Stand-alone Process Research Articles

Comprehensive evaluation of various CO2 capture technologies through rigorous simulation: Economic, equipment footprint, and environmental analysis

The comprehensive evaluation of various CO2 capture technologies from multiple perspectives remains limited, yet it is crucial for the successful implementation and deployment of carbon capture solutions to achieve carbon neutrality. This study presents a framework for assessing representative CO2 capture processes from key point sources through rigorous simulation. Eight scenarios were developed and compared, comprising four standalone processes (i.e., physical absorption (PHYABS), chemical absorption (CHEABS), dual-reflux pressure swing adsorption (DRPSA) and pressure-temperature swing adsorption (PTSA)) and four hybrid processes that integrate different adsorption and absorption processes. To evaluate each scenario, an integrated indicator, the Economics, Equipment footprint, and Environmental Score (EEES), was introduced. Our results indicate that the standalone CHEABS exhibits the lowest EEES of 0.120, highlighting its technological readiness and superiority over other processes. In contrast, the standalone PHYABS (EEES=0.168) and the hybrid PHYABS/PTSA process (EEES=0.242) emerge as viable alternatives, balancing environmental performance with economic and spatial considerations. Standalone PTSA (EEES=0.465) and DRPSA (EEES=0.706) are less favorable because of their higher utility demands and larger equipment footprints. Similarly, hybrid processes, namely, DRPSA/CHEABS (EEES=0.891), CHEABS/PTSA (EEES=0.837), and DRPSA/PHYABS (EEES=0.784), are less advantageous across all three metrics. Furthermore, sensitivity analyses indicated that carbon permit prices exert a negligible effect on the process economics. Additionally, it appears that government subsidies may play a crucial role in facilitating the development of CO2 capture technologies within the industrial sector. Overall, this study provides a robust framework for evaluating CO2 capture processes and offers practical recommendations for technology deployment.

Enhancing textile wastewater treatment for subsequent biological processes by integrating electrooxidation and electrocoagulation

ABSTRACT The presence of refractory contaminants in textile wastewater is one of the major concerns while handling them with the biological processes at common effluent treatment. Electro-oxidation (EO) as a standalone process is an insufficient treatment method for the abolition of inorganic contaminants (carbon and non-carbon). By incorporating electrocoagulation (EC) as an associated treatment method after EO, removal of such contaminants becomes easy, which not only makes the treated wastewater fit for biological remediation but also reduces load on biological units. The removal of non-carbonic impurities was assessed in terms of improvement in the chemical oxygen demand (COD) post EC. L25 orthogonal array of experiments was obtained using the Taguchi method. From the S/N ratio plot, the optimal process combination was obtained as, EO with current density = 25 mA/cm2, electrolysis time = 50 min followed by EC with current density = 18 mA/cm2, speed of rotation = 50 rpm and electrolysis time = 40 min. The enhancement in COD and total organic carbon removal efficiencies after EC were 65.11 and 63.57%, respectively, over EO. The biodegradability index also improved from an initial value of 0.098–0.737 post-hybrid treatment. Inorganic carbon reduced from a value of 36.37 mg/L after EO to 0.1 mg/L post EC.

Feasibility study on hybrid manufacturing – combining laser‐based powder‐bed fusion and chill casting on the example of EN AC‐42000 alloy

AbstractLaser‐based powder‐bed fusion can be combined with casting into a hybrid manufacturing process. This is done to simultaneously utilize advantages of both processes. To examine related challenges stemming from this combination when using aluminium alloys, first experiments were conducted with EN AC‐42000 alloy, an alloy common in both standalone processes. EN AC‐42000 alloy samples with different surface treatments were placed into a sand mould and cast on to with an aluminium melt. The contact region between the partially molten insert and the cast material was examined with light microscopy. The main challenges were shown to be comprised of bonding issues due to present oxides and a high porosity. The high porosity was traced back to a porosity increase in the laser‐based powder‐bed fusion insert.

Multiparameter Sensing of Oxygen and pH at Biological Interfaces via Hyperspectral Imaging of Luminescent Sensor Nanoparticles.

