Spine Surgery In Prone Position Research Articles

Effect of desflurane anesthesia on flash visual evoked potential monitoring in patients undergoing spine surgery: study protocol for a randomized controlled trial

BackgroundFlash visual evoked potentials (FVEPs) are a reliable method for protecting visual function during spine surgery in prone position. However, the popularization and application of FVEPs remain limited due to the unclear influence of various anesthetics on FVEPs. Exploring the effects of anesthetic drugs on FVEP and establishing appropriate anesthesia maintenance methods are particularly important for promoting and applying FVEP. According to the conventional concept, inhaled narcotic drugs significantly affect the success of FVEP monitoring, FVEP extraction, and interpretation. Nonetheless, our previous study demonstrated that sevoflurane-propofol balanced anesthesia was a practicable regimen for FVEPs. Desflurane is widely used in general anesthesia for its rapid recovery properties. As the effect of desflurane on FVEP remains unclear, this trial will investigate the effect of different inhaled concentrations of desflurane anesthesia on amplitude of FVEPs during spine surgery, aiming to identify more feasible anesthesia schemes for the clinical application of FVEP.Methods/ designA total of 70 patients undergoing elective spinal surgery will be enrolled in this prospective, randomized controlled, open-label, patient-assessor-blinded, superiority trial and randomly assigned to the low inhaled concentration of desflurane group (LD group) maintained with desflurane-propofolremifentanil-balanced anesthesia or high inhaled concentration of desflurane group (HD group) maintained with desflurane-remifentanil anesthesia maintenance group at a ratio of 1:1. All patients will be monitored for intraoperative FVEPs, and the baseline will be measured half an hour after induction under total intravenous anesthesia (TIVA). After that, patients will receive 0.5 minimum alveolar concentration (MAC) of desflurane combined with propofol and remifentanil for anesthesia maintenance in the LD group, while 0.7–1.0 MAC of desflurane and remifentanil will be maintained in the HD group. The primary outcome is the N75-P100 amplitude 1 h after the induction of anesthesia. We intend to use the dual measure evaluation, dual data entry, and statistical analysis by double trained assessors to ensure the reliability and accuracy of the results.DiscussionThis randomized controlled trial aims to explore the superiority effect of low inhaled concentration of desflurane combined with propofolremifentanil-balanced anesthesia versus high inhaled concentration of desflurane combined with remifentanil anesthesia on amplitude of FVEPs. The study is meant to be published in a peer-reviewed journal and might guide the anesthetic regimen for FVEPs. The conclusion is expected to provide high-quality evidence for the effect of desflurane on FVEPs and aim to explore more feasible anesthesia schemes for the clinical application of FVEPs and visual function protection.Trial registrationThis study was registered on clinicaltrials.gov on July 15, 2022. ClinicalTrials.gov Identifier: NCT05465330.

Limited effect of sugammadex on postoperative pulmonary complications in patients undergoing spine surgery in prone position intraoperatively: A retrospective analysis of matched cohort data.

Postoperative pulmonary complications (PPCs) increase postoperative mortality, hospital stays, and healthcare costs. Whether the use of sugammadex could reduce PPCs remains controversial. This study aimed to determine if sugammadex could more effectively reduce PPCs than acetylcholinesterase inhibitor (AChEi) in patients who had undergone spine surgery, in prone position intraoperatively. From March 2019 to February 2021, adult patients who underwent elective spine surgery were eligible. Primary outcomes were PPCs (including atelectasis on chest radiograph, pneumonia, acute respiratory distress syndrome, and aspiration pneumonitis) and respiratory failure that occurred within 28 days after surgery. Secondary outcomes were length of hospital stay, in-hospital death, and readmission rate within 30 days. Patients were divided into 2 groups (Sugammadex group and AChEi group) and compared by 1:1 propensity score matching. Of a total of 823 patients who underwent spinal surgery, 627 were included. After 1:1 propensity matching, 142 patients were extracted for each group. PPCs occurred in 9 (6.3%) patients in both groups (P = 1.000). Respiratory failure occurred in 7 (4.9%) patients in the Sugammadex group and 5 (3.5%) patients in the AChEi group (P = .77). There was no significant difference in secondary outcomes between the 2 groups. Although there have been some evidences showing that the use of sugammadex can attenuate the development of PPCs, this study did not show positive effects of sugammadex on patients who underwent spine surgery in the prone position.

