The article is dedicated to the analysis of key problems and challenges in the field of public procurement for healthcare institutions. T h e r e l e v a n c e of the work is determined by the critical importance of ensuring the quality and safety of medical products, as well as the need to optimize procurement processes in the face of limited budgets. The research subject is the issues of public procurement activities in healthcare institutions with a focus on process optimization, legal and economic aspects, and the application of modern technologies within an interdisciplinary approach. The aim of the study is to identify and analyze the most acute problems in the field of healthcare procurement and develop proposals for their solutions. M a t e r i a l s a n d m e t h o d s . The research includes a comprehensive analysis of literary sources, generalizations of practical experience and expert assessments. Methods of comparative analysis, systematization and generalization of the obtained data are used to identify key problems and challenges. The research r e s u l t s indicate a number of problems in the procurement sphere, including: the risk of acquiring counterfeit or substandard medical products, the need to improve the qualifications of procurement specialists, and difficulties in developing detailed technical specifications. Measures to improve the situation are proposed, including the development of detailed technical specifications in collaboration with medical experts, training of specialists, and strengthening quality control of products. The c o n c l u s i o n s of the study highlight the need for a comprehensive approach to solving procurement issues in healthcare, including improving the qualifications of specialists, strengthening interdepartmental cooperation, and implementing innovative technologies. The research results can be applied to improve the legislative framework and practice of conducting public procurement in the healthcare sector. T h e s c o p e o f t h e r e s u l t s . The results of the work can be used to improve the practice of public procurement in the healthcare system at the level of public medical institutions, and also provide a basis for further scientific work in this field.