Story Recall Research Articles

Investigating measurement invariance of the IDS-2 intelligence scales between migrant and non-migrant groups

Intelligence plays a crucial role in various aspects of human life, impacting health, academic achievement, and socio-economic success. However, cultural and linguistic disparities in intelligence testing pose challenges, particularly for individuals from migrant backgrounds. This study replicates and extends the landmark study by Wicherts and Dolan (2010) exploring measurement invariance of the German language intelligence test, the Intelligence and Development Scales – 2 (IDS-2), between children and adolescents from migrant (N = 132) and non-migrant (N = 1898) groups. The results revealed partial strict measurement invariance in the IDS-2 intelligence scale subtests across the examined groups. The breach of full strict measurement invariance is primarily due to intercept differences on the verbally loaded subtests—Naming Categories, Naming Opposites, and Story Recall—highlighting the confounding impact of language complexity on test outcomes. These discrepancies resulted in a cumulative intercept difference disadvantaging migrant participants of approximately 4 IQ points on the Full-Scale IQ Score. The findings indicate that while the IDS-2 scales generally assess intelligence consistently across diverse groups, the influence of language complexity on the verbal subtests may result in a disadvantage for children and adolescents with migration backgrounds. To address these biases, we propose the development of non-verbal and culturally fair intelligence tests.

Response to A Story During Cognitive Screening – Expression of the Inherent Awareness of Survival of Fellow Human Beings

Abstract Background The comprehensive assessment of cognition should include the immediate recall of information as well as that provided after delay. The phenomenon of patients providing intrusions is well recognised in the realm of cognitive assessment. Certain intrusions have been found to recur across patient performances. Methods Retrospective analysis was undertaken of patients (n=9) screened for dementia using the Repeatable Battery for the Assessment of Neuropsychological Status (Pearson) between 2022 and 2024. Data was sourced from MDT notes cataloguing the results of memory tests undertaken whereby the patient had added information regarding loss of life for persons involved in a fire. Data were elicited regarding List Learning (LL) and Recall; Story Memory and Recall, Figure Copy and Recall. The final sheet was used to elicit scores for each category. Results Median age was 76 (range 61-84 years). Male to female was 4:5. Patients were found to make a comment regarding loss of life e.g. ‘nobody was hurt’ where the information did not exist in the original story script. This occurred equally at Story Memory Stage and Story Recall Stage (77.7%). When compared with list and figure copy elements- only one patient also had errors in both LL and memory figure. Six patients had intrusion errors across other elements. Where the story was accentuated in both immediate and delayed recall stages- pts had intrusions in list learning (n=2, 22%) list recall (n=3, 33.3%) but no intrusions on Figure Copy- immediate or delayed. Conclusion Although this cohort of patients was small- each one of them included the status of life lost when given a short story to recite and then recall. These comments occurred both on immediate episodic recall and after delay and were not always associated with a replicated intrusion phenomena across other elements. This inherent interest in the survival of other humans is worth highlighting.

Story Recall in Peer Conflict Resolution Discourse Task to Identify Older Adults Testing Within Range of Cognitive Impairment.

The current study used behavioral measures of discourse complexity and story recall accuracy in an expository discourse task to distinguish older adults testing within range of cognitive impairment according to a standardized cognitive screening tool in a sample of self-reported healthy older adults. Seventy-three older adults who self-identified as healthy completed an expository discourse task and neuropsychological screener. Discourse data were used to classify participants testing within range of cognitive impairment using multiple machine learning algorithms and stability analysis for identifying reliably predictive features in an effort to maximize prediction accuracy. We hypothesized that a higher rate of pronoun use and lower scores on story recall would best classify older adults testing within range of cognitive impairment. The highest classification accuracy exploited a single variable in a remarkably intuitive way: using 66% story recall as a cutoff for cognitive impairment. Forcing this decision tree model to use more features or increasing its complexity did not improve accuracy. Permutation testing confirmed that the 77% accuracy and 0.18 Brier skill score achieved by the model were statistically significant (p < .00001). These results suggest that expository discourse tasks that place demands on executive functions, such as working memory, can be used to identify aging adults who test within range of cognitive impairment. Accurate representation of story elements in working memory is critical for coherent discourse. Our simple yet highly accurate predictive model of expository discourse provides a promising assessment for easy identification of cognitive impairment in older adults. https://doi.org/10.23641/asha.26543824.

