We investigate the non-linear system of ordinary differential equationsu′(t)=f(t,u(t)),a.e.t∈[a,b],subject to the state-dependent impulse conditionu(t+)−u(t−)=γ(u(t−))fort∈(a,b)suchthatg(t,u(t−))=0and the linear two-point boundary conditionAu(a)+Cu(b)=d.Here, −∞<a<b<∞,f and γ are given continuous vector-functions, g is a continuous scalar function, A, C are constant matrices, and d is a constant vector. The instants of time t where the jump occurs are determined by the equation g(t,u(t−))=0 and, thus, are unknown a priori and essentially depend on the solution u. We discuss a reduction technique allowing one to combine the analysis of existence of solutions with an efficient construction of approximate solutions. At present, according to the authors’ knowledge, no numerical results for boundary value problems with state-dependent impulses are available in the literature.