perceptual experiences without matching external stimulation'.

Recall and Recognition in Alzheimer's Disease and Frontotemporal Dementia.

It has long been debated whether performance on recall and recognition tests depends on the same or different memory systems and whether performance on these two tasks is dissociated in clinical populations. According to Dual process theories of recall, performance on recall and recognition tests dissociates in the relative reliance on frontal lobe related activities; in fact, the recall test requires more strategic retrieval of memoranda than the recognition task. By contrast, Dual process theories of recognition posit that performance on these tests differs in the relative contribution of recollection and familiarity memory processes in the two tasks: both recollection and familiarity contribute to recognition judgments, but only recollection supports recall performance. The aim of this study was to clarify the cognitive processes involved in recall and recognition in patients with dementia. We administered a 15-word recall task followed by a yes/no recognition paradigm to 28 patients with Alzheimer's disease (AD), 22 patients with the behavioral variant of frontotemporal dementia (bvFTD), and 45 normal controls (NCs). Results showed that on the delayed recall task, bvFTD patients performed much better than AD patients but the two groups did not differ on any index of recognition performance. The present data support the hypothesis that the performance of the two groups is expression of the different reliance on recollection (more impaired in the AD than in the bvFTD group) and familiarity (similarly impaired in the two groups) in performance on recall and recognition tasks.

The effects of aging and an episodic specificity induction on spontaneous task-unrelated thought.

When voluntarily describing their past or future, older adults typically show a reduction in episodic specificity (e.g., including fewer details reflecting a specific event, time and/or place). However, aging has less impact on other types of tasks that place minimal demands on strategic retrieval such as spontaneous thoughts. In the current study, we investigated age-related differences in the episodic specificity of spontaneous thoughts using experimenter-based coding of thought descriptions. Additionally, we tested whether an episodic specificity induction, which increases episodic detail during deliberate retrieval of events in young and older adults, has the same effect under spontaneous retrieval. Twenty-four younger and 24 healthy older adults performed two counterbalanced sessions including a video, the episodic specificity or control induction, and a vigilance task. In the episodic specificity induction, participants recalled the details of the video while in the control they solved math exercises. The impact of this manipulation on the episodic specificity of spontaneous thoughts was assessed in the subsequent vigilance task, in which participants were randomly stopped to describe their thoughts and classify them as deliberate/spontaneous. We found no differences in episodic specificity between age groups in spontaneous thoughts, supporting the prediction that automatic retrieval attenuates the episodic specificity decrease in aging. The lack of age differences was present regardless of the induction, showing no interactions. For the induction, we also found no main effect, indicating that automatic retrieval bypasses event construction and accesses pre-stored events. Overall, our evidence suggests that spontaneous retrieval is a promising strategy to support episodic specificity in aging.

Age Affects Strategic But Not Spontaneous Recall in 35- and 46-Month-old Children

ABSTRACT It is well documented that young children have difficulties with strategically remembering past events. Recent evidence on event memory in 35- and 46-month-old children suggests that strategic retrieval (yes/no questions) improves with age, whereas spontaneous retrieval is relatively unaffected by age. We here replicate and extend those findings (N = 124): First, a novel free (strategic) recall test was added to improve ecological validity. Second, the free recall procedure allowed us to make direct comparisons between spontaneous and free strategic recall relative to age. The free recall test revealed similar results in the standard yes/no questions (older children outperformed younger). The direct comparison between spontaneous and free recall revealed a reliable interaction between age and retrieval mode: While the children’s age did not affect spontaneous recall, the 46-month-olds outperformed the 35-month-olds on the free recall test. The results add to the accumulating evidence that spontaneous recall of events is an early developmental achievement.