B - 118 Exploration of Supplemental Recognition Measures for the RBANS

Abstract Objective RBANS is a widely used cognitive screener that lacks memory recognition measures for 2 recall tasks. Performance on verbal and visual recognition measures, relative to recall, may help inform clinical decision-making and treatment planning. Our pilot project aims to understand how individuals with valid cognitive data and normal memory functioning perform on newly developed RBANS story and figure memory recognition tests. Method Of those referred for outpatient neuropsychological assessment at a veterans hospital between 2017–2024, 89 received the newly established recognition measures as part of their clinical evaluation. Our analysis included veterans that displayed valid profiles (TOMM trial 1 ≥ 45, n = 53). Assessment occurred 30% face-to-face and 70% telehealth. In addition to key demographic factors listed in table 1, race/ethnicity breakdown included: 92% White, 4% Black, 2% Asian, 2% Hispanic. These veterans were subdivided into 3 intact memory groups: list recall (≥ 25%ile, n = 31), story recall (≥ 25%ile, n = 37), figure recall (≥ 25%ile, n = 42) to determine average recognition performances across domains. Results The individuals with valid cognitive data and normal memory recall performed as listed in table 1. Although our novel story and figure recognition measures differ from those published in Duff et al. (2021), our pilot project data largely overlapped with their reported findings despite demographic differences. Conclusion(s) These novel recognition scores can help establish normal story and figure recognition performance to assist with clinical diagnosis and treatment planning. With greater and more diverse samples, we may be able to establish relative cut points for expected recognition memory performances across intact, amnestic/cortical, and vascular/subcortical.

B - 92 Memory Rehabilitation Following Stroke and Traumatic Brain Injury

Abstract Objective Several Meta analyses suggest mixed but objective support for internal strategies. Typically, successful rehabilitation involves at least 8 hour of memory training and often results in 0.25 to 0.50 standard deviation (SD) improvements depending on how long post injury. Intervention dose, strategies, level of impairment, and patient self-awareness and motivation all appear relevant. Methods Data is taken from 21 continuous referrals. Three individuals did not want to work on memory strategies, so their data was separated from the rest. Participants: 18 individuals with acquired brain injuries, with an average age of 51.6 and about 15 years of education, who were 76.6 days post brain injury. Intervention: Each individual was involved in 8 weeks of transdisciplinary rehabilitation. Many goals were addressed and memory rehabilitation was treated via 1 or 2 weekly sessions with a neuropsychologist. Internal and external strategy use was taught. Individuals received 8 to 10 hours of memory rehabilitation involving repetitive practice of clustering, semantic clustering, organizing information into sentences or stories, rhyming, and acronyms. Results Delayed List Recall significantly improved from standard scores of 73.5 to 89.7 and the delayed Story Recall improved from 75 to 90. The mean improvement was nearly 1 standard deviation across measures. Conclusions Individuals showed significant improvement in immediate and delayed recall memory scores. These individuals showed more than 0.5 SD short-term memory (STM) gain and also self-reported improved STM. Durability of gains was not measured in follow-ups. These interventions improve memory skills, but not all patients choose to participate in this type of treatment.

Scoring story recall for individual differences research: Central details, peripheral details, and automated scoring.

