Introduction: Allogeneic Stem Cell Transplantation (ASCT) and, consequently, the chronicity associated with this life event have a growing prevalence and a significant impact on the life and daily life of each person who experiences it. It is necessary to reflect on the care needs of this group of vulnerable people. Comfort is a concern, and its improvement is a desired outcome of healthcare. To achieve this, it is necessary to know the needs of the people who are the focus of care. Aim: This paper aims to understand the needs of comfort care in the lived experience of comfort for survivors of ASCT. Methodology: Qualitative approach using van Manen’s phenomenology of practice. We uncovered the phenomenon through phenomenological interviews, which integrated narratives and illustrative episodes that reflected the lived experience of 20 survivors. Participants in the study were people who had undergone allogeneic hematopoietic progenitor cell transplantation, who were monitored on an outpatient basis and who met the following conditions: (i) were over 18 years old; (ii) had undergone SCT at least 3 months previously; (iii) had no evidence of disease relapse; (iv) were able to express themselves verbally, providing information relevant to the study, as well as expressing emotions and feelings. Descriptions of lived experiences were collected from participants between July 2020 and May 2021. In the phenomenological reflection on the lived descriptions, we followed the “stages” epoché, reduction, and vocative. Results: The following themes emerged from the ASCT survivor’s lived experience of comfort related to comfort care needs: continuous follow-up, reference nurse, information, assistance in adapting to the new self, mental health intervention, spiritual support, adaptation to changes in sexuality, physical rehabilitation, and job reintegration. Conclusion: This study reveals the importance of continuous follow-up for ASCT survivors. Survivors experience major changes in their lives in the long term and require a response from health professionals to find comfort in their daily lives.