Anesthetic management of 6-year child with right ventricular hypoplastic syndrome posted for spine surgery in prone position.

Anesthetic management of 6-year child with right ventricular hypoplastic syndrome posted for spine surgery in prone position.

The spine intra-abdominal pressure (SIAP) trial. A prospective, observational, single arm, monocenter study looking at the evolutions of the IAP prior, during and after spine surgery

Background and aimsBoth anaesthesiologists and spine surgeons consider the intra-abdominal pressure (IAP) as an important peri-operative factor affected by patient positioning.We assessed the change in IAP caused by using a thoraco pelvic support (inflatable prone support, IPS) with the subject under general anesthesia. The IAP was measured before, during and immediately after surgery. MethodsThe Spine Intra-Abdominal Pressure study (SIAP trial) is a prospective, single-arm, monocenter, observational study looking at changes in IAP prior, during and after spine surgery. The objective is to assess the change in IAP, measured via an indwelling urinary catheter, using the inflatable prone support (IPS) device during prone positioning of patients in spinal surgery. ResultsForty (40) subjects requiring elective lumbar spine surgery in prone position were enrolled after providing informed consent. The inflation of the IPS results in a significant decrease of IAP (from a median of 9.2 mmHg to 6.46 mmHg (p < 0.001)) in patients undergoing spine surgery in prone position. This decrease in IAP was maintained throughout the procedure despite the discontinuation of muscle relaxants. No serious adverse events or unexpected adverse events occurred. ConclusionThe use of the thoraco-pelvic support IPS device was able to significantly lower the IAP during spine surgery.

Postoperative delayed neurocognitive recovery: Evaluation of its incidence and correlation with intraoperative cerebral desaturation − A prospective observational study

Delayed neurocognitive recovery (DNR) is commonly seen in patients in the postoperative period. Literature has shown that monitoring cerebral desaturation intraoperatively can predict the development of DNR in elderly patients undergoing surgery in prone position. This prospective observational study was conducted in patients of all ages, with the primary objective to determine the incidence of DNR and its correlation with cerebral oximetry. The secondary objectives were to determine if intraoperative cerebral desaturation influenced the neuropsychometric variables from preoperative to postoperative period. This study included 61 patients, aged >18 years undergoing spinal surgery in prone position. An evening before surgery and at 48h postoperatively, patients were subjected to neuropsychological examination; Hindi Mental State Examination, Colour Trail Test 1 (CTT 1), CTT 2, Auditory Verbal Learning (AVLT) tests conducted by principal investigator (PI). DNR was defined as a 20% change in any of the test scores from the baseline. rSO2 was recorded bilaterally every 10min throughout surgery by an independent person. Cerebral desaturation was defined as a 20% drop in rSO2 from the control value. The incidence of DNR was 24.6%. The duration of anesthesia and cerebral desaturation were found to be independently predictive of DNR, with each hour of anesthesia causing a two-fold increase in the chances of development DNR (P=0.019) and presence of cerebral desaturation causing a 6-fold increase (P=0.039). CTT 1 and CTT 2 tests had significantly larger increase in test scores in the postoperative period, in patients with cerebral desaturation. Duration of anesthesia and cerebral desaturation were factors predictive of the development of DNR in patients undergoing spine surgery in prone position.