Story recall is an episodic memory paradigm that is popular among researchers interested in the effects of aging, disease, and/or injury on memory functioning; it is less popular among individual-differences researchers studying neurotypical young adults. One reason differential psychologists may favor other episodic memory paradigms is that the prospect of scoring story recall is daunting, as it typically requires manually scoring hundreds or thousands of freely recalled narratives. In this study, I investigated two questions related to scoring story recall for individual differences research. First, whether there is anything to gain by scoring story recall for memory of central and peripheral details or if a single score is sufficient. Second, I investigated whether scoring can be automated using computational methods-namely, BERTScore and GPT-4. A total of 235 individuals participated in this study. At the latent variable level, central and peripheral factors were highly correlated (r = .99), and the two factors correlated with external factors (viz., fluid intelligence, crystallized intelligence, and working memory capacity) similarly. Regarding automated scoring, both BERTScore and GPT-4 derived scores were strongly correlated with manually derived scores (r ≥ .97); additionally, factors estimated from the various scoring methods all showed a similar pattern of correlations with the external factors. Thus, differential psychologists may be able to streamline scoring by disregarding detail type and by using automated approaches. Further research is needed, particularly of the automated approaches, as both BERTScore and GPT-4 derived scores were occasionally leptokurtic while manual scores were not.

Story recall performance and AT classification via positron emission tomography: A comparison of logical memory and Craft Story 21

BackgroundEarly detection of Alzheimer's disease (AD) is one of the critical components of the global response to the growing dementia crisis. Analysis of serial position performance in story recall tests has yielded sensitive metrics for the prediction of AD at low cost. In this study, we examined whether serial position markers in two story recall tests (the logical memory test, LMT, and the Craft Story 21 test, CST) were sensitive to cross-sectional biomarker-based assessment of in vivo neuropathology. MethodsParticipants were selected from the Wisconsin Registry of Alzheimer's Prevention (n = 288; WRAP) and the Alzheimer's Disease Research Center (n = 156; ADRC), both from the University of Wisconsin–Madison. Average age at PET was 68.9 (6.7) and 67.0 (8.0), respectively. Data included tau and PiB PET, and LMT for WRAP participants and CST for ADRC participants. Two sets of Bayesian analyses (logistic regressions and ANCOVAs) were conducted within each cohort, separately. ResultsResults indicated that the A+T+ classification was best predicted, cross-sectionally, by the recency ratio (Rr), indexing how much of the end of the story was forgotten between initial learning and delayed assessment. Rr outperformed traditional scores and discriminated between A+T+ and A+T−/A-T-, in both cohorts. ConclusionsOverall, this study confirms that serial position analysis of LMT and CST data, and particularly Rr as an index of recency loss, is a valuable tool for the identification of in vivo tau pathology in individuals free of dementia. Diagnostic considerations are discussed.

Cognition Mediates the Association Between Cerebrospinal Fluid Biomarkers of Amyloid and P-Tau and Neuropsychiatric Symptoms.

Neuropsychiatric symptoms (NPS) can be an early manifestation of Alzheimer's disease (AD). However, the associations among NPS, cognition, and AD biomarkers across the disease spectrum are unclear. We analyzed cross-sectional mediation pathways between cerebrospinal fluid (CSF) biomarkers of AD (Aβ1-42, p-tau181), cognitive function, and NPS. Primary models included 781 participants from the National Alzheimer's Coordinating Center (NACC) data set who had CSF analyzed for AD biomarkers using Lumipulse. NPS were assessed with the Neuropsychiatric Inventory Questionnaire (NPI-Q). We assessed cognition with the harmonized MMSE/MoCA, as well as neuropsychological tests sensitive to AD pathology: story recall, naming, animal fluency, and Trails B. The Clinical Dementia Rating (CDR®) scale assessed dementia severity. Mediation models were estimated with Kemeny metric covariance in a structural equation model framework, controlling for age, education, sex, and APOEɛ4. The sample was older adults (M = 73.85, SD = 6.68; 49.9% male, 390; 27.9% dementia, 218) who were predominantly white (n = 688, 88.1%). Higher p-tau181/Aβ1-42 ratio predicted higher NPI-Q, which was partially mediated by the MMSE/MoCA and, in a second model, story recall. No other pathway was statistically significant. Both the MMSE/MoCA and NPI-Q independently mediated the association between p-tau181/Aβ1-42 ratio and CDR global impairment. With dementia excluded, p-tau181/Aβ1-42 ratio was no longer associated with the NPI-Q. NPS may be secondary to cognitive impairment and AD pathology through direct and indirect pathways. NPS independently predict dementia severity in AD. However, AD pathology likely plays less of a role in NPS in samples without dementia.

