To examine the biomedical signals from the human body is of a challenging task. Signal acquisition of the biosignal needs proper design methodology with the estimation of consequences further. In this paper we discuss about the signal acquisition of EoG using the surface electrodes and to amplify the weak biopotential signal an amplifier is proposed with the additive noise reduction filter. The biopotential instrumentation amplifier is designed using standard operational amplifier that posses the high voltage swing. However the major artifacts present in the EoG signal acquisition is because of power line interference can be eliminated by notch filter.
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