Intraoperative cardiac arrest in the prone position in neurosurgery: A reel challenge for the anesthesiologist

The Cardiac Arrest in Elective Neurosurgery, is complex and different from other types, as it’s influenced by the patient’s position, the surgical procedure, and the equipment used to fix the skull;&#x0D; we report a case of a patient admitted for lumbar spine surgery in prone position who presented an intraoperative cardiac arrest.&#x0D; chest compressions can be started immediately for prone patients; some studies confirmed the efficacy of back compressions but patients should be turned supine if possible.&#x0D; When defibrillation were necessary in patients ventilated in the prone position, defibrillation should be attempted, as placing the patient in the supine position would take precious minutes and would reduce the chances of successful defibrillation.&#x0D; Evidence is rare when dealing with neurosurgical patients, and more efforts are needed in understanding the etiologies, mechanisms and the specificities of its management.

Differential diagnosis of intraoperative cardiac arrest after spine surgery in prone position

Intraoperative cardiac arrest is one of the most feared events by anesthesiologists and surgeons. Although there are many possible causes, three differential diagnoses stand out in the presented scenario: pulmonary embolism, gas embolism, and acute myocardial infarction. A 61-year-old female patient was admitted in the hospital to C2-C5 arthrodesis. Despite no major bleeding during surgery, immediately after supination the patient developed refractory hypotension, a decrease in end tidal CO2, progressive bradycardia that ultimately led to pulseless electrical activity. Resuscitation maneuvers were promptly performed, sustained return of spontaneous circulation was attained after 50 minutes, and the patient was transferred to the ICU. This paper discusses the main causes for an episode of cardiac arrest in the context of cervical arthrodesis, with a markedly prolonged resuscitation time, in which the patient survived.

A comparative study of hemodynamic stability through intraoperative fluid administration guided by stroke volume variation assessment versus conventional parameters in terms of inferior vena cava diameter and collapsibility index during spine surgery

Stroke volume variation (SVV) is a naturally occurring phenomenon, often used by anesthesiologists for hemodynamic response to intra-operative fluid administration. In a mechanically ventilated patient under general anesthesia, the arterial pulse pressure rises during inspiration and falls during expiration due to changes in intra-thoracic pressure secondary to positive pressure ventilation. : In this open labelled, parallel group, randomized controlled trial, we investigated the role of using SVV as a marker for optimal intra-operative fluid therapy versus the conventional parameters of hemodynamic monitoring i.e., blood pressure, pulse rate and urine output in patients undergoing major spinal surgery in prone position. It was a single centre study and each group consisted of 35 patients in the age group of 18 – 50 years having ASA grade I status and without any previous comorbidities. SVV was maintained between 10 to 13% and Non-Invasive Blood Pressure (NIBP) and pulse rate maintained within 20% of baseline pre-induction values. Ringer’s lactate solution was chosen as fluid therapy in both groups. : The study showed that the total amount of fluid infused to either group had no statistically significant difference; however, the change in Inferior vena cava maximum diameter (IVCmax) in patients of the SVV monitored group was significantly lower than the conventional arm, for a given amount of fluid in either group. (Levene’s test for equality of variance F = 45.46, test statistics for equality of means t = 3.86; p = 0.001) Moreover, those patients who were maintained on lower margin of SVV range had a remarkable decrease of collapsibility index of IVC compared to pre-operative values. (Spearman’s rank correlation r = 0.533; p = 0.001) Thus, SVV proves to be a surrogate marker of administering intravenous fluid per-operatively maintaining euvolemic status as reflected by subsequent IVC collapsibility index (CI) values obtained in patients undergoing spinal surgery.

Prone spine surgery in a morbidly obese patient: Anesthesia challenges and management

India is seeing a rapid epidemiological transition from underweight to overweight, with an overall prevalence of obesity reported to be 40.3%. Anesthesiology concerns in an obese patient are well known. We elaborate on the anesthesia management in a 68-year-old male patient with a body mass index of 66.3 kg/m2 who underwent spine surgery in prone position. Challenges faced ranged from the size of the table to the difficult airway, difficulty in positioning, maintenance of airway and ventilation, maintaining a free abdomen, and anesthesia management with meticulous use of anesthetic drugs for an uneventful recovery.

