Specific Preventive Measures Research Articles

Common Faults and Maintenance of Three-phase AC Asynchronous Motors

Application of three-phase AC asynchronous motor in industrial applied in many aspect following function that need to use. In operation use, many troubles may cause motor equipment not to operate or break down by the motor itself or caused by a system including protection, control system, interlocking device, and others causes. Aiming at the actual situation that three-phase AC asynchronous motors are widely used and have a high failure rate, this paper focuses on analyzing the common failures and abnormal phenomena of three-phase AC asynchronous motors and their main causes. This Research Method is reinforced by the actual monitoring of the locality where the equipment is installed. At the same time, some specific preventive measures and treatment methods are proposed to timely discover and eliminate the potential accidents of motors as much as possible and ensure the safe operation of motors. In conclusion, the aspects that need to be considered are one by one. There are 2 general classifications to determine possible faults, the first is about the operating conditions that the equipment motor should monitor and take the scheduled data to know about the actual conditions including power quality, temperature rise, vibration analysis, and physical abnormalities during the operation of the unit.

Cause Analysis and Preventive Measures for Deterioration of Steam Turbine Lubricating Oil

Lubricating the oil system of the steam turbine in the power plant is an important part of maintaining the normal operation of a steam turbine. The quality of oil directly affects the safe and stable operation of steam turbines. If the oil quality deteriorates, it is very easy to cause major accidents such as wear of steam turbine bearings, jamming of the speed control system, and even burning of bearings, failure of steam turbine speed control system leading to overspeed. This research method uses a literature review. In the operation of the power plant, it is common for lubricating oil to exceed the standard particle size and water content, and there are many reasons for this. This article analyzes the causes of lubricating oil deterioration and explains more specific preventive measures. Conclusion Deterioration in oil quality and excessive particle size can easily lead to serious consequences. Therefore, it must be controlled from the inspection of new oil entering the factory, sampling and testing, and monitoring of the operation stage, to improve the maintenance process.

Sex-disaggregated analysis of central venous catheter-related bloodstream infections in patients with cancer.

Men are generally more susceptible to bacterial infections than women. Central venous catheters (CVCs), often used to administer systemic treatment in patients with cancer, are an important source of infection. However, little is known about sex-specific differences of CVC-related bloodstream infections (CRBSIs) in patients with cancer. This study aimed to compare CRBSIs in men vs. women in a large cohort of patients with cancer. Data were derived from the SECRECY registry including non-selected patients with centrally inserted non-tunneled internal jugular or subclavian vein CVCs in 10 hematology and oncology sites in Germany. Only CRBSIs classified as definite CRBSI (dCRBSI) or probable CRBSI were included, and the combination of both was summarized as dpCRBSI. CVCs were matched 1:1 for underlying disease, anatomic site of CVC insertion, type of CVC dressing, antimicrobial coated CVC, complicated CVC insertion and CVC in situ time by propensity score matching (PSM). Endpoints were CRBSI rates and incidences in CVCs inserted in men vs. women. A total of 5075 CVCs registered from March 2013 to March 2024 were included in the analysis, of which 3024 comprises the PSM cohort. 1512 (50.0%) CVCs were inserted in men. Underlying diseases mainly were hematological malignancies (96.4%). While there was no statistically significant difference between men and women in the dCRBSI rate (5.4% vs. 4.1%; p=0.12) and the dCRBSI incidence (3.8 vs. 2.9/1000 CVC days; p=0.11), the rate of dpCRBSI (9.9% vs. 6.7%; p=0.002) and the dpCRBSI incidence (7.0 vs. 4.7/1000 CVC days; p=0.002) were significantly higher in men vs. women. The proportion of coagulase-negative staphylococci as causative agent of both dCRBSI and dpCRBSI was higher in men than in women (58.8% vs. 41.2%; p=0.07, and 61.5% vs. 38.5%; p=0.002, respectively). A multivariable regression revealed neutropenia as an independent risk factor for dCRBSI and male sex as risk factor for dCRBSI and dpCRBSI. In patients with hematological malignancies, men have a higher risk of CRBSI than women. This finding may be attributed to the high number of jugular vein inserted CVCs which in men may be associated with higher rates of skin colonization than in women. Special preventive measures such as earlier removal of CVCs in men may be studied in future.

Molecular mechanisms of ferroptosis in renal ischemia-reperfusion injury Investigated via bioinformatics analysis and animal experiments.

