Standard MUMPS Research Articles

Towards a better understanding of the CMUTs potential for SHM applications

The ability of capacitive micromachined ultrasonic transducer (CMUTs) to design broadband sensors for structural health monitoring (SHM) is studied through both multi-frequency and bandwidth aspects. Elementary cells are composed of circular membranes fabricated using the standard MUMPS Process. The multi-frequency aspect, which involves different individual membranes from 50 to 250 μm radius, is theoretically addressed through a numerical modeling. The targeted frequency range, consistent with the SHM application, is then between 80 kHz and 2 MHz. Geometrical features induced by the manufacturing process greatly affect the dynamic properties of the membranes and this is experimentally validated. The bandwidth aspect is also addressed on an array of identical 100 μm radius membranes thus involving their intrinsic capabilities. Harmonic excitation with targeted frequencies 300, 530 and 800 kHz, below and beyond the resonance frequency of the membranes, are performed. The influence of the bias voltage VDC on the signal-to-noise ratio is studied according to the excitation frequency. As a result, a signal-to-noise of 20 dB is achieved around the resonance frequency. Finally, the circular membranes array is tested for acoustic emission sensing through a pencil lead break test. In spite of a low signal-to-noise ratio, acoustic events are clearly detected. The multi-frequency aspect and the large bandwidth capability of the CMUTs are hence demonstrated and highlight the adaptability of the sensor to its environment.

Anti-mumps virus activity by extracts of Mimosa pudica, a unique Indian medicinal plant

Mumps is an acute and self-limiting disease characterized by parotitis, however in some cases it leads to aseptic meningitis, deafness, encephalitis and orchitis, which is a serious health concern. MMR vaccination was successful in eradicating the disease however, recent reports question the efficacy of MMR vaccine and countless outbreaks are observed in vaccinated populations throughout the world. Lack of specific treatment methods for mumps infection and inefficiency of MMR vaccine in vaccinated populations accentuates the need for the development of novel drugs to control mumps virus mediated serious infections. It was with this backdrop of information that the anti-mumps virus activity of Mimosa pudica was evaluated. Suspected mumps cases were collected to isolate a standard mumps virus by systematic laboratory testing which included IgM antibody assays, virus isolation, RT-PCR and phylogenetic analysis. The virus was quantified by TCID50 assay and anti-mumps virus property was evaluated by CPE reduction assay and cytotoxicity of the extract was measured by MTT assay and phytochemical analysis was done by gas chromatography-mass spectroscopy. The RT-PCR and phylogenetic tree analysis of the SH gene sequence of the clinical isolate showed it to be mumps virus genotype C. 150μg/ml concentration of M. pudica completely inhibited mumps virus and the drug was found to be non-toxic up to 2mg/ml. M. pudica was thus found to be a potent inhibitor of MuV.

Chemometric comparison of polychlorinated biphenyl residues and toxicologically active polychlorinated biphenyl congeners in the eggs of Forster's Terns (Sterna fosteri)

The separation and characterization of complex mixtures of polychlorinated biphenyls (PCBs) is approached from the perspective of a problem in chemometrics. A technique for quantitative determination of PCB congeners is described as well as an enrichment technique designed to isolate only those congener residues which induce mixed aryl hydrocarbon hydroxylase enzyme activity. A congener-specific procedure is utilized for the determination of PCBs in whichn-alkyl trichloroacetates are used as retention index marker compounds. Retention indices are reproducible in the range of ±0.05 to ±0.7 depending on the specific congener. A laboratory data base system developed to aid in the editing and quantitation of data generated from capillary gas chromatography was employed to quantitate chromatographic data. Data base management was provided by computer programs written in VAX-DSM (Digital Standard MUMPS) for the VAX-DEC (Digital Equipment Corp.) family of computers.

VAMPP: a veterinary automated management and production control program for swine breeding farms. I. Main features.

