Steps Of Meta-analysis Research Articles

The Effect of Thyroid Dysfunction on Pregnancy Outcome: Systematic Review and Meta-Analysis

Thyroid dysfunction during pregnancy certain impact on pregnancy outcomes, and neonatal growth. The incidence of pregnancy with hyperthyroidism ranges from 0.5% to 1%, leading to adverse pregnancy outcomes such as abortion, premature delivery, stillbirth, gestational hypertension, placental abruption, and premature rupture of membranes. This study aimed to analyzed the effect thyroid dysfunction on pregnancy outcomes. This was a systematic review and meta-analysis. The PICO research question as follows. Population: Pregnancy; Intervention: Dysfunction Thyroid; Comparison: Thyroid Normal; Outcome: Effect of Pregnancy. The articles were obtained from four databases: PubMed, Web of Science, Springer, and Science Direct. The Keywords were “Thyroid Dysfunction” OR “Pregnancy” OR “Outcomes” AND “Prospective Cohort” AND “Retrospective comparative”. Full text article in English with study design Cohort and retrospective comparative from 2012 to 2022, were included in this study. The steps of meta-analysis followed PRISMA flow diagram. The Articles were analyzed by the Review Manager 5.4 application A total 11 cohort and retrospective comparative from India, Israel, Denmark, Pakistan, America, Finland, and China were selected for a systematic review and meta-analysis. the data collected showed that effect of thyroid disfunction on pregnancy outcome among preterm birth by 0.87 times and was statistically significant (SMD=0.87, 95% CI=0.87 to 0.93; P<0.00001); Pre-Eclampsia by 0.70 times (SMD=0.70, 95% CI=0.50 to 0.96; P=0.03); Placenta abruption by 0.27 times (SMD=0.27, 95% CI=0.19 to 0.38; P<0.00001); Fetal Distress by 0.77 times (SMD=0,77, 95% CI=0.68 to 0.86; P<0.00001); Post-partum Hemorrhage by 0.57 times (SMD=0.57, 95% CI= 0.37 to 0.87; P<0.009).

Meta-Analysis of the Influence of the Inquiry Model on Student Learning Outcomes

Student success in learning is very necessary to see the extent to which students are able to solve problems. However, it turns out that student learning outcomes are still low. The solution to overcome this problem is to apply the inquiry learning model during learning. This research aims to determine the effect of the inquiry learning model on student learning outcomes. The application of the inquiry model is seen from the level of education and physics and science lessons. This type of research is meta-analysis. Meta-analysis is research carried out by summarizing research data, reviewing and analyzing research data from several previously existing research results. This research article consists of 11 articles that have ISSN. The instruments used are category codes and effect size calculations. The steps of meta-analysis are conducting a literature review, collecting data, researching and assessing articles, analyzing and interpreting articles, and compiling report results. The data analysis technique in this research is to calculate the magnitude of the effect using a formula based on the mean. From the data analysis carried out, two research results can be stated. First, the application of the inquiry learning model has a significant effect on the level of education and subject matter, especially physics and science.

Effects of Inquiry Learning on Students' Science Process Skills and Critical Thinking: A Meta-Analysis

The skills of a student are needed to achieve success in learning and everyday life. However, their skills were still low. Solution to solve this problem is to apply an inquiry learning model during learning. This research aims to determine the effect of the inquiry learning model on students' science process skills and critical thinking which is reviewed based on the level of education, subject matter and type of inquiry learning model. This type of research is a meta-analysis. Meta-analysis is research conducted by summarizing research data, reviewing and analyzing research data from several pre-existing research results. The articles of this research consisted of 20 articles that already had an ISSN. The instruments used were category codes and effect size calculations. The steps of meta analysis are conducting a literature review, collecting data, researching and assessing articles, analyzing and interpreting articles and compiling report results. The data analysis technique in this study is to calculate the magnitude of the effect using the formula (1981) based on the mean, standard deviation, and t-test. From the data analysis carried out, it can be stated that four research results. First, the application of the inquiry learning model has a significant effect on science process skills and critical thinking skills based on level education, learning materials, and types of inquiry learning model.