Kidney transplantation is a pivotal treatment for end-stage renal disease. However, renal ischemia-reperfusion injury (IRI) during surgery significantly impacts graft function. Despite unclear molecular mechanisms, no specific therapies or preventative measures are available. Gene expression profiles from renal biopsies before and after IRI were downloaded from public databases. Differentially expressed genes were identified using the Wilcoxon rank-sum test and weighted gene co-expression network analysis. Ferroptosis-associated genes were screened using the FerrDb database. The genes with the highest connectivity were identified via the protein-protein interaction (PPI) network and upstream regulatory miRNAs were found through the gene-miRNA network. A mouse renal IRI model was constructed for transcriptome sequencing and quantitative real-time polymerase chain reaction (qRT-PCR) validation to elucidate the relationship between key ferroptosis genes and regulatory miRNAs in renal IRI. Differential analysis identified 15 ferroptosis-associated genes (TNFAIP3, IL6, KLF2, EGR1, JUN, ZFP36, GDF15, CDKN1A, HSPB1, BRD2, PDK4, DUSP1, SLC2A3, DDIT3, and CXCL2) involved in renal IRI regulation. In animal experiments, ferroptosis-related genes were also upregulated in the model group. Enrichment analysis and hematoxylin-eosin pathological staining suggested these genes are primarily involved in renal inflammatory responses. PPI network analysis revealed IL6 as the gene with the highest connectivity, and the gene-miRNA network indicated IL6 might be regulated by miR-let-7a. Animal experiments revealed decreased miR-let-7a and increased IL6 levels in the model group, identifying potential therapeutic targets. MiR-let-7a regulates ferroptosis in renal IRI by targeting IL6, highlighting IL6 as a crucial gene in the ferroptosis process of renal IRI.

The UFair-Questionnaire: Perceived university fairness and its association with mental health

Abstract Introduction University students face different stressors that might jeopardise their mental health. Hitherto, mainly general stress perceptions were assessed, which appeared inappropriate to indicate stress directly linked to the university or for deriving specific preventative measures. The aim of this study was to adapt the concept of organisational justice to universities, develop and validate a corresponding questionnaire (UFair: University Fairness Questionnaire), and estimate its association with mental health. Methods In total, 1,105 students (average age: 25.5 years [SD: 5.43]; female: 50.1%; university: 67.2%, university of applied sciences: 32.8%) were surveyed online. Perceived unfairness at the university was measured using the newly developed 20 item UFair Questionnaire. Mental health was measured using the Patient Health Questionnaire (PHQ-8, depression) and Maslach Burnout Inventory for Students (MBI-SS, burnout). Linear regression models estimated the adjusted (age, gender, type of university, lifestyle factors) relationship between perceived university injustice and mental health indicators. Results The UFair questionnaire showed good psychometric properties (Cronbach’s alpha = .960) and a unidimensional factor structure. There was a considerable association with depression (beta = .485; p < .001; R2 = .261) and burnout (beta = .481; p < .001; R2 = .250). Conclusions Perceived injustice represents not only a stressor at the workplace but also in the university setting, showing a considerable relationship with students’ mental health. University justice includes the perception of organisational aspects, the treatment of students, and consideration of the individual situation of students. The relevance of these aspects to the health of students should be recognised and taken into account by universities. The valid measurement by the UFair Questionnaire represents the basis for possible preventive approaches and interventions. Key messages • Organisational injustice exists not only in the workplace but also among students in the university setting. • Perceived unfairness among students is associated with depression and burnout.

Dengue fefer and mixed abortion among pregnant women: findgs of a comparative cross-sectional study

Background: Dengue situation in Bangladesh has escalated over the last few years causing significant mortality and morbidity. Pregnant women are highly vulnerable to dengue infection leading to various grave complications for both mother and foetus including missed abortion. Despite the severity of this condition, few studies have explored the association of dengue fever with missed abortion in Bangladesh. This study aimed to investigate the association between missed abortion and dengue fever. Methods: This comparative cross-sectional study enrolled 35 pregnant women having the history of missed abortion during the gestational age of less than 22 weeks and 35 pregnant women continuing their pregnancy with gestational age of more than 22 weeks receiving ante natal care. Both groups were selected conveniently. The study was conducted in a private facility from February to October, 2023. Data were collected from medical record review and analyzed with appropriate descriptive and analytical statistics. Cases of missed abortion attributed to dengue infection were compared with pregnant women receiving routine antenatal care if their pregnancies continued beyond 22 weeks’ gestation. Other predictive factors for missed abortion were also examined. Results: Dengue infection was detected among 14 (40%) of pregnant women with missed abortion in comparison to 3 (8.6%) pregnant women without missed abortion. Significant (p<0.05) association was found between dengue infection and missed abortion in pregnant women. Conclusion: Special preventive measures should be taken to protect pregnant mother against dengue infection. JOPSOM 2023; 42(1):62-67