Neuropsychological profile associated with financial exploitation vulnerability in older adults without dementia

Objective: Reports of financial exploitation have steadily increased among older adults. Few studies have examined neuropsychological profiles for individuals vulnerable to financial exploitation, and existing studies have focused on susceptibility to scams, one specific type of financial exploitation. The current study therefore examines whether a general measure of financial exploitation vulnerability is associated with neuropsychological performance in a community sample. Methods: A sample (n = 116) of adults aged 50 or older without dementia completed a laboratory visit that measures physical and psychological functioning and a neuropsychological assessment, the Uniform Data Set-3 (UDS-3) and California Verbal Learning Test-II. Results: After covarying for demographics, current medical problems, financial literacy, and a global cognition screen, financial exploitation vulnerability was negatively associated with scores on the Multilingual Naming Test, Craft Story Recall and Delayed Recall, California Verbal Learning Test-II Delayed Recall and Recognition Discriminability, Phonemic Fluency, and Trails B. Financial exploitation vulnerability was not associated with performance on Digit Span, Semantic Fluency, Benson Complex Figure Recall, or Trails A. Conclusions: Among older adults without dementia, individuals at higher risk for financial exploitation demonstrated worse verbal memory, confrontation naming, phonemic fluency, and set-shifting. These tests are generally sensitive to Default Mode Network functioning and Alzheimer’s Disease neuropathology. Longitudinal studies in more impaired samples are warranted to further corroborate and elucidate these relationships.

Memory function in autoimmune encephalitis: a cross-sectional prospective study utilising multiple memory paradigms

Background and objectiveAutoimmune encephalitis (AE) is often associated with clinically significant memory impairment. This study aimed to evaluate memory in a cross-sectional prospective AE cohort using multiple memory paradigms.Methods52 patients (50% seropositive) meeting Graus criteria for possible AE were prospectively recruited between October 2019 and August 202. A comprehensive examination of memory was performed, including tests of supraspan verbal memory (list learning), logicosemantic memory (story learning), figural memory (learning of geometric designs), and verbal associative learning (verbal paired associates). Memory scores were compared to demographically adjusted normative data. Pattern analysis was conducted to assist in the identification of patterns in memory performances.ResultsMean memory scores were not significantly below the normative mean. At an individual patient level, over 20% of the cohort exhibited impaired delayed figural memory, supraspan verbal memory learning and recall. Observed performances were significantly below expected performance for story learning (p = 0.017) and recall (p = 0.003), figural recall (p < 0.0001), initial acquisition (p < 0.001) and final acquisition of a list (p < 0.001) and all delayed recall measures of the list (p < 0.00001). 54.76% of patients exhibited intact psychometrics, and 16 distinct patterns of impairment emerged, indicating variability in memory outcomes.DiscussionWhile statistical evidence for memory impairment did not emerge at an aggregate level, a proportion of patients present with evidence of abnormal memory performance on psychometrics. Variability in impaired memory measures argues for an individualised patient-focused approach to clinical assessment in AE. Future research should validate these findings with a larger sample size and explore the relationships between memory profiles and other cognitive functions.