META ANALYSIS OF THE EFFECT OF THE USE OF MODULE ON STUDENTS' CRITICAL THINKING ABILITY IN PHYSICS AND SCIENCE COURSES

The twenty-first century is evolving at an incredible rate.. The development of information and communication technology in all aspect of life, including in the learning process has entered the modern era. The ablility to think critically and solve problems skill (problem solving skill) are important skills for surviving in the twenty-first century. The real condition found in the field were that students' critical thinking skills are relatively low during the teaching and learning process. One solution to overcoming this problem is to use learning media namely in the form of modules. Then, it is necessary to have further research on the Module. Meta-analysis is the term for this type of study. Researchers undertake meta-analysis by synthesizing research data, examining, and analyzing research data from a number of previously published studies. Conducting a literature review, gathering data, studying and assessing papers, analyzing and interpreting articles, and producing report results are all steps in meta-analysis. The necessary statistical data must be included in the article, according to the standard. From the data analysis carried out, it can be stated three results of this research. First, the use of the module has a significant effect on the senior high school level compared with an average effect of 0.931 to junior high school level. Second, the use of the module has a significant effect on the Newton’s Gravity material with an average effect of 3.742. Third, the use of the module has a significant effect by using a Contextual Teaching and Learning Model and saintific approach.

Role of maintenance strategies in advanced epithelial ovarian cancer: a systematic review, network meta-analysis and cost-effectiveness analysis protocol

IntroductionDifferent maintenance strategies have shown efficacy in patients with advanced ovarian cancer, but without drawing any conclusion on which strategy is preferred. Therefore, we will conduct a network meta-analysis and...

A standardized checklist on meta-analysis reporting in the open science era

Meta-analysis is a crucial tool for accumulating evidence in basic and applied research. In the open science era, meta-analysis becomes an important way for integrating open data from different sources. Meanwhile, because of researchers’ high degree of freedom introduced by multiple-steps and multiple-choices in each step of meta-analysis, the openness and transparency are crucial for reproducing the results of meta-analysis. To reflect the transparency and openness of meta-analysis reports published in Chinese journals and improve the transparency and openness of future meta-analysis by Chinese researchers, we developed a Chinese version of a checklist for meta-analysis (Preferred Reporting Items for Open and Reproducible Meta-analysis, PRIOR-MA), which was based on the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) and the principle of openness and transparency. We then surveyed the methods and results of 68 meta-analysis papers published in mainstream Chinese psychological journals in the last five years. Our results revealed that the openness and transparency of Chinese meta-analysis reports need to be improved, especially in the following aspects: the date/time and limitation of literature search, the details of screening and data collection, the flow chart of article screening, the details of effect size transformation, and the evaluation of individual research bias. The checklist, which lists almost all aspects that an open meta-analysis should include, can be used as a guide for future meta-analysis. This paper provides a comprehensive checklist (PRIOR-MA) for open meta-analysis, and provides a reference for future meta-analytic research.

Supporter Profiling in Recycled Water Reuse: Evidence from Meta-Analysis

Recycled water is considered as a viable alternative water source, and its use is of great significance in dealing with the shortage of water resources. However, it is often rejected by the public during its promotion. To identity the common social attributes of proponents of recycled water, it is essential to study the profiled customers’ willingness to accept recycled water during the most difficult initial stage of promoting recycled water use projects. A meta-analysis was conducted in this study to deal with data concerning the influence of different social demographic factors on the public’s acceptance of recycled water use. Three steps of meta-analysis were mainly used in this paper. First, a random-effect model was used to measure the effect size of influencing factors, such as age, gender, and education. It was found that younger women were more likely to accept recycled water use than older men, and individuals with higher education were more willing to accept recycled water. Then, a cumulative meta-analysis showed that it was feasible to select young women with higher education as target profile customers in the initial stage of recycled water promotion. Finally, according to a meta-regression analysis, it was revealed that different research areas and selected model methods have important regulatory effects on the intention of the target population to use recycled water.

Minimally invasive drainage versus open surgical debridement in SAP/SMAP \u2013 a network meta-analysis

BackgroundThe efficacy of some therapeutic methods (open surgical debridement (OSD), conservative treatment (CST) and minimally invasive drainage (MID)) for severe acute pancreatitis (SAP) and moderately severe acute pancreatitis (MSAP) has been widely evaluated. However, the results remained controversial. We performed this study to illuminate whether any difference in incidence exists on patients with SAP/MSAP treated with OSD and MID.MethodsEligible articles were collected base of a comprehensive review of PUBMED, EMBASE, COCHRANE, CKNI and WANGFANG for published randomized controlled trials. Two steps of meta-analysis were performed, routine pair-wise meta-analysis and network meta-analysis.ResultsThirteen studies were included in this study. Participants were classed as 5 groups, CST, early MID (EMID), late MID (LMID), early OSD (EOSD) and late OSD (LOSD). And MID contains endoscopic drainage (ESD), percutaneous catheter drainage (PCD) and minimally invasive surgery (MIS). Compared with CST, MID could decrease both mortality and multiple organ dysfunction syndrome (MODS) rate but OSD couldn’t. Both EMID and MID can significantly decrease the mortality and MODS rate compared to CST. PCD might be most likely to have a benefit compared to CST.ConclusionExisting evidence for the use of MID in SAP/MSAP is reliable and it can be used as early treatment. OSD, if necessary, should be avoided or delayed as long as possible.