Landslide susceptibility mapping and similar case matching based on case library: a case study of Xinjing landslide, China

Landslide susceptibility mapping (LSM) predicts potential landslide risks based on historical landslides, playing a crucial role in landslide prevention and control. This study proposes a novel approach for LSM in open-pit mines, leveraging a comprehensive landslide case database. This method addresses the limitations of traditional LSM approaches, such as sensitivity to historical landslide records, low-quality inventories, and limited dataset size. By expanding the training set and incorporating case-based reasoning (CB-LSM) using Long Short-Term Memory (LSTM) for machine learning, the model demonstrated a 10% improvement in predictive accuracy compared to statistical models, showing strong applicability even in areas with low-quality landslide inventories. Additionally, this study enhances the practical utility of LSM by introducing a similar case matching method, employing Fuzzy C-Means (FCM) clustering, which links high-risk areas identified by LSM with specific landslide prevention measures. The proposed approach not only improves the accuracy of landslide predictions but also strengthens the connection between LSM results and effective landslide prevention strategies. Given the higher risks associated with landslides in open-pit mines, the proposed method significantly lowers the threshold for applying LSM in these environments, offering a valuable tool for safeguarding personnel and property.

Pertussis is still not a completely controlled infection

The lecture focuses on pertussis, an infection managed by specific preventive measures, which continues to threaten both child and maternal health, as well as overall healthcare system. Despite high vaccination rates, pertussis remains an “under-controlled” infection and a significant contributor to childhood morbidity and mortality. Moreover, in many countries, the incidence of pertussis is clearly rising among both children and adults, with a notable proportion of cases occurring in vaccinated individuals. This increase may be associated with changes in the antigenic structure of the pathogen, the limited duration of post-vaccination immunity, reduced vaccination coverage, and the use of more sensitive laboratory diagnostic methods. The lecture addresses modern aspects of the etiopathogenesis, epidemiology, clinical presentation, diagnosis, treatment, and prevention of pertussis. Given the rising incidence of this infection in Russia and several other countries in 2023, the information presented will be especially valuable for practitioners, particularly family doctors.

Investigation of probable Salmonella outbreak in the National Cancer Institute, Sri Lanka

Abstract Background An outbreak is the occurrence of case of disease in excess of what would normally be expected in a defined community. Outbreaks in immune compromised population can lead to devastating morbidity and mortality. Infection prevention and control (IPC) team has a pivotal role in both averting and managing outbreaks in health care settings. There were 7 cases of Salmonella spp, isolated from blood and stools since 12th July 2023 up to 11th August. Assuming of a possible outbreak, IPC team decided to investigate in order to find a possible source for the outbreak. Methods As soon as the outbreak was confirmed, immediate relevant control measures were taken after studying the available information. Working case definitions was constructed with clinical criteria and laboratory criteria with restrictions by time, place and person. Different categories of case definitions were used as the diagnosis was uncertain, such as “confirmed”, “probable” and “possible”. Active surveillance was conducted to collect information on additional case. Data collection tool was prepared with demographic information, clinical information and risk factor information. Then more cases were detected and line listing was created to organize important information for the investigation. Epidemic curve was drawn to see the pattern of spread and it was an irregularly jagged curve which interprets as intermittent common source epidemic. Specific control and prevention measures were implemented. Inquiries were made regarding the dietary intake of the patients over the last seven days and it was difficult to find a common source of food item however, all patients have consumed food prepared in the hospital kitchen. Therefore an audit was conducted in the hospital kitchen to identify probable source. Kitchen staff was educated about the food safety measures and personal hygiene. Kitchen staff was screened for Salmonella carrier state in their stool. Quality of the water from the kitchen and wards was checked for fecal contamination. No residual food was available for microbiological testing. Hypothesis was formulated to gather information after discussion with patients and staff. Findings were communicated to all relevant parties including Director and clinicians in the hospital. Salmonella isolates were sent to the Enteric Reference Laboratory, Medical Research Institute, Colombo for serotype identification. Results It was difficult find a common source. There were some malpractices in the kitchen and those were corrected immediately. Water quality in the hospital was satisfactory. Kitchen staff were not colonized with salmonella. However egg supplier to the kitchen was changed recently and eggs were supplied last minute and the eggs were not washed prior to cooking. Three isolates sent to the reference laboratory were identified as Salmonella Weltevreden, one as Salmonella Enteritidis, while the remaining three isolates could not be identified to serotype level with the available resources. Conclusion The exact contributory factor to the outbreak remained elusive. However, numerous food safety issues which can lead to cross contamination during the preparation of food were identified. Consequently, prompt investigation and control measures are essential to prevent further food borne outbreaks.

