The current probabilistic seismic demand analysis of structures predominantly considers the correlation between the ground motion intensity measure (IM) and structural seismic demand, but fails to effectively capture regional source characteristics. It is essential to integrate earthquake engineering with seismic response of structures using source parameters to quantify regional ground motion uncertainties and determine appropriate IMs. This study presented a probabilistic seismic demand analysis method for structures based on earthquake scenarios, characterized by 1) utilizing the stochastic finite-fault method to simulate ground motions at a specific site instead of employing multiple seismic waves from different source areas, and 2) incorporating the correlation between IMs and the key indicator of source parameters, stress drop, into the probabilistic seismic demand analysis. Taking a continuous girder bridge as an example, the performance of the stress drop and 14 individual IMs in predicting the longitudinal seismic demand and reflecting source characteristics was evaluated. The results revealed that it was difficult to establish a reliable relationship between the stress drop and structural seismic demand. Owing to the complexities of ground motion and structural parameters, the individual IMs were challenging to effectively capture their characteristics simultaneously. Therefore, composite IMs have been proposed to cover the characteristics of both the source and seismic demand. The optimal solutions were derived using a multi-objective genetic algorithm, which exhibited desirable capabilities in both aspects, providing a comprehensive guide for the seismic performance assessment of regional transportation networks.
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