To improve the herd health and production management on swine breeding farms the Department of Herd Health and Ambulatory Clinic (University of Utrecht) developed a computer package. The basic package includes action lists, physical performance reports, analysis and economic programs. During the development of the software package it was emphasised that the programs should be user friendly (easy to handle, with no special codes), and should have an enormous flexibility to guarantee easy updating and a long life for the whole package. The Standard MUMPS system, which offers a unique data base structure and access method, was thus employed. The software runs on a central mini-computer with telephone lines for farmers and veterinary surgeons. In addition, the 'post-in post-out' method can be used; a micro-computer version of the package also is available.

An Integrated Perinatal Information System and Telecommunications Networking

The integrated perinatal information system in Albany Medical Center has two significant features: that of a flexible user-definable database and ease of networking both locally and regionally. The unified perinatal record is structured in Ansi standard MUMPS and resides on the College Vax 750. A special set of program tools ensures effective multi-split screen display, moving pointers, and corresponding multiple choice entries. Because it is self contained, it has the ability to create complex data structures without programming. A powerful math/statistical library has been incorporated. In house, the use of existing PABX wire allows for simultaneous voice/data traffic. Linkage to the regional system is made by modem connection. The system is compatible with the demands of both clinical and regional management.

Microcomputer translator for medical text: Theorem verification for chapter two of Zeman's modal logic

The increasing availability of computer readable documents and advances in computing power have created a renewed interest in computer translators. This paper describes the TRANSOFT medical document translator, a table-driven system written in American National Standard MUMPS, which handles a variety of translation problems. As one test of the TRANSOFT system, we submitted all theorems from Chapter Two of Zeman's Modal Logic to verification by Gentzen reduction and the Quine-McCluskey algorithm. Three apparent typographical errors were detected, but the translator otherwise confirmed the 179 theorems in this chapter. The TRANSOFT translator has the advantages of user control of the lexicon and grammar and sufficient conditions to prevent indefinite cycling of the program.

LAMP. A data management and analysis system for patient registries and clinical studies.

A computer system for the management and analysis of clinical data is described. The system is implemented in the ANSI standard MUMPS language and runs on popular minicomputers. The system is designed to allow clinical investigators or research assistants to define a data base, enter and edit data, produce patient-specific reports, and perform a variety of analyses on user-specified groups of subjects. Programmer intervention is not required at any stage of the management or analysis process, and on-line documentation provides a friendly environment for inexperienced users.

Data Base Management System For Tracking Occupational Health

An Occupational Health Information System (OHIS), a data base management system for tracking occupational health, has been developed. A primary feature is its ability to correlate employee workplace environment with health. Hardware implementation of OHIS is on a minicomputer with application programs written in ANSI standard MUMPS language. OHIS integrates personnel, medical and industrial hygiene/toxicology information into one data base. The personnel module is comprised of demographic information collected and updated by the personnel department. The medical module utilizes an interactive video display terminal (VDT)-driven questionnaire and multiphasic testing subsystems which are accessed selectively by authorized users. The backbone of OHIS is a parameter dictionary of all possible data elements. A final medical report includes a medical history summary, physical findings and X-ray interpretation, highlighted and normal test findings, computer interpretations, and a final one-page summary of problem and health-risk information. Information characterizing the workplace environment is captured and reported by the questionnaire subsystem. This questionnaire is designed to define: 1) monitoring conditions, 2) sample analysis, 3) measurement results, and 4) personal protective equipment used. These data provide a means of assigning environmental exposure measurements to appropriate employees.

Mumps virus-persistently infected cell cultures release defective interfering virus particles.

Summary Two human cell cultures, HEp-2 and L-41, persistently infected with mumps virus, produced small amounts of slowly replicating small-plaque infectious virus and detectable amounts of defective interfering virus particles which were similar to standard mumps virus in polypeptide composition, contained subgenomic size RNAs and interfered with standard mumps virus replication in susceptible cells.