A Study to Evaluate Changes in Modified Mallampati Class in Patients Undergoing Spine Surgery in Prone Position.

Background: Perioperative airway changes due to anesthesia and surgery could change a normal airway at induction to a risky airway at extubation.Objectives: The objective is to evaluate primarily the degree of airway changes, as quantified by the modified Mallampati (MMP) class, after spine surgery in the prone position. Secondary to assess the time required for these changes to revert back to the preoperative state and their correlation with other demographic and surgical variables.Methods: The present prospective observational study was conducted in a tertiary care hospital after ethical approval and trial registration. Fifty ASA I and II patients aged 18-65 years of both sex and undergoing spine surgery in prone positions were included. Supine MMP grade was observed preoperatively and at one, two, four, 24, and 48 hours postoperatively.Statistical analysis: IBM SPSS version 22 (IBM Corp, Armonk, NY) was used.Mean values were compared using paired t-tests and medians by the Wilcoxon test. The Spearman correlation was used to assess a relationship. The time for recovery was analyzed by Kaplan-Meir analysis.Results: An increase in MMP grade was observed at one hour postoperatively in 46 (92%) patients. Changes reverted back in 45 (98%) patients by 24 hours postoperatively. A weak positive correlation with age, weight, body mass index, duration of surgery, perioperative drop in hemoglobin, and a moderate positive correlation with fluid administered and estimated blood loss was recorded.Conclusions: An increase in postoperative MMP occurs in the majority of patients undergoing prone position spine surgery which may persist up to 48 hours. So, more vigilance and caution are warranted should reintubation be needed postoperatively.

Abstract No.: ABS0586: Is pressure control ventilation better than volume control in patients undergoing spine surgery in prone position?

Background & Aims:Optimisation of intraoperative ventilation is feasible nowadays due to availability of several new modes in anaesthesia workstations. Spine surgery in prone position leads to pulmonary and haemodynamic alterations. The present study aimed to compare PCV and VCV modes of ventilation in patients undergoing spine surgeries.Methods:After obtaining approval from institutional ethics committee the present, prospective, randomised study was conducted in 50 adult patient of either sex, ASA I or II undergoing thoracic or lumbar spine surgery in prone position. Standard anaesthesia protocols using Thiopentone, Fentanyl and Vecuroniun was followed. Patients in VCV group (n=25) were ventilated with volume control mode with TV = 7 ml/kg, PEEP=5cm H2O, I: E=1:2 and respiratory rate adjusted to keep Et CO2 between 35-40 mmHg and FiO2 =0.4. While in PCV mode (n=25) patients were ventilated with similar settings except PIP was adjusted to determine TV=7ml/kg. Draeger Primus workstation was used.Results:Demographic profile, duration of surgery, intraoperative dry and fluid consumption were comparable in two groups. Peak inspiratory pressure was higher in VCV (20 vs 18) and dynamics compliance was low in VCV (31.3 vs 35.93). Minute ventilation, EtCO2, dead space, O2 saturation was comparable in two groups though alveolar oxygenation was better in PCV. Diastolicblood pressure was low in VCV. Postoperative PFT decreased in both groups but were comparable.Conclusion:PCV is better than VCV in maintaining intraoperative respiratory mechanisms but whether they offer long term benefit require more studies comprising of larger sample sizes.

