Stem Cell Research In India Research Articles

Medico Legal and Ethical Study of Stem Cell Research in India

Stem cells have the ability to produce a large number of specialised cells or tissue by regeneration and differentiation. The cells that regenerate could be known to cure disease or injury. As a result, they are distinguished from other cell types by their ability to replicate themselves. Stem cells offer the potential to develop cell-based therapies. Such type of research could lead to novel and improved treatments for a variety of disorders, including diabetes, spinal cord injuries, Alzheimer's, Parkinson's, and heart disease. Stem cell treatment, also characterized as regenerative medicine, induce the repair mechanism of damaged, diseased, or injured tissue using stem cells and their derivatives. Early-stage embryos are used to obtain human embryonic stem cells. Because human embryonic stem cells are harvested from human embryos, there have been various concerns raised the moral and ethical issues in embryonic stem cell research. On the other hand, reprogramming of somatic cells to make induced pluripotent stem cells, avoids the moral and ethical issues that come with embryonic stem cell research. In human stem cell research in addition to moral issues, informed consent to donate materials, critical downstream research, premature clinical trials and oversight all issues occur. To ensure that stem cell research is carried out in an ethically acceptable way, these ethical and policy issues must be discussed along with scientific challenges. This article examines these challenges and how they are addressed in India are explained.

An Empirical Study on the Legal Issues Surrounding Embryonic Stem Cell Research in India

The discovery of stem cells particularly embryonic stem cells with its possible clinical application has generated great curiosity amongst medical professionals and general public. Embryonic stem cell research has become a challenging issue for biomedical scientists, policy makers and regulatory bodies. The key controversial issue is the determination of moral and legal status of the embryo as embryo stem cell research involves retrieving embryonic tissue from spare embryos leading to their destruction. This embryo that has the full capacity to develop into a human being is sacrificed for the benefit of others. Global regulations monitoring stem cell research are also troubled with similar ethical and moral issues associated with it. The main source of embryonic tissue is the spare or supernumerary embryos created during infertility treatment by artificial reproductive techniques (ART). Sadly, in absence of regulatory provisions to govern them, the field of ART is open for all forms of medical malpraxis bearing direct implications on embryonic stem cell research. This article is an attempt to seek clarity on the concept of embryonic stem cell research and contentious issues associated with it. This is a non-doctrinal study. The researcher has depended on both primary and secondary data. Random sampling has been used to collect the primary data which has been analysed using Frequencies, Chi-Square test and Crosstab method. Secondary data like books, websites, journals and case laws have also been referred to provide a comprehensive and holistic approach towards the study.

Mapping of stem cell research in India during 2009–2014: a bibliometric analysis

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Biopolitical Excess: Techno-Legal Assemblage of Stem Cell Research in India

Stem cell research on cardiac patients at the All India Institute of Medical Sciences (AIIMS), which was disclosed through the media in 2005, created a storm. On the one hand, it was celebrated as a ‘global first in pioneering stem cell medicine’. On the other hand, not only the AIIMS study, but, more broadly, stem cell research and therapy in India was criticised for ‘tall claims [and] questionable ethics’. The responses of the policymakers and regulators in India were equally divergent. How are we to understand the contingency and unpredictability of the regulatory regime in India? The answers to this and other related questions are often presented through a regulatory fix—countries such as India need to tighten their regulatory regime. The need for a legally binding regulatory regime is undeniable; nevertheless, a narrow focus on a regulatory fix fails to explain several issues. In this article, I analyse the stem cell research on cardiac patients at AIIMS. Through a focus on epistemic, ethical and juridical assemblage of stem cell research, I highlight the inescapable contingency in the translation between ‘governmental rationality’ and ‘the practice of government’ and show how this reflects biopolitical excess.

Emerging Structure of Stem Cell Research in India: An Analysis of Publication Output, 1990-2014

Emerging Structure of Stem Cell Research in India: An Analysis of Publication Output, 1990-2014

Stem Cell Treatment as Innovation in Sustaining Socio-Economic Condition in Health Care Sector in India

Stem cell research as a radical innovation in the medical field holds promises for good health and development as its treatment is curable to many diseases. The objectives of this paper is to explore the challenges and scope for establishing Stem Cell Research as one of the affordable branch of medicine in India and to examine whether Stem cell research would face the same ethical and religious hostility in the Indian context as faced by it in other parts of the globe. The methodology would involve the use of secondary data sources in order to understand the scenario of stem cell research in India, with respect to the aforementioned objectives. It is still an emerging field in India, which needs proper funding and good policies for implementation by government authorities and organizations like DST, DBT and ICMR. Several research institutions and biotech companies have been formed with the mandate on bringing stem cell research outcomes from bench to bedside.

Scientometric Analysis of Stem cell Research: A comparative study of India and other countries

The study explores the growth of Stem Cell research in India during 2001–2010. To compare Indian’s output of stem cell research several parameters like global publication share and rank, average citation per paper for 5 years block period, authorship pattern, collaborative Index, Collaborative Coefficient, Degree of Collaboration, etc. were studied. India is a member of SNAP and E7 countries. India is the member of both SNAP and E7 countries, are compared with top 10 countries of the stem cell research productivity. The Web of Knowledge database has been used for collecting the data of stem cell research for the study period of 10 years. (2001–2010).

Stem cell innovation system in India: Emerging scenario and future challenges

The present paper is an attempt to explore the emerging stem cell innovation system in India. It is contended that the social capital in terms of linkages of various sorts can no longer be ignored to strengthen the innovation system and that the coevolution of technology and institutions is yet to emerge. It seems that given the nature of complex technologies involved, there is a greater need felt for R&D and training collaboration and hence linkages of various types are taking place. For shaping futures for a balanced growth of this sector, the institutions in India will have to be geared towards greater coordination, promotion of greater knowledge flows at national as well international levels. This paper also analyses the strengths and barriers in the development of rapidly growing stem cell research in India along with future challenges.

Advancements in stem cell research: an Indian perspective-II

Stem cell research has stolen the limelight in the past decade and created a lot of hype and hope. Notwithstanding all the hype, development in stem cells have come a long way. Stem cell research in India is at par with the developed nations in the global arena. doi : 10.5214/ans.0972.7531.1017303

Advancements in stem cell research : an Indian perspective-ll.

Stem cell research has stolen the limelight in the past decade and created a lot of hype and hope. Notwithstanding all the hype, development in stem cells have come a long way. Stem cell research in India is at par with the developed nations in the global arena.

The Bioethical Vacuum: National Policies on Human Embryonic Stem Cell Research in India and China

AbstractDeveloping countries have sought to profit from theSecondly, we discuss government policies on the institutional aspects of hESR that have made China relatively attractive to foreign investors compared to India. In the concluding part, we discuss various dimensions of bioethics with regards to hESR, and how governing bodies mobilise cultural resources as economic capital.

STEM CELL RESEARCH IN INDIA — A GROWING CLINICAL OPPORTUNITY

The article is a brief summary of the stem cell research in India.