Facial and cervical emphysema occurs as a result of air entering through the facial planes, a condition rarely seen in dental practice. In dentistry, compressed air is used to run the high-speed airotor drills and three-way air syringes. These two equipment are to be used with great precaution, especially when minor surgical procedures are done. It is highly recommended not to use these in major surgical procedures. Here, we present a case of spontaneous retropharyngeal emphysema, iatrogenically induced in a 64-year-old healthy patient undergoing root canal therapy on mandibular canines 33 and 43. Diagnosis has to be precise as this condition mimics allergic reactions and hematoma.