The effects of body mass index on intraabdominal pressure and regional cerebral oxygen saturation in lumbar spine surgery in prone position

The effects of body mass index on intraabdominal pressure and regional cerebral oxygen saturation in lumbar spine surgery in prone position

Changes in stroke volume induced by lung recruitment maneuver can predict fluid responsiveness during intraoperative lung-protective ventilation in prone position

BackgroundThe present study aimed to evaluate the reliability of hemodynamic changes induced by lung recruitment maneuver (LRM) in predicting stroke volume (SV) increase after fluid loading (FL) in prone position.MethodsThirty patients undergoing spine surgery in prone position were enrolled. Lung-protective ventilation (tidal volume, 6–7 mL/kg; positive end-expiratory pressure, 5 cmH2O) was provided to all patients. LRM (30 cmH2O for 30 s) was performed. Hemodynamic variables including mean arterial pressure (MAP), heart rate, SV, SV variation (SVV), and pulse pressure variation (PPV) were simultaneously recorded before, during, and at 5 min after LRM and after FL (250 mL in 10 min). Receiver operating characteristic curves were generated to evaluate the predictability of SVV, PPV, and SV decrease by LRM (ΔSVLRM) for SV responders (SV increase after FL > 10%). The gray zone approach was applied for ΔSVLRM.ResultsAreas under the curve (AUCs) for ΔSVLRM, SVV, and PPV to predict SV responders were 0.778 (95% confidence interval: 0.590–0.909), 0.563 (0.371–0.743), and 0.502 (0.315–0.689), respectively. The optimal threshold for ΔSVLRM was 30% (sensitivity, 92.3%; specificity, 70.6%). With the gray zone approach, the inconclusive values ranged 25 to 75% for ΔSVLRM (including 50% of enrolled patients).ConclusionIn prone position, LRM-induced SV decrease predicted SV increase after FL with higher reliability than traditional dynamic indices. On the other hand, considering the relatively large gray zone in this study, future research is needed to further improve the clinical significance.Trial registrationUMIN Clinical Trial Registry UMIN000027966. Registered 28th June 2017.

A study to evaluate ocular changes in patients undergoing spine surgery in the prone position.

Background and Aims:AA present prospective study was conducted to evaluate ocular changes occurring in patients undergoing spine surgery in the prone position.Material and Methods:A total of 44 patients of either sex, belonging to American society of Anaesthesiology I and II (aged 18-60 years) scheduled for elective spine surgery in prone position were enrolled in the study. Baseline IOP and MAP measurement were taken prior to induction. After induction of anaesthesia patients were intubated using flexo-metallic tube of appropriate size. IOP and MAP were recorded after induction of anaesthesia, following completion of surgery and immediately after turning the patient supine and 30 min following extubation. Blood loss and duration of surgery was also noted. The OPP was derived using the formula (OPP = MAP-IOP). Ophthalmic examination was also performed using direct and indirect ophthalmoscopy on the day prior to surgery and on first post-operative day to rule out anterior ischemic optic neuropathy (AION), posterior ischemic optic neuropathy (PION), and retinal ischemia.Results:Mean IOP significantly increased (18.91 ± 3.56 mm Hg) (P < 0.001) at the end of surgery as compared to baseline value 12.85 ± 3.07 mm Hg. As a result mean OPP significantly reduced (75.12 ± 16.45) (P = 0.0018) at the end of the procedure.Conclusion:In patient’s undergoing spine surgery in the prone position, careful patient positioning with no extrinsic pressure on the eyes, minimal surgical time and blood loss, and prevention of intraoperative hypotension, should be ensured to prevent the IOP rise and a reduction in OPP which can further prevent post-operative visual disturbance.

The Effect of Goal-Directed Fluid Therapy versus Standard Fluid Therapy on the Cuff Leak Gradient in Patients Undergoing Complex Spine Surgery in Prone Position.

