Abstract For treating and diagnosing cardiovascular diseases, the field of biomedical engineering is significant because it develops new ways and techniques. Stenosis is the narrowing of an artery, and it leads reduction in the flow rate of blood. This study investigates the blood flow mechanism in an artery using a mathematical model of Carreau nanofluid with four distinct nanoparticles. Tetra nanofluid model produces significant advancement in the simulation of blood flow through the stenosed arteries. The model is capable of predicting the pressure drop and velocity distribution for diagnosing and treating stenosis. The spectral relaxation approach is used to present the model's efficiency and effectiveness, which makes it a suitable method for solving the governing equations of this study. The findings of this study have important implications for the development of new treatments and diagnostic techniques for stenosis and other cardiovascular diseases.
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