Spontaneous Blood Pressure Variability Research Articles

Analiza varijabilnosti arterijskog pritiska merenjem pritiska na obe ruke i u funkciji vremena u bolesnika sa de novo otkrivenom hipertenzijom

INTRODUCTION At the initial office visit, blood pressure should be measured in both arms, ideally with electronic devices that can measure them simultaneously. SBP difference between arms >10 mmHg must be confirmed by repeated measurements. If confirmed, the arm with the higher blood pressure should be used for all subsequent measurements, as its values more accurately reflect the level of blood pressure in the major arteries. Using blood pressure readings on the arm with higher pressure improves outcome prediction. A consistent difference in SBP between the arms >15 to 20 mmHg may be due to atherosclerosis and restriction of the large intrathoracic or supraclavicular arteries, necessitating investigation of arterial disease. The blood pressure values on the right and left brachialis arteries differ in most cases, and the higher one is taken as more accurate. Prognostic significance: for each 10 mmHg difference according to Agarwal (2008), the relative risk of total mortality increases by 24%. In order to accurately assess the degree of hypertension, the spontaneous variability of pressure as a function of time and the pressure difference between the arms must be taken into account. WORK OBJECTIVES: 1. Analysis of spontaneous blood pressure variability upon arrival and repeated after 5 to 30 minutes; 2. Blood pressure differences between the left (LR) and right arm (DR). MATERIALS AND METHODS: A prospective study was conducted from the database of the "Dr. Bastać" Internal Medicine Practice on 26 patients, average age 58±12 years, with newly discovered hypertension by measuring blood pressure with the indirect manometer method at the first examination immediately after arrival and after 15 minutes. The control group consists of 28 patients who do not have hypertension. The data were statistically processed with the Student's T test. WORK RESULTS The mean value (Xsr) of systolic and diastolic blood pressure (SKP/DKP) of the examined group on arrival is 166/92 mmHg on the right hand (DR), and 161/93 mmHg on the left hand (LR). and after rest at DR 153/90 mmHg and LR 149/87. There is a statistically highly significant difference especially between the CAP on the hands - it is always higher on the right hand by an average of 5 mmHg (p=0.002) and 4 mmHg after rest. Spontaneous variability was determined in 10 (40%) subjects where there was a statistically significant drop in tension after rest. After a 15-minute rest, the significance of pressure differences between arms is maintained, but the high variability of 40% post-rest pressure variability is lost. CONCLUSION: Pressure on arrival in newly diagnosed untreated patients is always higher on the right arm by an average of 5 mmHg (p=0.002), and after rest 4 mmHg, this difference is maintained. Spontaneous variability was determined in 10 (40%) subjects where there was a statistically significant drop in tension after rest. After 15 minutes of rest, the significance of the pressure differences between the arms is maintained, but the high pressure variability is lost.

The impact of spontaneous blood pressure variability on patient classification according to current hypertension guidelines

Annual Scientific Meeting of the British Hypertension Society. University of Strathclyde, Glasgow, Scotland 11–13 September 1995: PDF Only

Clinical value of blood pressure measurements: Focus on ambulatory blood pressures

Because clinic blood pressure values are compromised by 2 major limitations—the alerting reaction to clinic measurements and the spontaneous blood pressure variability—they have only a limited correlation with average 24-hour blood pressure values. Whether the latter should be employed routinely in substitution for, or in addition to, traditional blood pressure measurements has not yet been determined, however. To date, average 24-hour blood pressure values have been shown to correlate more closely than clinic blood pressure values with the organ damage of hypertension. A correlation with organ damage has been shown also for a number of blood pressure values within the 24 hours. Nevertheless, the clinical importance of 24-hour blood pressure and blood pressure variability has never been confirmed by prospective controlled studies. This information needs to be obtained before this approach is routinely employed in the clinical practice.

Continuous Ambulatory Blood Pressure Monitoring Versus Casual Blood Pressure in Borderline Hypertension

In 56 patients with borderline hypertension, casual blood pressure was compared with average daytime ambulatory blood pressure. The difference between these two values ranged from -20 to +40 mm Hg and was unrelated to spontaneous blood pressure variability, the blood pressure fall during sleep, and the peaks of pressure recorded during the day. Heart rate and a family history of hypertension were not predictive of the degree of difference between casual and average daytime recorder pressure. Target organ damage was present in 44% of the patients and was more closely correlated with recorder than with casual pressure.

Arterial baroreceptor control of blood pressure in man

Information on arterial baroreceptor control of circulation is much more restricted in man than in animals, largely because of the limitations in the techniques available in humans for this type of study. However, recent utilization of the neck chamber technique that addresses the primary function of an arterial baroreflex, i.e. blood pressure control, has provided a significant amount of information. This paper describes baroreceptor control of blood pressure as derived from neck chamber studies in normal people and discusses its modifications by exercise and ageing, and its participation in a phenomenon such as spontaneous blood pressure variability. The description given here is focused on aspects of this baroreceptor control that have changed the concept of the overall arterial baroreceptor function developed by means of techniques for studying only baroreceptor influences on heart rate.