Chemical dynamics in biological samples are seldom stand-alone processes but represent the outcome of complicated cascades of interlinked reaction chains. In order to understand these processes and how they correlate, it is important to monitor several parameters simultaneously at high spatial and temporal resolution. Hyperspectral imaging is a promising tool for this, as it provides broad-range spectral information in each pixel, enabling the use of multiple luminescent indicator dyes, while simultaneously providing information on sample structures and optical properties. In this study, we first characterized pH- and O2-sensitive indicator dyes incorporated in different polymer matrices as optical sensor nanoparticles to provide a library for (hyperspectral) chemical imaging. We then demonstrate the successful combination of a pH-sensitive indicator dye (HPTS(DHA)3), an O2-sensitive indicator dye (PtTPTBPF), and two reference dyes (perylene and TFPP), incorporated in polymer nanoparticles for multiparameter chemical imaging of complex natural samples such as green algal biofilms (Chlorella sorokiniana) and seagrass leaves (Zostera marina) with high background fluorescence. We discuss the system-specific challenges and limitations of our approach and further optimization possibilities. Our study illustrates how multiparameter chemical imaging with hyperspectral read-out can now be applied on natural samples, enabling the alignment of several chemical parameters to sample structures.

Combination of CO2 electrochemical reduction and biomass gasification for producing methanol: A techno-economic assessment

Combining CO2 electrochemical reduction (CO2R) and biomass gasification for producing methanol (CH3OH) is a promising option to increase the carbon efficiency, reduce total production cost (TPC), and realize the utilization of byproducts of CO2R system, but its viability has not been studied. In this work, systematic techno-economic assessments for the processes that combined CO2R to produce CO/syngas/CH3OH with biomass gasification were conducted and compared to stand-alone biomass gasification and CO2R processes, to identify the benefits and analyze the commercialization potential of different pathways under current and future conditions. The results demonstrated that the process that combined biomass gasification with CO2R to CO represents a viable pathway with a competitive TPC of 0.39 €/kg-CH3OH under the current condition. For all the combined cases, electricity usage for CO2R accounts for 36–76% of total operating cost, which plays a key role for TPC. Sensitivity analysis confirmed that the process that combined biomass gasification with CO2R to CO is sensitive to the price of electricity, while both CO2R performance and prices of stack and electricity are important for the processes that combined with CO2R to syngas/CH3OH.

Design of an integrated system for electrofuels production through Fischer-tropsch process

There has been a growing recognition in recent years that Electrofuels (e-fuels), also known as renewable and sustainable fuels, which are produced from hydrogen and carbon dioxide as the primary feedstocks, have great potential to reduce carbon footprint and address climate change. In the present study, contrary to most previous studies in which the sources of feedstock's preparation were considered as block boxes, two stand-alone processes are taken into account and incorporated into the e-fuels production system. H2 is obtained by a high-temperature electrolysis system having an overall efficiency nearly twice that of a low-temperature electrolysis system. CO2 is captured from a power plant flue gas stream with a purity of 99.81%. Investigating heat integration potential in such an integrated plant is an up-to-date and interesting topic and has not yet been well explored. Therefore, a heat integration within the three individual processes is implemented to reduce energy consumption. The design of the process-to-process heat transfer section is carried out using pinch design rules. By integrating individual units, approximately 42% of the required cold utility, traditionally supplied by chilled water and refrigerants, is allocated to generate high and medium-pressure steams. Having used the high-temperature steam electrolysis for H2 production, a process that requires less external electricity compared to low-temperature water electrolysis, a power-to-liquid efficiency of 70% is achieved. Furthermore, the results reveal a carbon conversion ratio of 98.6%, indicating the effective converting the carbon from the feedstock into liquid hydrocarbons.

Assessment and comparison of thermochemical pathways for the rice residues valorization: pyrolysis and gasification.

Lignocellulosic biomass conversion applying thermochemical routes has been postulated as an alternative for generating renewable energy. This research compares energy-driven biorefineries based on two thermochemical routes addressed to upgrade rice husk and rice straw produced in the Department of Sucre-Colombia. Initially, this research analyzes the physico-chemical and structural characterization of the rice residues. Four different scenarios were proposed to compare the energy-driven biorefineries based on fast pyrolysis and gasification considering technical, economic, and environmental metrics. These biorefineries were simulated using the Aspen Plus V.14.0 software. The novelty of this research is focused on the identification of the biorefinery with the best techno-economic, energetic, and environmental performance in the Colombian context. Economic and environmental analyses were done by using economic metrics and emissions. From an economic perspective, the stand-alone gasification process did not have a positive economic margin. In contrast, the fast pyrolysis process has the best economic performance since this process has a positive profit margin. Indeed, scenario 1 (fast pyrolysis of both rice residues) presented an economic margin of 13.75% and emissions of 2170.92 kgCO2eq/kg for 10years. However, this scenario was not energetically the best, holding second place due to the feedstock requirements, compared to gasification. The biorefinery scenario 1 has the best performance.

