Spectral Group Frequencies Research Articles

IR and <sup>1</sup>H NMR Spectral Studies of some 2-Amino-4-Isopropyl-6-Methoxy-N-Phenylpyrimidine-5-Carboxamides: Assessment of Substituent Effects

A series of 2-Amino-4-isopropyl-6-methoxy-N-phenylpyrimidine-5-carboxamide compounds have been synthesized from various substituted dithioacetal and guanidine. The purities of these compounds were checked by their physical constants, UV, IR, NMR and MASS spectral data. The IR and 1HNMR spectral data of these compounds have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed.

IR and <sup>1</sup>H NMR Spectral Studies of some 2-Amino-4-Isopropyl-6-Methoxy-N-Phenylpyrimidine-5-Carboxamides: Assessment of Substituent Effects

A series of 2-Amino-4-isopropyl-6-methoxy-N-phenylpyrimidine-5-carboxamide compounds have been synthesized from various substituted dithioacetal and guanidine. The purities of these compounds were checked by their physical constants, UV, IR, NMR and MASS spectral data. The IR and 1HNMR spectral data of these compounds have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed.

Spectral QSAR and QPR Study of some (<i>E</i>)-4-(((2-Hydroxy-6-(Substituted Phenyl)-1,6 Dihydropyrimidin-4-yl)Methyl)Diazenyl)Benzoic Acid Derivatives

A series of titled compounds were synthesized and recorded the infrared and NMR spectra. The assigned spectral group frequencies were correlated with Hammett substituent constants, F and R parameter. From the statistical analysis results, the effect of substituents on the spectral group frequencies has been studied.

Spectral QSAR and QPR Study of some (<i>E</i>)-4-(((2-Hydroxy-6-(Substituted Phenyl)-1,6 Dihydropyrimidin-4-yl)Methyl)Diazenyl)Benzoic Acid Derivatives

A series of titled compounds were synthesized and recorded the infrared and NMR spectra. The assigned spectral group frequencies were correlated with Hammett substituent constants, F and R parameter. From the statistical analysis results, the effect of substituents on the spectral group frequencies has been studied.

SOCl<sub>2</sub> catalyzed cyclization of chalcones: Synthesis and spectral studies of some bio-potent <sup>1</sup><i>H</i> pyrazoles

Some aryl-aryl 1H pyrazoles have been synthesised by cyclization of aryl chalcones and hydrazine hydrate in the presence of SOCl2. The yields of the pyrazoles are more than 85%. These pyrazoles are characterized by their physical constants and spectral data. The infrared, NMR spectral group frequencies of these pyrazolines have been correlated with Hammett substituent constants, F and R parameters. From the results of statistical analyses the effects of substituent on the spectral frequencies have been studied. The antimicrobial activities of all synthesised pyrazolines have been studied using Bauer-Kirby method. KEY WORDS: SOCl2, 1H Pyrazolines, IR spectra, NMR spectra, Hammett substituent constants, Antimicrobial activities Bull. Chem. Soc. Ethiop. 2014, 28(2), 271-288. DOI: http://dx.doi.org/10.4314/bcse.v28i2.11

Infrared and <sup>13</sup>C NMR Spectral Studies of some Aryl Hydrazides: Assessment of Substituent Effects

A series of some aryl hydrazides have been synthesized. These hydrazides purities were analyzed by physical constants and spectral data. The assigned spectral group frequencies were correlated with Hammett substituent constants and Swain-Lupton parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the spectral group frequencies has been discussed

Infrared and <sup>13</sup>C NMR Spectral Studies of some Aryl Hydrazides: Assessment of Substituent Effects

A series of some aryl hydrazides have been synthesized. These hydrazides purities were analyzed by physical constants and spectral data. The assigned spectral group frequencies were correlated with Hammett substituent constants and Swain-Lupton parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the spectral group frequencies has been discussed

Spectral Correlations in some Substituted Styryl (<i>E</i>)-4-((2-Oxopropyl)Diazenyl) Benzoic Acids

A series of titled compounds were prepared and analyzed their purities by literature method. The infrared and NMR spectral group frequencies of the compounds were assigned and correlated with Hammett substituent constants, F and R constants using single and multi linear regression analysis. From the results of statistical analysis, the effect of substituents on the above spectral frequencies was discussed.

Spectral Correlations in some Substituted Styryl (<i>E</i>)-4-((2-Oxopropyl)Diazenyl) Benzoic Acids

A series of titled compounds were prepared and analyzed their purities by literature method. The infrared and NMR spectral group frequencies of the compounds were assigned and correlated with Hammett substituent constants, F and R constants using single and multi linear regression analysis. From the results of statistical analysis, the effect of substituents on the above spectral frequencies was discussed.