A comparison of different connected-speech tasks for detecting mild cognitive impairment using multivariate pattern analysis

ABSTRACT Background It is common for the elderly population to have age-associated cognitive decline and/or develop neurodegenerative diseases such as dementia. Several studies have suggested that classification algorithms based on linguistic features may be useful for the early detection of mild cognitive impairment (MCI). Aims The current study aimed to examine connected-speech performance in people with MCI and cognitively healthy controls (HC). It tests whether patterns of lexical-semantic features extracted from these tasks could distinguish participants with MCI from HC, using univariate and multivariate analyses. Methods & procedure We selected 16 English-speaking participants with MCI and 16 matched HC from the Delaware corpus. Four connected-speech tasks (a picture description, a story narrative, a story recall, and a procedural narrative). Eight lexical-semantic features were selected for analyses. Outcomes & results Univariate analyses showed inter-group differences in revision ratio, core lexicon, or open/closed class words ratio, depending on the task. Multivariate pattern analysis (MVPA) results demonstrated that the story recall task is the only task that can discriminate the two groups above chance. Conclusion To conclude, results showed that connected-speech tasks have the potential to detect subtle language changes in people with MCI. In particular, the story recall task had the potential to predict the group of a participant (MCI or HC).

Enhanced Learning and Memory in Patients with CRB1 Retinopathy.

Neuropsychological tests of cognitive function were used to test individuals with CRB1 and non-CRB1 retinopathies and compare results with a standardised normative dataset. CRB1 retinopathy subjects significantly outperformed those with non-CRB1 retinopathy in list learning tasks of immediate (p = 0.001) and delayed memory (p = 0.007), tests of semantic verbal fluency (p = 0.017), verbal IQ digit span subtest (p = 0.037), and estimation test of higher execution function (p = 0.020) but not in the remaining tests of cognitive function (p > 0.05). CRB1 retinopathy subjects scored significantly higher than the normal population in all areas of memory testing (p < 0.05) and overall verbal IQ tests (p = 0.0012). Non-CRB1 retinopathy subjects scored significantly higher than the normal population in story recall, verbal fluency, and overall verbal IQ tests (p = 0.0016). Subjects with CRB1 retinopathy may have enhanced cognitive function in areas of memory and learning. Further work is required to understand the role of CRB1 in cognition.

The mouth of God: the impact of religious training on story recall in Tibetan Buddhists

ABSTRACT Numerous studies have indicated that religious systems have a profound impact on individuals’ perceptions, emotions, and cognitive processes. The current research investigates the effects of religious upbringing and training on story recall in Tibetan Buddhists, specifically focusing on the Kagyu and Nyingma traditions. Based on the observation that the lineage of the Kagyu emphasizes a continuity of oral instructions passed on from master to student, we predicted that Kagyu monks would demonstrate a higher ability of recalling stories than Nyingma monks, even in a non-religious context. Supporting our theoretical perspective, the results showed that Kagyu monks recalled a significantly greater proportion of a folktale than Nyingma monks under the oral-presentation condition. However, the two groups of participants showed no significant differences in their story-recall performance under the written-presentation condition. These findings are consistent with the core values of the Kagyu tradition that gives central prominence to the oral dissemination of Buddhism teachings. This study presents the first empirical evidence for the notion that religious differences are associated with meaningful variations in narrative and memory skills for stories.

Diffusion imaging markers of accelerated aging of the lower cingulum in subjective cognitive decline.