Ohmic cooking of carrots: Limitations in the use of power input and cooking value for process characterization

Ohmic cooking is considered a fast and homogeneous process. However, achieving heating uniformity depends on several process parameters and intrinsic product characteristics. Furthermore, reference indicators for evaluating the ohmic process and generating reliable comparisons with conventional cooking are still lacking. The objective of this study was to investigate the reliability of the use of power input and cooking value as process indicators. The results showed that the specific ohmic power did affect only the heating rate but not the heating uniformity and the tissue softening rate. Therefore, the power input as process acceleration tool is not sufficient as stand-alone process indicator because other critical parameters (i.e., electrical conductivity) need to be taken into account to display the complex product-process-interactions. The cooking value was proven to be not valid as indicator for ohmic heating, as it does not take into account additional effects not attributable to only thermal exposure.

Prefeasibility analysis of biomass gasification and electrolysis for hydrogen production

Hydrogen is a key energy vector to accomplishing energy transition and decarbonization goals proposed in the transport and industrial sectors worldwide. In recent years, research has focused on analyzing, designing, and optimizing hydrogen production, searching to improve economic prefeasibility with minimal emissions of polluting gases. Therefore, the techno-economic analysis of hydrogen production by electrolytic and gasification processes becomes relevant since these processes could compete commercially with industrial technologies such as SMR - Steam methane reforming. This work aims to analyze hydrogen production in stand-alone processes and energy-driven biorefineries. The gasification and electrolysis technologies were evaluated experimentally, and the yields obtained were input data for scaling up the processes through simulation tools. Biomass gasification is more cost-effective than electrolytic schemes since the hydrogen production costs were 4.57 USD/kg and 8.30 USD/kg at an annual production rate of 491.6 tons and 38.96 tons, respectively. Instead, the electrolysis process feasibility is strongly influenced by the recycled water rate and the electricity cost. A sensitivity analysis was performed to evaluate the temperature, pressure, and current density variability on the hydrogen production rate. The increase in pressure and current density induces parasitic currents while the temperature increases hydrogen production. Although higher hydrogen production rates from gasification, the syngas composition decreases the possibility of being implemented in applications where purity is critical.

Exploring Exergy Performance in Tetrahydrofuran/Water and Acetone/Chloroform Separations

Distillation is significantly influenced by energy costs, prompting a need to explore effective strategies for reducing energy consumption. Among these, heat integration is a key approach, but evaluating its efficiency is paramount. Therefore, this study presents exergy as an energy quality indicator, analyzing irreversibility and efficiencies in tetrahydrofuran/water and acetone/chloroform distillations. Both systems have equimolar feed streams, yielding products with 99.99 mol% purity. The simulations are performed using Aspen Plus™, enabling evaluation at the column level, as a standalone process, or from a lean perspective that considers integration opportunities with other plants. The results show that, despite anticipated energy savings from heat integration, economic viability depends on pressure sensitivity. The results demonstrate that heat-integrated extractive distillation for acetone/chloroform raises utility energy consumption. Exergy calculations comparing standalone and total site integration reveal the variation in distillation efficiency with operation mode. Global exergy efficiency in both extractive and pressure-swing distillation depends on the fate of condenser duty. In heat-integrated extractive distillation, global exergy efficiency drops from 8.7% to 5.7% for tetrahydrofuran/water and 11.5% to 8.3% for acetone/chloroform. Similarly, heat-integrated pressure-swing distillation sees global exergy efficiency decrease from 34.2% to 23.7% for tetrahydrofuran/water and 9.5% to 3.6% for acetone/chloroform, underscoring the nuanced impact of heat integration, urging careful process design consideration.