Objective Cuff leak test is an effective and established maneuver to predict airway edema. Standard fluid therapy (SFT) based on conventional monitoring is often associated with postoperative airway edema after complex spine surgeries. We conducted this prospective randomized controlled study to compare the effect of SFT versus goal-directed fluid therapy (GDFT) on the cuff leak gradient (CLG) in patients undergoing complex spine surgery in prone position. Our secondary objectives were to compare the effect of SFT and GDFT on sore throat, hoarseness, and length of intensive care unit (ICU) and hospital stay. Materials and Methods Thirty consecutive American Society of Anesthesiologists physical status I and II patients (18–60 years), of either sex, scheduled for spine surgery in prone position with expected duration of surgery more than 5 hours were included. The patients were randomized into two groups of 15 each. Group S patients ( n = 15) served as control group and received SFT intraoperatively, while patients in group G ( n = 15) received GDFT. Standard anesthetic protocol was followed in both the groups. The CLG was defined as the difference between the cuff leak volume (CLV) after intubation (CLV AI ) and before extubation (CLV BE ). Statistical Analysis and Results CLG was significantly less in group G (group S, 137.12 mL; group G, 65.52 mL; p -value <0.001). Intravenous fluids, blood loss, and postoperative sore throat were comparatively lesser in group G, though not statistically significant. Postoperative hoarseness was significantly lower in group G ( p -value = 0.003). Duration of ICU stay in group G (19.43 hours) was significantly lower ( p -value = 0.009) than group S (24.64 hours), but length of hospital stay was comparable. Conclusion GDFT significantly reduces airway edema and consequently reduces CLG as compared with SFT in patients undergoing complex spine surgery in prone position. Postoperatively, it also reduces sore throat, hoarseness of voice, and duration of ICU stay.

A Comparative Study of Extubation in Prone and Supine Position in Patients Undergoing Lumbar Spine Surgery in Prone Position

Aim: In case of surgeries done in prone position, patients are rolled to supine during extubation which is associated with loss of monitoring and hemodynamic change. Also, incidence of coughing and bucking are noted. Several studies have shown that prone position extubation is associated with reduced frequency of coughing and monitor disconnection in prone position surgeries. The purpose of this study was to compare the safety and efficacy of patients extubated in prone and supine posted for lumbar spine surgery.&#x0D; Study Design: 60 patients varying from age 18 - 65 years and posted for lumbar spine surgery under general anaesthesia in prone position were randomly allocated to any one of the two groups Group P - In this group extubation was done in prone position at the end of surgery or Group S – In this group extubation was done in supine position at the end of surgery.&#x0D; Place and Duration of Study: Jawaharlal Nehru Medical College, DMIMS (DU), Acharya Vinoba Bhave Rural Hospital (AVBRH), Datta Meghe Institute of Medical Sciences, Sawangi (M), Wardha over the period of 1 year (2019 - 2020).&#x0D; Methods: A double blinded randomized controlled comparative study was conducted on 60 patients with primary objective to measure incidence of coughing and severity of coughing in prone vs supine extubation. Patients were anesthetized with fentanyl, nitrous oxide, sevoflurane, and vecuronium. Neuromuscular blockade was reversed in prone position and all patients had spontaneous ventilation at the conclusion of surgery. At time 0, patients were randomly divided into group P or group S. Patients in the group S were then rolled over, while those in the prone position remained undisturbed. Frequency of cough, monitor disconnection and changes in heart rate (HR) and mean arterial pressure (MAP) were noted during extubation. Patient were extubated on purposeful behaviour and eye opening.&#x0D; Results: Frequency of coughing was significantly less in prone patients in comparison to supine group (6 vs. 24 coughs) monitor disconnections dysconnectivity was also fewer (p &lt; 0.001), little change in haemodynamics was noted during extubation. Time to extubation from time 0 was comparatively more in Group S. Airway rescue was not needed.&#x0D; Conclusions: Extubation in prone position is associated with lesser frequency of coughing, disruption of monitors and significantly less hemodynamic changes as compared to supine position extubation he abstract should be concise and informative. It should not exceed 300 words in length. It should briefly describe the purpose of the work, techniques and methods used, major findings with important data and conclusions. Different sub-sections, as given below, should be used. No references should be cited in this part. Generally non-standard abbreviations should not be used, if necessary they should be clearly defined in the abstract, at first use.

