ABSTRACT Background: Periapical extrusion of debris for root retreatment will effectively improve the posttreatment inflammation and pain. The aim of this study was to investigate the extruded debris for root retreatment using XP shaper and ProTaper files. Materials and Methods: In his experimental laboratory study, 40 extracted human maxillary molars were used in this laboratory study. After disinfection and equalization of length, the samples were treated with a passive step-back technique and dressed. The samples placed in the tubes for retreatment were divided into four groups: (1) XP shaper file and hypochlorite, (2) XP shaper file and ethylenediaminetetraacetic acid (EDTA), (3) ProTaper file and hypochlorite, and (4) ProTaper file and EDTA. Then, the teeth were taken out of the tubes, and cleaned to collect the remaining apical debris. The weight of the tube and the extruded debris was measured again. Data were analyzed using the Kruskal–Wallis test (α =0.05). Results: The highest average of extruded debris was related to the XP shaper file with EDTA solution, and the lowest average was related to the ProTaper file with hypochlorite solution. Between the two files used with EDTA and hypochlorite solution, the average debris extrusion of the XP shaper file with EDTA solution was significantly higher (P < 0.05) compared to the ProTaper and XP shaper files with hypochlorite solution (P < 0.05). Conclusion: Regardless of the type of irrigant material, the ProTaper file can be a more suitable option than the XP shaper file for retreatment of the tooth root canal with minimal debris extrusion.
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