Techno-economic assessment of integrated NH3-power co-production with CCS and energy storage in an LNG regasification terminal

Energy efficiency and carbon capture and storage (CCS) are two key levers to attain global warming targets. Integration of various industrial and energy processes as well as complementary use of fuels with low carbon intensity such as natural gas with renewable sources will enable to mitigate environmental impacts in a cost competitive manner. This study proposes one such opportunity through integration of LNG cold exergy utilization for liquid N2 energy storage during regasification coupled to a novel NH3-electricity co-production scheme with CCS. A techno-economic benchmarking between standalone NH3 production process with net electricity imports (Case A), an integrated co-production solution (Case B) and non-integrated co-production plant with a standard combined cycle for power generation (Case C) is performed. Base economic assumptions are a natural gas price of 6.5 €/ton, CO2 tax of 100 €/ton, NH3 selling price of 400 €/ton and electricity average price of 80 €/MWh. At varying power generation capacity factors CFEl ranging from 30 to 50%, the electricity price premium required by the co-production schemes to break even with Case A is 2.5–9.9 €/MWh lower for Case B compared to Case C, with a premium as low as 12.9 €/MWh at 50% CFEl for the former when 2 days' worth of energy storage capacity is constructed. Thus, integration improves economic competitiveness for short storage times, applicable to regions with reliable year-round solar resources. However, the competitive advantage disappears when storage periods longer than one week are considered, such as power systems with high wind shares or seasonal solar availability.

Integration of electrochemical processes in a treatment system for landfill leachates based on a membrane bioreactor

The use of electrocoagulation (EC) and anodic oxidation (AO) processes was studied for improving a treatment system for landfill leachates based on a membrane bioreactor (MBR) and a nanofiltration step. The main limitation of the current full-scale system is related to the partial removal of organic compounds that leads to operation of the nanofiltration unit with a highly concentrated feed solution. Application of the EC before the MBR participated in partial removal of the organic load (40 %) with limited energy consumption (2.8 kWh m−3) but with additional production of iron hydroxide sludge. Only AO allowed for non-selective removal of organic compounds. As a standalone process, AO would require a sharp increase of the energy consumption (116 kWh for 81 % removal of total organic carbon). But using lower electric charge and combining AO with EC and MBR processes would allow for achieving high overall removal yields with limited energy consumption. For example, the overall removal yield of total organic carbon was 65 % by application of AO after EC, with an energy consumption of 21 kWh m−3. Results also showed that such treatment strategy might allow for a significant increase of the biodegradability of the effluent before treatment by the MBR. The MBR might then be dedicated to the removal of the residual organic load as well as to the removal of the nitrogen load. The data obtained in this study also showed that the lower electric charge required for integrating AO in a coupled process would allow for strongly decreasing the formation of undesired by-products such as ClO3− and ClO4−.

Adsorption on activated carbon combined with ozonation for the removal of contaminants of emerging concern in drinking water

The presence of Contaminants of Emerging Concern (CECs) in drinking water is raising concern for potential negative effects on human health. Ozonation and adsorption on activated carbon are the most suitable processes for CECs removal in drinking water treatment plants (DWTPs). This study aims at evaluating the performance of ozonation and adsorption as in-series processes compared to those of the stand-alone processes, focusing on 18 compounds representative of various CECs families. No CECs spike was performed to evaluate the effectiveness of these processes towards CECs at their environmental concentrations. Adsorption isotherms were performed on water samples collected before and after the full-scale ozonation in a DWTP, testing different combinations of ozone and activated carbon doses. Generally, the combination of the two processes was beneficial (83% average removal) compared to adsorption and ozonation alone (71% and 34% average removal respectively). The effect of ozonation on adsorption depends on CECs reactivity with ozone, since ozonation improves the adsorption performance of poorly-oxidizable CECs, but worsens that of well-oxidizable compounds. The removal of organic matter, investigated by absorbance at 254 nm and fluorescence, by ozonation reduces competition for the subsequent CECs removal by adsorption (up to 20% increase of total CECs adsorption). Finally, the removal of both absorbance and fluorescence seems to be a good proxy variables for total CECs adsorption, with different relationships depending on the presence of ozonation. Conversely, it is not effective for ozonation, since the relationship depends on the reactivity of the specific CEC with ozone.

