The impact of testing loads and deflection of samples made of polymeric materials used in the field of medical engineering after the steam sterilization process were investigated. The research was carried out on samples with standard geometry, according to PN-EN ISO 179-1, which were produced in two different printing configurations relative to the coordinate system of 3D printers using the extrusion additive process. Polymers used are polyether ether ketone (PEEK), MED610, polylactide acid and photocurable resin. The results regarding strength properties were analysed based on measurements of the deflection arrow during straight bending. The photocurable resin showed the smallest deformation, polylactic acid the highest. It is worth noting, each material had a different dependencies during the load test. From results it is concluded, that print orientation, material type and sterilization have significant impact on strength and deformation of polymers.