Alzheimer's Disease (AD) typically starts in the medial temporal lobe, then develops into a neurodegenerative cascade which spreads to other brain regions. People with subjective cognitive decline (SCD) are more likely to develop dementia, especially in the presence of amyloid pathology. Thus, we were interested in the white matter microstructure of the medial temporal lobe in SCD, specifically the lower cingulum bundle that leads into the hippocampus. Diffusion tensor imaging (DTI) has been shown to differentiate SCD participants who will progress to mild cognitive impairment from those who will not. However, the biology underlying these DTI metrics is unclear, and results in the medial temporal lobe have been inconsistent. To better characterize the microstructure of this region, we applied DTI to cognitively normal participants in the Cam-CAN database over the age of 55 with cognitive testing and diffusion MRI available (N = 325, 127 SCD). Diffusion MRI was processed to generate regional and voxel-wise diffusion tensor values in bilateral lower cingulum white matter, while T1-weighted MRI was processed to generate regional volume and cortical thickness in the medial temporal lobe white matter, entorhinal cortex, temporal pole, and hippocampus. SCD participants had thinner cortex in bilateral entorhinal cortex and right temporal pole. No between-group differences were noted for any of the microstructural metrics of the lower cingulum. However, correlations with delayed story recall were significant for all diffusion microstructure metrics in the right lower cingulum in SCD, but not in controls, with a significant interaction effect. Additionally, the SCD group showed an accelerated aging effect in bilateral lower cingulum with MD, AxD, and RD. The diffusion profiles observed in both interaction effects are suggestive of a mixed neuroinflammatory and neurodegenerative pathology. Left entorhinal cortical thinning correlated with decreased FA and increased RD, suggestive of demyelination. However, right entorhinal cortical thinning also correlated with increased AxD, suggestive of a mixed pathology. This may reflect combined pathologies implicated in early AD. DTI was more sensitive than cortical thickness to the associations between SCD, memory, and age. The combined effects of mixed pathology may increase the sensitivity of DTI metrics to variations with age and cognition.

Mothers' negative focus during memory‐sharing conversations is linked to negative interpretation and memory biases in young children

AbstractParent‐guided reminiscing helps children learn how to interpret and recollect personal experiences. These interpretive abilities are important because many experiences are ambiguous, and a tendency toward negative interpretation is associated with emotional disorders. Here, we explore whether naturally‐occurring variations in parent‐guided reminiscing are associated with children's interpretation and recall of novel ambiguous events. Mothers and their children (aged 5–6 years) reminisced about three shared negative events. Next, children were read several stories that described ambiguous social situations and were asked to invent endings that involved making an inference about motives of others in the stories. Later, children were asked questions to elicit story recall. Mothers who used more negative terms during reminiscing had children who were more likely to invent negative story endings and distort story recall negatively. Thus, mothers who frame memory‐sharing conversations with children negatively might put them at risk for developing negative interpretation and memory biases.

Cognitive performance in children and adolescents with primary hypertension and the role of body mass.

Primary hypertension has been shown to affect cognitive functions in adults but evidence in the pediatric population remain scarce and equivocal. We aimed to compare cognitive functioning between children diagnosed with primary hypertension and normotensive controls, with a focus on the role of different blood pressure (BP) parameters and body mass. We conducted a single-center, prospective, cross-sectional study of children and adolescents (6-17 years old) with primary hypertension and age- and sex-matched normotensive controls. All participants underwent office BP, ambulatory BP monitoring (ABPM), and central BP measurements using an oscillometric device. Neurocognitive assessment consisted of evaluation of (i) intelligence quotient (IQ), (ii) categorical and phonemic fluency, (iii) verbal memory (verbal-logical story recall), and (iv) non-verbal computerized cognitive assessment. The study included a total of 59 patients with primary hypertension (14 ± 3 years) and 37 normotensive controls (14 ± 3 years). Participants in the primary hypertension group had a significantly higher body mass index z-score (BMIz: 2.1 ± 1.4 vs. 0.7 ± 0.9, p < 0.001), and 85% received antihypertensive therapy. Participants with primary hypertension showed worse performance in the domains of reaction speed, attention and processing speed, visual memory, new learning, and phonemic fluency. After adjusting for BMIz, only the differences in the reaction speed tasks remained significant. None of the BP parameters was associated with cognitive outcomes after adjustment for age, sex, and BMIz. BMIz associated with tasks of visual memory, new learning, spatial planning, and working memory, independent of age and sex. Children and adolescents diagnosed with primary hypertension exhibit worse performance in the cognitive domains of reaction speed, attention, processing speed, visual memory, and new learning. These differences to healthy controls can be partially attributed to accompanying increase of body mass.

The developmental path of metacognition from toddlerhood to early childhood and its influence on later memory performance.