Utilization of Response Surface Methodology in Electrocoagulation for Process Optimization and Parametric Analysis

AbstractElectrocoagulation (EC) is a well‐recognized and feasible treatment technique for wastewater treatment. The process optimization and analysis of process parameters of EC not only aid to scale up the EC process at an industrial level but also help to explore the economic and environmental considerations to achieve higher efficiency. Response surface methodology (RSM) is a prominent chemometric approach for both process optimization and evaluation of different factors for the removal of target pollutants from wastewater. This review provides a thorough examination of notable scholarly works that focus on the use of the RSM in EC for the purpose of wastewater treatment. Furthermore, the current advancements in implementing the RSM approach not only for standalone EC processes but also for the case are described where it is being practiced as a part in the integrating system for wastewater treatment.

Alternative Integrated Ethanol, Urea, and Acetic Acid Processing Routes Employing CCU: A Prospective Study through a Life Cycle Perspective

Despite the importance of inputs such as urea, ethanol, and acetic acid for the global production of food, energy, and chemical bases, manufacturing these substances depends on non-renewable resources, generating significant environmental impacts. One alternative to reducing these effects is to integrate production processes. This study compares the cumulative environmental performance of individual production routes for ethanol, urea, and acetic acid with that of an integrated complex designed based on Industrial Ecology precepts. Life Cycle Assessment was used as a metric for the impact categories of Global Warming Potential (GWP) and Primary Energy Demand (PED). The comparison occurred between the reference scenario, which considers individual processes, and six alternative integrated arrangements that vary in the treatment given to a stream concentrated in fuels generated in the Carbon Capture and Usage system that serves the processing of acetic acid. The study showed that process integration is recommended in terms of PED, whose contributions were reduced by 46–63% compared to stand-alone processes. The impacts of GWP are associated with treating the fuel stream. If it is treated as a co-product and environmental loads are allocated in terms of energy content, gains of up to 44% can be expected. On the other hand, if the stream is a waste, the complex’s GWP becomes more aggressive than the baseline scenario by 66%.

Industrial production of green diesel in Brazil: Process simulation and economic perspectives

The purpose of this work is to apply process simulation to infer the technical and economic bottlenecks of the industrial production of green diesel, taking as a context the Brazilian market at the end of 2021/beginning of 2022. In the considered economic scenario, a stand-alone green diesel production process does not seem economically viable in Brazil, as the fuel would need to cost 30 % more than the European market price and twice the conventional diesel price (US$ 2.08/L) to compensate for the investment made. However, significant price reductions - 10 %–15 % in the considered scenarios (to US$ 1.76–1.87/L) - can be achieved with capital and energy savings due to the availability of a conventional refinery hydrotreatment unit, and eventual parity with market prices can be achieved with soybean oil price reductions (of 22–40 %, completely possible in the Brazilian market). This analysis shows that green diesel may be absolutely possible depending on the economic context and that there is room for its gradual incorporation in petroleum diesel. This is the first research article to demonstrate it though process simulation and to economically compare the investment on a stand-alone process with a refinery retrofit.

Zinc sulfate as a draw solute in forward osmosis and its regeneration by reagent precipitation

Forward osmosis (FO) is an emerging membrane technology that has gained huge interest for water treatment and reclamation, owing to its low energy consumption. Nevertheless, the lack of ideal draw solutions and efficient membranes hinder its large-scale applications. In this study, the potential of zinc sulfate draw solute to recover water from different brackish waters by FO was evaluated in terms of permeate water flux, reverse solute flux, and rate of water recovery. Product water having 9.8 and 360 ppm of total dissolved solids (TDS) was recovered from the diluted draw solution by employing a reagent precipitation (RP) and nanofiltration (NF) process, respectively. The draw solution was regenerated by adding a stoichiometric amount of sulfuric acid to the precipitates obtained in RP. In addition, the specific energy consumption (SEC) and water production cost for the water desalination using an FO-RP process were calculated and compared to the FO-NF and a stand-alone RO process. The SEC and water production cost for the FO-RP process were found to be about 0.5 kWh·m−3 and 0.09 $·m−3, respectively. Finally, it is suggested that zinc sulfate could be an excellent choice as a draw solute for water desalination by FO when coupled with reagent precipitation.

Design of experiments for micellar electrokinetic chromatography method development for the monitoring of water-soluble vitamins in cell culture medium.

