The article is devoted to the study of theoretical and methodological aspects of the formation and development of pharmaceutical legal relations in Ukraine in modern conditions of the development of the social state and modernization of legal regulation of the pharmaceutical sphere. It is argued that the global pandemic of the coronavirus COVID-19 actualizes and objectifies the need to improve the legal regulation of the pharmaceutical sphere both at the international legal and domestic levels in order to ensure the most effective implementation of mechanisms to overcome this global threat. The study of theoretical and methodological aspects of the formation and development of pharmaceutical relations in Ukraine is important and timely, given the current processes of modernization of the social sphere and the need to improve existing legislation on drug circulation, which requires the development of appropriate conceptual principles and paradigms of pharmaceutical law relevant regulations. It is noted that pharmaceutical legal relations can be defined as a set of administrative-legal and economic-legal relations, which, due to their complex legal content, have a double public-private nature, arising between public authorities, business entities and natural persons – consumers regarding the development, expertise , state registration, standardization, quality control and safety of production (manufacturing), storage, transportation, marketing and advertising, circulation, distribution, appointment, dispensing, use and disposal of pharmaceutical products – medicines, as well as regulation of the legal status of intellectual property in the field pharmaceuticals and the rights to them.