In times of globalization, national economy reforming and intensification of integration processes the level of competitiveness of industrial enterprises is estimated by many factors, the key of them is innovation activity. Due to innovation the business entity has got an opportunity to strengthen its market positions, improve figures of economic efficiency and create big added value. At the same time results of innovation activity shall target at production and economic work of industrial enterprises and foster supply of new highly-technological goods and services to market, which can be provided by strategic planning. The efficiency of its implementation promotes successful introduction of innovation on market and obtaining sustainable competitive advantages. The author analyzed and studied challenges of strategic planning of innovation development and put forward methods of elaborating the system of strategic planning for diversification of highly-technological enterprises of Russian economy.