Suicidal ideation in bully victimized school children and adolescents:a meta analysis

In the recent years there has been increased attention to the association of bullying involvement and suicidal ideation in school going children and adolescents. This meta analytic study was conducted by online searching of articles using Pub Med data bases and Google scholar. Total 21 both USA based and non USA based studies were included and sample size were 219,929. We used the research term ‘bullying’, ‘suicide’, ‘children’, ‘adolescence’ , ‘school bullying’ , ‘suicidal ideation’ and by using the term ‘cross sectional studies’, from 2010 to 2013 for studies identification. One predictor bully victimization and one outcome suicidal ideation were analyzed. Inverse weighted average was measured to see the effect size and forest plot was applied for data presentation. All the steps of meta analysis were followed. Our pooled data showed increase risk of suicidal ideation in bully victim.The results showed that odd ratio of suicidal ideation was 2.18 in bully victims in USA based studies and 95% CI 2.12 to 2.24 and odds ratio of non USA based studies was 2.31 and 95% CI 1.73 to 3.09 whereas combined USA and non USA studies odd ratio was 2.6 and 95% CI 2.20 to 3.22. Findings concluded that bully victims had the increased risk of suicidal ideation.Bang J Psychiatry June 2015; 29(1): 35-40

Meta-analysis in marketing research

Meta-analysis is a method that allows us to accomplish such a work by combining the results of several studies in order to make an objective synthesis following precise stages. With the help of meta-analysis, we can quantify a global result for the entire studies taken into consideration and obtain a more precise response and a more acceptable generalization. This paper focuses on the steps of meta-analysis on resumed data, which are used more frequently, because they can easily tend towards exhaustiveness. The synthesis work has to be standardized. It consists in four stages: studies’ research, selection, data extraction and analysis. Its feasibility is linked to the existence of a sufficient number of studies that can be included in this meta-analysis. This method has been used in research since 1970 and it became irreplaceable for making recommendations. Its application field is only limited to that of existent studies.

Sağlık Bilimlerinde Meta Analiz

Meta analysis is a statistical analysis of results obtained from independent studies to combine the findings. It provides more powerful and precise estimates than any individual study contributing to the pooled analysis. In this review paper, the definition and aims of meta analysis, the steps of meta analysis and its advantages and negative criticisms towards the meta analysis are given.

Meta-analysis for orthodontists: Part I--How to choose effect measure and statistical model.

Systematic reviews ideally provide a comprehensive and unbiased summary of existing evidence from clinical studies, whilst meta-analysis combines the results of these studies to produce an overall estimate. Collectively, this makes them invaluable for clinical decision-making. Although the number of published systematic reviews and meta-analyses in orthodontics has increased, questions are often raised about their methodological soundness. In this primer, the first steps of meta-analysis are discussed, namely the choice of an effect measure to express the results of included studies, and the choice of a statistical model for the meta-analysis. Clinical orthodontic examples are given to explain the various options available, the thought process behind the choice between them and their interpretation.

メタアナリシス論文における評価基準の作成と分析 ～糖尿病とレニン・アンジオテンシン系阻害薬の関連～

In recent years, evidence-based medicine is practiced in medical care, and meta-analysis is positioned as the highest quality research paper. However, there are no unified criteria to evaluate meta-analysis. Thus, we developed and evaluated objective criteria of meta-analysis paper. Meta-analysis was evaluated from the standpoint of format and quality. Format score was developed based on QUOROM statement. Quality scores were evaluated in each step of meta-analysis. We evaluated meta-analysis for advantageous or adverse effect in the relationship between Renin-angiotensin system (RAS) inhibitor and diabetes mellitus. Research articles either in English or Japanese were searched in PubMed and the Cochrane Library in July 2009. Fifty-five studies were evaluated for format and quality score. Format score was 64.5+/-25.3% (Mean+/-S.D.), and quality score was 57.1+/-21.6%. After plotting each score along the X-Y coordinate, format score was correlated with quality score (R2=0.702, p<0.001). In studies with quality score of 70% or higher, RAS inhibitor prevented new-onset diabetes mellitus. Angiotensin converting enzyme (ACE) inhibitor reduced risk of myocardial infarction, however, angiotensin receptor blockers (ARB) increased the incidence in odds ratio 1.21 (95%CI: 1.04-1.40). We evaluated meta-analysis by format and quality score, and these factors showed correlation. Therefore, assessment of quality score leads to prompt and reliable evaluation of meta-analysis. According to articles evaluated by quality score, RAS inhibitor showed effectiveness on diabetes mellitus. However, careful attention must be given in ARB therapy on patients with myocardial infarction risk.