Biopharmaceutical production takes place in complex processes which should be thoroughly understood. Therefore, the iConsensus project focuses on developing a monitoring platform integrating several process analytical technology tools for integrated, automated monitoring of the biopharmaceutical process. Water-soluble vitamin monitoring using (microchip) capillary electrophoresis (CE) is part of this platform. This work comprises the development of conventional CE methods as the first part towards integrated vitamin monitoring. The vitamins were divided based on their physical-chemical properties to develop two robust methods. Previously, a method for the analysis of cationic vitamins (pyridoxine, pyridoxal, pyridoxamine, thiamine and nicotinamide) in cell culture medium was developed. This work focused on the development of a micellar electrokinetic chromatography method for anionic and neutral vitamins (riboflavin, d-calcium pantothenate, biotin, folic acid, cyanocobalamin and ascorbic acid). By employing multivariate design of experiments, the background electrolyte (BGE) could be optimised within one experiment testing only 11 BGEs. The optimised BGE conditions were 200mM borate with 77mM sodium dodecyl sulphate at a pH of 8.6. Using this BGE, all above-mentioned cationic, anionic and neutral vitamins could be separated in clean samples. In cell culture medium, most anionic and neutral vitamins could be separated. Combining the two methods allows for analysis of cationic, anionic and neutral vitamins in cell culture medium samples. The next step towards integrated vitamin monitoring includes transfer to microchip CE. Due to the lack of fast and reliable methods for vitamin monitoring, the developed capillary methods could be valuable as stand-alone at-line process analytical technology solutions as well.

Analysis of integrated CO2 capture and utilization via calcium-looping in-situ dry reforming of methane and Fischer-Tropsch for synthetic fuels production

Calcium-looping is an attractive approach for removing CO2 in flue gas from the coal-fired power plant to form CaCO3. The integration of CO2 capture via calcium-looping and in-situ dry reforming of methane with CaCO3 allows the simultaneous CaCO3 decomposition to regenerate CaO and syngas production. The produced syngas is expected for further utilization, e.g. Fischer-Tropsch synthesis to produce valuable fuels. In this work, an integrated process of calcium-looping in-situ dry reforming of methane and Fischer-Tropsch was developed using Aspen Plus. Moreover, two other processes were also simulated as the comparison, consisting of the serial process of calcium-looping CO2 capture, ex-situ dry reforming of methane with CO2 and Fischer-Tropsch and the standalone process of calcium-looping CO2 capture. The results indicate that the reduction in the demand for CaO sorbent and the enhancement in Fischer-Tropsch products yield and carbon conversion efficiency are achieved by integrating in-situ dry reforming of methane with CaCO3. Additionally, integrating CO2 capture and in-situ dry reforming of methane with CaCO3 in the case of the integrated process is efficient for enhancing the system efficiency and energy availability. Compared with the serial process, the integrated process shows a drop in the heat energy requirement of 28.08% and possesses the energy conversion efficiency of 43.74% and exergy efficiency of 41.81%. This work exhibits the prospect of the integrated process of calcium-looping in-situ dry reforming of methane and Fischer-Tropsch in the field of CO2 capture and utilization for Fischer-Tropsch fuels production.

A strategy for commercialization of macroalga biorefineries

The transportation sector significantly contributes to global warming due to the extensive use of fossil fuels. Biofuels have the potential to eliminate inherent problems associated with the combustion of fossil fuels. However, large-scale deployment of biorefineries is limited because of high capital and operating costs as well as the low market value of biofuels that make such plants economically unfavorable. Additionally, using sustainable feedstock (algae, cyanobacteria, etc.), i.e., with no social, environmental, or technological challenges, is another major bottleneck for biorefineries. Considering these challenges, this study presents a strategy for the commercialization of macroalga-derived bioethanol via a circular economy-based integrated biorefinery concept. A standalone (conventional) process was designed for bioethanol production at 50.0 million gallons (189.3 million liters) per year capacity in Aspen Plus V12.2. Economic and environmental indicators were assessed through discounted cash flow and cradle-to-grave (SimaPro V9.4.0.7) analyses, respectively. Once the potential targets are identified, a novel integrated process was designed for biofuel and biochemical production, which is not only economically favorable in the current market but also has a better life cycle profile compared to that of a standalone process. The results showed that the integrated design has a minimum ethanol selling price of USD 0.35/L and a global warming potential of 0.35 kg CO2 eq/L of ethanol, which is 45% and 82.7% lower than that of the standalone design. Sensitivity analysis showed that the Bio-SA selling price, total capital investment, and seaweed price are the most critical economic parameters for the economic feasibility of the process.