Recently, several studies have suggested that metacognition emerges early in infancy and toddlerhood. However, to date, the developmental trajectory of these early metacognitive monitoring and control processes and their influence on children's later memory functioning remains poorly understood. The aim of this study was to longitudinally document the development of metacognition between the ages of 2.5 and 4.5 years and to examine the link between these early metacognitive skills and later memory performance. To do so, 69 children initially aged 29-33 months old (NT0 = 69; 32 females; Mage = 32.3 months; SD = 1.6) were tested at three time points (12-month intervals) with a recognition memory paradigm designed to assess both metacognitive monitoring, through retrospective confidence judgment, and metacognitive control, through a cue selection task (i.e., children had the opportunity to ask for a cue to help them change their memory decision). In addition, at the last session, an episodic memory task (story recall) was also administered. Our results revealed an improvement in monitoring and control processes between 2.5 and 4.5 years with above-chance performance from around age 3.5. Mixed-effects modeling also indicated that metacognitive monitoring at ages 2.5 and 4.5, but not-unexpectedly-metacognitive control, was related to children's memory performance at age 4.5. Overall, our results provide evidence to enhance our understanding of the developmental course of metacognition from toddlerhood to early childhood and suggest that metacognitive processes are involved in memory performance much earlier than had previously been shown. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

The Impact of Emotion Regulation Strategy on Recall for Emotional Versus Non-Emotional Stories in Older Adults

The Impact of Emotion Regulation Strategy on Recall for Emotional Versus Non-Emotional Stories in Older Adults

The Effects of Prospective Memory Intervention on Language Ability and Activities of Daily Living in the Elderly with Alzheimer’s Disease

Objectives: Alzheimer’s Disease (AD) is characterized by an early decline in memory and cognitive functions, leading to impairments in language abilities and difficulties in communication as the disease progresses. Therefore, the need for early diagnosis and intervention in AD is considered critical; and maintaining and improving Prospective Memory (PM) is reported to aid in enhancing complex cognitive functions. This study aimed to explore the changes observed before and after PM intervention using External Memory Aids (EMA) in elderly individuals with AD.Methods: This study was conducted with 7 elderly individuals with mild AD, over three weeks with 12 sessions, four times a week. The intervention was based on a protocol consisting of three stages using the Prospective Memory Task (PMT) developed for this research: 1) reading texts, 2) answering wh-questions, and 3) utilizing EMA.Results: Significant improvements were showed after the intervention in performance of intervention and non-intervention PMT, immediate recall of words and story, naming, and K-MMSE, indicating the generalized effects of the intervention. However, there were no significant improvements in delayed recall, verb fluency and Activities of Daily Living.Conclusion: The use of EMA in PM intervention appeared to positively impact the language abilities and overall cognitive functions of elderly AD patients, suggesting that the activated PM through the intervention could lead to improvements in general cognitive functions.

Sex-Specific Association of Body Mass Index with Hippocampal Subfield Volume and Cognitive Function in Non-Demented Chinese Older Adults.

Recent research suggests a possible association between midlife obesity and an increased risk of dementia in later life. However, the underlying mechanisms remain unclear. Little is known about the relationship between body mass index (BMI) and hippocampal subfield atrophy. In this study, we aimed to explore the associations between BMI and hippocampal subfield volumes and cognitive function in non-demented Chinese older adults. Hippocampal volumes were assessed using structural magnetic resonance imaging. Cognitive function was evaluated using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). A total of 66 participants were included in the final analysis, with 35 females and 31 males. We observed a significant correlation between BMI and the hippocampal fissure volume in older females. In addition, there was a negative association between BMI and the RBANS total scale score, the coding score, and the story recall score, whereas no significant correlations were observed in older males. In conclusion, our findings revealed sex-specific associations between BMI and hippocampal subfield volumes and cognitive performance, providing valuable insights into the development of effective interventions for the early prevention of cognitive decline.