Intact strategic retrieval processes in older adults: no evidence for age-related deficits in source-constrained retrieval

ABSTRACTAging is thought to involve impairments to cognitive control functions that support episodic memory, for example by enabling people to strategically constrain their retrieval search towards a specific context (“source”) in order to facilitate retrieval of goal-relevant memories. The “memory-for-foils” paradigm investigates source-constrained retrieval by assessing whether incidental encoding of new foils during an old/new recognition test differs depending on the type of processing that was previously used during study of the old items in the test. If it does, it suggests that people process foils differently as a result of engaging in source-constrained retrieval attempts. Young adults typically show differences in incidental encoding foils, but such differences have not been found in older adults. Here, we compared source-constrained retrieval and reward effects on incidental foil encoding between younger and older adults, to assess if age-related reductions in strategic retrieval processing are accompanied by differences in responsiveness to external rewards. The results showed only minor effects of rewards on memory processing, in younger adults only. Contrary to prior findings, older adults had equivalent overall memory performance and spontaneously constrained retrieval to the same extent as the young group, showing that aging-related impairments to strategic retrieval processes are not inevitable.

Proofreading by students: implications of executive and non-executive components of working memory in the detection of phonological, orthographical, and grammatical errors

The present research studied the role of the nonexecutive and executive components of working memory in the detection of typographical, lexical, and grammatical errors. Before performing the error detection tasks, undergraduate participants completed a battery of tasks that evaluated nonexecutive functions (verbal and visuospatial storage) and executive functions (coordination of verbal and visuospatial storage and processing, strategic retrieval from long-term memory, effortful shifting) as support working memory. The analyses found that typographical errors were better detected than grammatical errors, followed by lexical errors. Visuospatial storage and coordination of verbal storage and processing were significant predictors of detection of typographical and lexical errors. Effortful shifting was a significant predictor only of detection of lexical errors, while strategic retrieval in long-term memory was the only predictor of detection of grammatical errors. Globally, in the verbal domain, the executive component of working memory appeared more involved than the nonexecutive component whereas, in the visuospatial domain, the nonexecutive component seems more involved than the executive component.

The effects of sleep on prospective memory: a systematic review and meta-analysis

Summary Prospective memory (PM) enables us to execute previously conceived intentions at a later time and is used when remembering to call a friend or submitting a proposal on time. Evidence that sleep benefits PM is presently mixed. Further, when a benefit is observed, it is unclear if this is achieved through improvements in strategic monitoring (maintaining an intention in mind and searching for cues) or spontaneous retrieval (an automatic process occurring without preparatory attention). We conducted a meta-analysis of 24 independent samples (N = 165,432) to quantify the effect of sleep on PM and gain clarity regarding the retrieval process benefitted by sleep. Cohen's d with 95% confidence intervals (CI95) were derived using random-effects models. The benefit of sleep on PM was statistically significant and in the small to medium range (d = 0.41, CI95 = 0.25–0.56). Moreover, sleep did not appear to influence monitoring (d = −0.11, CI95 = −0.40–0.17). In contrast, the benefits of sleep are significantly greater when the likelihood of spontaneous retrieval is high (d = 0.94, CI95 = 0.44–1.44) versus low (d = 0.45, CI95 = −0.02–0.93), suggesting that sleep may leverage on spontaneous retrieval processes to improve PM. These findings inform theoretical models of sleep and PM that could sharpen strategies to improve memory function in vulnerable populations.

Cognitive control depletion reduces pre-stimulus and recollection-related measures of strategic retrieval.

