In this paper, a strengthened T-shaped concrete-filled steel tubular (CFST) column-steel beam joint is proposed. The joint is strengthened in the core region of the column wall as well as the beam, to avoid buckling of the column wall and outward displacement of the plastic hinge at the beam end. To study the damage modes and seismic performance of the joint, low-cycle loading experiments on two full-scale specimens of the joint were carried out. The results show that each specimen was damaged by plastic hinging of the steel beam flanges, the column walls did not buckle, and all had a good seismic performance. In addition, Abaqus finite element software was utilized to optimize the joints by analyzing the effects of changing the dimensions of the strengthened column and modifying the structure of the beam-column connection. Simulation results show that increasing the thickness and height of the strengthened column wall enhances the joint's load capacity, stiffness, and energy dissipation. it is recommended that the width-to-thickness ratio of the strengthened columns should be at most 0.08 and the beam-to-column height ratio should be kept at least 1.3. Additionally, two optimization methods, reducing the wall thickness of the steel corbel and weakening the steel beam flange, can effectively reduce weld tearing at the beam-to-column connections, while guaranteeing a good seismic performance. It is suggested that the slope of the steel corbel is not less than 1:6.25, and the weakening ratio of the steel beam flange is not greater than 0.267.