МЕТОДИ ТА МЕТОДОЛОГІЯ НАУКОВИХ ДОСЛІДЖЕНЬ У СФЕРІ ПСИХОЛОГІЧНОЇ ДОПОМОГИ

У статті здійснюється огляд методологічних вимог до наукових досліджень у сфері психологічної допомоги. Дається короткий екскурс в історію психотерапевтичних досліджень. Вказуються основні дослідницькі стратегії, серед яких – оцінювання "терапевтичного пакету", оцінювання внеску окремих і додаткових втручань в ефективність "терапевтичного пакету", оцінювання ролі окремих параметрів організації психотерапії та самого терапевтичного процесу, оцінювання характеристик клієнта і терапевта, порівняння ефективності окремих підходів. Коротко окреслюються перспективні напрямки досліджень, зокрема аналіз негативних ефектів психотерапії, її медіаторів та механізмів. Описується сучасний стандарт розвідок у сфері психічного здоров’я – експериментальні рандомізовані контрольовані дослідження, а також основні стратегії їх реалізації: нетерапевтичного контролю, порівняння терапевтичних та звичайних умов, порівняння з плацебо, контролю компонентів терапевтичного проекту, комбінації терапевтичних проектів, порівняння з альтернативами. Висвітлюються особливості застосування та базові кроки мета-аналітичних досліджень, зокрема такі, як концептуалізація, збір даних, кодування змінних, статистичний аналіз, мета-аналітичні висновки та узагальнення. Вказується на роль наукових досліджень у регуляції розвитку психотерапевтичної практики. Згадуються окремі наукові об’єднання та центри, які розвивають наукові дослідження у психотерапії.&#x0D; The overview of the methodological requirements of psychotherapy research and the brief excursion into the history of empirical base psychotherapy are presented in this article. Basic research strategies in the field of psychological help are Treatment Package Strategy, Dismantling Treatment Strategy, Constructive Treatment Strategy, Parametric treatment strategy, Comparative Treatment Strategy, Client and therapist variation strategy and process research strategy. The perspective ways of research are analysis of the negative effects of psychotherapy and investigation ofpsychotherapeutic mediators and mechanisms. Modern standard of research in the field of mental health - randomized controlled trial. Main implementation strategies of RCTs are Wait-list or no-treatment control, Treatment-as-Usual Comparison, Placebo Comparisons, Component Control Designs, Combination Treatment Designs and Comparisons With Bon а Fide Alternatives. Meta-analysis is special kind of psychotherapy research, which involves describing the results of different studies using statistical procedures. Basic steps of meta-analysis are Conceptualization, Data collection, Coding studies, Statistical procedures, Write up meta-analysis. Scientific research have significant role in the regulation of the psychotherapy practice.

A CD-based mapping method for combining multiple related parameters from heterogeneous intervention trials.

Effect size can differ as a function of the elapsed time since treatment or as a function of other key covariates, such as sex or age. In evidence synthesis, a better understanding of the precise conditions under which treatment does work or does not work well has been highly valued. With increasingly accessible individual patient or participant data (IPD), more precise and informative inference can be within our reach. However, simultaneously combining multiple related parameters across heterogeneous studies is challenging because each parameter from each study has a specific interpretation within the context of the study and other covariates in the model. This paper proposes a novel mapping method to combine study-specific estimates of multiple related parameters across heterogeneous studies, which ensures valid inference at all inference levels by combining sample-dependent functions known as Confidence Distributions (CD). We describe the "CD-based mapping method" and provide a data application example for a multivariate random-effects meta-analysis model. We estimated up to 13 study-specific regression parameters for each of 14 individual studies using IPD in the first step, and subsequently combined the study-specific vectors of parameters, yielding a full vector of hyperparameters in the second step of meta-analysis. Sensitivity analysis indicated that the CD-based mapping method is robust to model misspecification. This novel approach to multi-parameter synthesis provides a reasonable methodological solution when combining complex evidence using IPD.