Background: The ability to strategically retrieve task-relevant information from episodic memory is thought to rely on goal-directed executive processes, and there is evidence that neural correlates of strategic retrieval are sensitive to reserves of cognitive control. The present study extended this work, exploring the role of cognitive control in the flexible orienting of strategic retrieval processes across alternating retrieval goals. Method: Pre-stimulus cues directed participants to endorse memory targets from one of two encoding contexts, with the target encoding context alternating every two trials. Items from the nontarget encoding context were rejected alongside new items. One group of participants completed a Stroop task prior to the memory test in order to deplete their reserves of cognitive control, while a second group performed a control task. Event-related potentials (ERPs) were recorded throughout the memory task, and time-locked to both pre-stimulus cues and memory probes. Results: Control participants' pre-stimulus ERPs showed sustained divergences at frontal electrode sites according to retrieval goal. This effect was evident on the first trial of each memory task, and linked with the initiation of goal-specific retrieval orientations. Control participants also showed enhanced ERP correlates of recollection (the 'left parietal effect') for correctly classified targets relative to nontargets on the second trial of each memory task, indexing strategic retrieval of task-relevant information. Both the pre-stimulus index of retrieval orientation and the target/nontarget left parietal effect were significantly attenuated in participants that completed the Stroop task. Conclusions: The reduction of pre-stimulus and stimulus-locked ERP effects following the Stroop task indicates that available reserves of cognitive control play an important role in both proactive and recollection-related aspects of strategic retrieval.

Cognitive control depletion reduces pre-stimulus and recollection-related measures of strategic retrieval

Background: The ability to strategically retrieve task-relevant information from episodic memory is thought to rely on goal-directed executive processes, and there is evidence that neural correlates of strategic retrieval are sensitive to reserves of cognitive control. The present study extended this work, exploring the role of cognitive control in the flexible orienting of strategic retrieval processes across alternating retrieval goals. Method: Pre-stimulus cues directed participants to endorse memory targets from one of two encoding contexts, with the target encoding context alternating every two trials. Items from the nontarget encoding context were rejected alongside new items. One group of participants completed a Stroop task prior to the memory test in order to deplete their reserves of cognitive control, while a second group performed a control task. Event-related potentials (ERPs) were recorded throughout the memory task, and time-locked to both pre-stimulus cues and memory probes. Results: Control participants’ pre-stimulus ERPs showed sustained divergences at frontal electrode sites according to retrieval goal. This effect was evident on the first trial of each memory task, and linked with the initiation of goal-specific retrieval orientations. Control participants also showed enhanced ERP correlates of recollection (the ‘left parietal effect’) for correctly classified targets relative to nontargets on the second trial of each memory task, indexing strategic retrieval of task-relevant information. Both the pre-stimulus index of retrieval orientation and the target/nontarget left parietal effect were significantly attenuated in participants that completed the Stroop task. Conclusions: The reduction of pre-stimulus and stimulus-locked ERP effects following the Stroop task indicates that available reserves of cognitive control play an important role in both proactive and recollection-related aspects of strategic retrieval.

Cognitive control depletion reduces pre-stimulus and recollection-related measures of strategic retrieval.

Background: The ability to strategically retrieve task-relevant information from episodic memory is thought to rely on goal-directed executive processes, and there is evidence that neural correlates of strategic retrieval are sensitive to reserves of cognitive control. The present study extended this work, exploring the role of cognitive control in the flexible orienting of strategic retrieval processes across alternating retrieval goals. Method: Pre-stimulus cues directed participants to endorse memory targets from one of two encoding contexts, with the target encoding context alternating every two trials. Items from the nontarget encoding context were rejected alongside new items. One group of participants completed a Stroop task prior to the memory test in order to deplete their reserves of cognitive control, while a second group performed a control task. Event-related potentials (ERPs) were recorded throughout the memory task, and time-locked to both pre-stimulus cues and memory probes. Results: Control participants' pre-stimulus ERPs showed sustained divergences at frontal electrode sites according to retrieval goal. This effect was evident on the first trial of each memory task, and linked with the initiation of goal-specific retrieval orientations. Control participants also showed enhanced ERP correlates of recollection (the 'left parietal effect') for correctly classified targets relative to nontargets on the second trial of each memory task, indexing strategic retrieval of task-relevant information. Both the pre-stimulus index of retrieval orientation and the target/nontarget left parietal effect were significantly attenuated in participants that completed the Stroop task. Conclusions: The reduction of pre-stimulus and stimulus-locked ERP effects following the Stroop task indicates that available reserves of cognitive control play an important role in both proactive and recollection-related aspects of strategic retrieval.