Comparison of upper and lower body forced air blanket to prevent perioperative hypothermia in patients who underwent spinal surgery in prone position: a randomized controlled trial

BackgroundWe compared upper- and lower-body forced-air blankets in terms of their ability to prevent perioperative hypothermia, defined as a reduction in body temperature to < 36.0°C, during the perioperative period in patients undergoing spine surgery in the prone position.MethodsIn total, 120 patients scheduled for elective spine surgery under general anesthesia were divided into an upper-warming group (n = 60) and a lower-warming group (n = 60). After inducing anesthesia and preparing the patient for surgery, including prone positioning, the upper and lower bodies of the patients in the upper- and lower-warming groups, respectively, were warmed using a forced-air warmer with specified upper and lower blankets. Body temperature was measured using a tympanic membrane thermometer during the pre- and post-operative periods and using a nasopharyngeal temperature probe during the intraoperative period. Patients were evaluated in terms of shivering, thermal comfort, and satisfaction in the post-anesthesia care unit (PACU).ResultsThe incidence of intraoperative and postoperative hypothermia was lower in the upper-warming group than in the lower-warming group ([55.2% vs. 75.9%, P = 0.019] and [21.4% vs. 49.1%, P = 0.002]). Perioperative body temperature was higher in the upper-warming group (P < 0.001). However, intraoperative blood loss, postoperative thermal comfort scale and shivering scores, patient satisfaction, and PACU duration were similar in the two groups.ConclusionsThe upper-body blanket was more effective than the lower-body blanket for preventing perioperative hypothermia in patients who underwent spine surgery in the prone position.

A Rare Cause of Inguinal Hernia Recurrence: Herniation After Lumbar Spinal Surgery in Prone Position

A Rare Cause of Inguinal Hernia Recurrence: Herniation After Lumbar Spinal Surgery in Prone Position

Risk Factors for Facial Pressure Ulcers in Patients Who Underwent Prolonged Prone Orthopedic Spine Surgery.

This study evaluated incidence and risk factors associated with the development of facial pressure ulcers (FPU) in patients who underwent spine surgery in prone position. A total of 300 cases were studied. The incidence of FPU after prone spine surgery using head padded device >3 hours was 27.3%. Hypotension, higher temperature, prolonged operation time, and much crystalloid therapy were the independent risk factors.

Pressure Controlled Ventilation versus Volume-Controlled Ventilation Regarding Hemodynamics and Stress Response for Posterior Lumbar Spine Surgeries in The Prone Position

Background: Prone positioning may induce alterations of airway pressures and hemodynamic that may affect intraoperative blood loss. Ventilation mode may modify these alterations. Objective: Our study aimed to differences between pressure-controlled ventilation (PCV) and volume-controlled ventilation (VCV) in their effects on hemodynamic changes during posterior lumbar surgeries performed in the prone position. Patients and Methods: This is a prospective randomized controlled study, which was performed in the Department of Anaesthesiology and Surgical ICU, Aswan university, Egypt at the duration from 1-6-2017 to 13-12-2018 for 60 patients who had posterior lumbar spine surgery in prone position who were eligible to inclusion/exclusion criteria divided into two groups; Group (I) were received VCV mode (n = 30) and Group (II) were received PCV mode (n = 30) then study parameters were recorded intraoperatively and postoperatively in the two groups of ventilation modes. Results: As regarding heart rate, mean arterial blood pressure, serum glucose level, and serum cortisol level, they were statistically significantly lower in PCV group than VCV group both intraoperative and postoperative which reflects that stress response is lower with PCV more than VCV and that may have also a rule in decreasing intraoperative blood loss and improving the surgical field in these surgeries. Conclusions: for lumbar spine surgeries in the prone position, PCV was associated with decreased HR, blood pressure, cortisol, glucose levels compared with VCV. The stress response is lesser with PCV which is better for this type of patients.