Design of a MUMPS interpreter

AbstractThis paper describes the basic design of Comp Consultants Standards Mumps system for Tano Corporation's Outpost 11 6800 based micro computer running under the Flex 2.0 floppy disk operating system with 64K bytes of random access memory. The Mumps system consists of an executive which includes I/O device handlers, and interpreter for Standard Mumps and a floppy disk storage system for global variables based on balanced trees with key compression by indexes and with 32 K of random access memory buffers to make up for the slow floppy disk access times.Comp Consultants Mumps involves some significant departures from previous Mumps implementations. In particular local variables and routine lines are stored in the same manner as global variables. For example the storage key for a routine consists of three parts: The routine name, a label, and a line offset number. Representing local variables and routines as global variables not only increases the available buffer space by eliminating special code to handle local variable storage, routine storage, and program editing; but also increases the utilization of the buffers by keeping in memory what is most often accessed regardless whether it is a local variable, a global variable, or program code. This unified representation of local variables and routines as global variables is described in detail in this paper.

MEDUS/A

MEDUS/A was designed by members of the Health Systems Project at the Harvard School of Public Health. As a general-purpose DBMS, it enables clinical and public health researchers and their staff to define a database and enter, query, and retrieve their data for analysis without a programmer. The system has simultaneously supported a variety of projects in the Harvard Medical Area since 1976 and is ready for release outside of Harvard in a new version written in Standard MUMPS. Though designed for medicine, the system is sufficiently general for other fields.

MARS — Its Tenth Anniversary of Operation and its Future

The Missouri Automated Radiology System recently passed its tenth year of clinical operation at the University of Missouri. This article presents the views of a radiologist who has been instrumental in the conceptual development and administrative support of MARS for most of this period, an economist who evaluated MARS from 1972 to 1974 as part of her doctoral dissertation, and a computer scientist who has worked for two years in the development of a Standard MUMPS version of MARS. The first section provides a historical perspective. The second deals with economic considerations of the present MARS system, and suggests those improvements which offer the greatest economic benefits. The final section discusses the new approaches employed in the latest version of MARS, as well as areas for further application in the overall radiology and hospital environment. A complete bibliography on MARS is provided for further reading.

MARS — Its Tenth Anniversary of Operation and its Future

The Missouri Automated Radiology System recently passed its tenth year of clinical operation at the University of Missouri. This article presents the views of a radiologist who has been instrumental in the conceptual development and administrative support of MARS for most of this period, an economist who evaluated MARS from 1972 to 1974 as part of her doctoral dissertation, and a computer scientist who has worked for two years in the development of a Standard MUMPS version of MARS. The first section provides a historical perspective. The second deals with economic considerations of the present MARS system, and suggests those improvements which offer the greatest economic benefits. The final section discusses the new approaches employed in the latest version of MARS, as well as areas for further application in the overall radiology and hospital environment. A complete bibliography on MARS is provided for further reading.

Use of an Interactive Teaching Program to teach Medical Workers about Mumps Programming

The MUMPS computer language is widely and increasingly used for medical applications. It is useful for medical students and others in the medical environment to have an understanding of such languages that can help them perform their jobs well. The author is therefore making available an interactive teaching program to instruct such people in the MUMPS computer language. Use of the teaching program is reported for 19 novice MUMPS programmers and compared with results for two experienced programmers. Free-text comments by the novices emphasize areas in which they had difficulty. There is a considerable variation in the mean time taken by the novices to answer the questions, and in the number of questions repeated because of erroneous answers. Most novices found the teaching program very helpful. A copy of the Standard MUMPS teaching program and the QUEST driver on which it is based has been sent to 24 institutions, including six in Europe and one in Japan, for further use.

MUMPS implementations on microprocessors.

Microprocessors are becoming increasingly important in the solution of many problems within the medical information field. They are suitable for use in controlling such processes as data entry and verification, stand-alone Computer Assisted Instruction, generation and testing of basic code, and as entry points to larger communication networks with shared data-bases. Because of their potential and versatility, it is desirable to implement on these microprocessors the same language that is to be used on larger members of a full scale medical information system. MUMPS is ideally suited to this environment, having been designed in such a way that it can be run on microprocessors without degradation of its string handling and file management characteristics.Our implementation approach was to adopt a machine-independent technique, using the Transition Diagram Language in which Standard MUMPS has been defined. A high level (ALGOL) driver was written for the Tdl, in which the initial output was assembly code for ...