Neural evidence for age-related differences in representational quality and strategic retrieval processes

Mounting behavioral evidence suggests that declines in both representational quality and controlled retrieval processes contribute to episodic memory decline with age. The present study sought neural evidence for age-related change in these factors by measuring neural differentiation during encoding of paired associates and changes in regional blood oxygenation level–dependent activity and functional connectivity during retrieval conditions that placed low (intact pairs) and high (recombined pairs) demands on controlled retrieval processes. Pattern similarity analysis revealed age-related declines in the differentiation of stimulus representations at encoding, manifesting as both reduced pattern similarity between closely related events and increased pattern similarity between distinct events. During retrieval, both groups increased recruitment of areas within the core recollection network when endorsing studied pairs, including the hippocampus and angular gyrus. In contrast, only younger adults increased recruitment of, and hippocampal connectivity with, lateral prefrontal regions during correct rejections of recombined pairs. These results provide evidence for age-related changes in representational quality and in the neural mechanisms supporting memory retrieval under conditions of high, but not low, control demand.

Verbal Fluency Development Across Childhood: Normative Data from Brazilian-Portuguese Speakers and Underlying Cognitive Processes.

Verbal fluency (VF) tasks are widely used to investigate children's lexical knowledge and executive functions skills. Consistency of measurement of the strategic retrieval components is still an issue and performance of Brazilian-Portuguese speaking children are currently not available. A cross-sectional study investigated the effects of age, school type (public × private) and the influence of language, memory and inhibitory control on VF. We assessed 414 Brazilian children, aged 6-12, in the number of words produced and both clustering and switching components, with two measures of VF: letter (LVF) and semantic (SVF). Analysis of the number of words produced showed a significant increase between 6-8-year-olds, 9-10-year-olds and 11-12-year-olds in SVF, while in LVF, the differences were significant only in the later age group. In SVF, the numbers of clusters and switches increased with age, whereas in LVF, the number of switches increased in all age groups, but clusters increased only in the older group. Structural equation model analyses showed that oral and written language, verbal memory and inhibitory control are associated with VF performance and IQ, while age mediated VF performance. The results indicate a different development pattern between LVF and SVF in the number of words produced and in clustering and switching, with the latter predicting VF performance in words produced. VF development is shown to depend on language, memory and inhibitory control. Our results have important implications to clinical neuropsychology.

Pervasive autobiographical memory impairments in Huntington’s disease

Autobiographical memory dysfunction is a pervasive feature of neurodegenerative disorders, but less is known about the integrity of autobiographical memory in Huntington’s disease (HD). Deficits in anterograde verbal episodic memory on traditional neuropsychological tests have been detected in HD, however, whether personally-relevant autobiographical retrieval is also affected is unknown. We examined autobiographical memory performance in 26 participants genetically confirmed to have HD who were in the peri-manifest stage of the disease (including 12 in the late premanifest stage and 14 who were early diagnosed), and 24 matched controls using the Autobiographical Interview (AI), a semi-structured interview assessing retrieval of autobiographical details from discrete epochs across the lifetime. Relative to controls, people with HD exhibited global episodic autobiographical memory impairments, regardless of recency or remoteness of the memory being retrieved. While specific cues bolstered the retrieval of episodic (internal) details in HD participants, their performance remained significantly below that of controls. Moreover, following probing, people with HD retrieved more extraneous (external) details not directly related to the autobiographical event they originally retrieved, including semantic details, repetitions, and metacognitive statements. Our results reveal marked autobiographical memory dysfunction in HD, not directly attributable to strategic retrieval deficits, and suggest that autobiographical memory impairment may represent an overlooked feature of the cognitive phenotype of HD.