Assessment of Substituent Effects and Antimicrobial Activities of some 2ʹ,5ʹ-Dimethyl Phenyl Chalcones

Some 2ʹ,5ʹ-dimethyl phenyl chalcones have been synthesized by Crossed-Aldol condensation between 2,5-dimethyl acetophenone and various substituted benzaldehydes using catalytic amount of sodium hydroxide and ethanol. The yields of the chalcones are more than 93%. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method

Solvent-Free Synthesis and Assessment of Substituent Effects from IR & NMR Spectra of some Substituted Benzylidene-5-Ethyl-1,3,4-Thiadiazole-2-Amines

A series containing ten titled compounds were synthesized by SiO2:H3PO4 catalyzed solvent-free condensation of substituted benzaldehydes and 2-amino-5-ethyl-1,3,4-thiadiazole under microwave irradiation. The yields of prepared amines are more than 90%. The synthesized amines were characterized by their physical constants and spectroscopic data reported in literature earlier for known compounds. The assigned spectral group frequencies such as infrared νC=N, C-S-C, N-N (cm-1) and NMR chemical shifts (δ, ppm) of CH, C=N have been correlated with Hammett substituent constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analyses, the effects of substituent on the above spectral data have been discussed.

Assessment of Substituent Effects and Antimicrobial Activities of some 2ʹ,5ʹ-Dimethyl Phenyl Chalcones

Some 2ʹ,5ʹ-dimethyl phenyl chalcones have been synthesized by Crossed-Aldol condensation between 2,5-dimethyl acetophenone and various substituted benzaldehydes using catalytic amount of sodium hydroxide and ethanol. The yields of the chalcones are more than 93%. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method

Solvent-Free Synthesis and Assessment of Substituent Effects from IR & NMR Spectra of some Substituted Benzylidene-5-Ethyl-1,3,4-Thiadiazole-2-Amines

A series containing ten titled compounds were synthesized by SiO2:H3PO4 catalyzed solvent-free condensation of substituted benzaldehydes and 2-amino-5-ethyl-1,3,4-thiadiazole under microwave irradiation. The yields of prepared amines are more than 90%. The synthesized amines were characterized by their physical constants and spectroscopic data reported in literature earlier for known compounds. The assigned spectral group frequencies such as infrared νC=N, C-S-C, N-N (cm-1) and NMR chemical shifts (δ, ppm) of CH, C=N have been correlated with Hammett substituent constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analyses, the effects of substituent on the above spectral data have been discussed.

Spectral Correlation Analysis and Antimicrobial Activities of some 2,4-Dimethoxy Phenyl Chalcones

A series of 2,4-dimethoxy phenyl chalcones have been synthesized by Crossed-Aldol condensation of 2,4-dimethoxy phenyl and various substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.

Spectral Correlation Analysis and Antimicrobial Activities of some 2,4-Dimethoxy Phenyl Chalcones

A series of 2,4-dimethoxy phenyl chalcones have been synthesized by Crossed-Aldol condensation of 2,4-dimethoxy phenyl and various substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.

Spectral Correlations and Antimicrobial Activities of some 1-Pyrenyl Chalcones

A series of 1-pyrenyl chalcones have been synthesized by Crossed-Aldol condensation of 1-acetylpyrene and substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.

IR & NMR Spectral Studies of some 7-Substituted 9H-Fluorenacyl Bromides: Assessment of Substituent Effects

A series of some 2-bromo-1-(2-substituted 9H-fluorene-7-yl)ethanones have been prepared. The purities of these ethanones have been checked by their physical constants and spectroscopic data. The spectral group frequencies of these enones have been assigned and correlated with Hammett substituent constants, F and R parameters. From the results of statistical analyses, the effects of substituent have been discussed.

IR & NMR Spectral Studies of some 7-Substituted 9H-Fluorenacyl Bromides: Assessment of Substituent Effects

A series of some 2-bromo-1-(2-substituted 9H-fluorene-7-yl)ethanones have been prepared. The purities of these ethanones have been checked by their physical constants and spectroscopic data. The spectral group frequencies of these enones have been assigned and correlated with Hammett substituent constants, F and R parameters. From the results of statistical analyses, the effects of substituent have been discussed.

Spectral Correlations and Antimicrobial Activities of some 1-Pyrenyl Chalcones

A series of 1-pyrenyl chalcones have been synthesized by Crossed-Aldol condensation of 1-acetylpyrene and substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.