A tentative exploration for the association between influenza virus infection and SARS-CoV-2 infection in Shihezi, China: A test-negative study

The outbreak of respiratory diseases, such as COVID-19 and influenza, has drawn global attention. However, it remains unclear whether the risk of influenza A infection may be affected by the history of SARS-CoV-2 infection. In this study, we conducted a test-negative case-control study, and utilized a logistic regression model to analyze the relationship between SARS-CoV-2 and influenza A infections. Among 258 eligible patient samples with influenza-like illness (ILI), we did not detect a statistically significant association between the history of SARS-CoV-2 infection and the risk of influenza A infection. These findings might indicate that antibodies against COVID-19 acquired through vaccination or natural immunity have not protected against influenza.

Ранние и отдаленные результаты профилактики абдоминального компартмент-синдрома у пациентов с W3 вентральными грыжами

Abdominal compartment syndrome is a severe pathology requiring special preventive and treatment measures. The development of methods for the prevention of abdominal compartment syndrome is important in patients with W3 ventral hernias and loss of the domain. The study analyzed the results of treatment of 71 patients with W3 hernias of the anterior abdominal wall. Before surgery, all patients were calculated the size of the hernia implant necessary for the prevention of compartment syndrome. To calculate the size of the required hernia implant, radiography, ultrasonography and anthropometric data of the patient were used. The patients underwent hernioplasty with sublay, inlay and, developed by the authors, in a combined method. In the groups with inlay and combined method hernioplasty, the development of compartment syndrome was not observed. The combination of the developed methods of preoperative calculation of the hernia implant and the combined method of hernioplasty showed a low number of early and late postoperative complications, the same as in other study groups. The results obtained indicate the effectiveness of the developed methods for the prevention of abdominal compartment syndrome.

Risk groups of HIV infection among the population of the Omsk region

The peculiarities of the course of the epidemic process of HIV infection, including the formation of certain risk groups by gender, age and social status, are relevant, as they allow the development of specific preventive measures. The aim is to identify risk groups for HIV infection among the population of the Omsk region in 1996–2023. Data from the main statistical reporting forms, the Federal Register of Persons Infected with the Human Immunodeficiency Virus, and the results of epidemiological investigations were used for the analysis. The analysis made it possible to establish the main trends in the development of the epidemic process of HIV infection in the Omsk region. The general trend of decreasing morbidity has been revealed, which coincides with that in the Russian Federation, primarily due to the large volume of preventive measures carried out. Changes in the characteristics of the risk groups of infection have been established — the contingents of injecting drug users and men who have sex with men, prevailing at an early stage of the epidemic, have been replaced by persons who became sexually infected from individuals of the opposite sex. At the same time, the proportion of infected women approached that of men. This entailed the risk of perinatal transmission of HIV infection. The introduction of mandatory screening for HIV infection markers in pregnant women and the implementation of antiretroviral prophylaxis has reduced the number of cases of perinatal infection of newborns to a minimum. An increase in the share of the rural population in the total structure of newly diagnosed people with HIV infection may indicate both lower awareness of this problem and shortcomings in the provision of medical care, its lower accessibility compared to the urban population. The prevalence in the structure of HIV-infected people who are not engaged in work indicates that the most socially unprotected contingents are involved in the epidemic process, as a rule, they are not ready to take care of their own health and the health of others, often leading an antisocial lifestyle. Thus, HIV infection in the Omsk region remains one of the priority epidemiological problems requiring the formation of an integrated approach to its solution. The conducted research made it possible to identify the main risk groups for HIV infection, in relation to which targeted preventive strategies should be applied.

Criminological Characterization of Internet Fraud: Experience of the Republic of Kazakhstan

This article examines statistical data on internet fraud in the Republic of Kazakhstan from 2019 to 2023. It delves into the key demographic and social characteristics of both perpetrators and victims, identifying trends in the dynamics of internet fraud. The analysis uses statistical data to explore the age, gender, and occupational characteristics of those involved, with a focus on the most active age groups and the notably high proportion of unemployed individuals among the criminals. The authors highlight the need for improvements in law enforcement practices to better prevent internet fraud, which currently does not match the scale and dynamics of these crimes. New forms of internet fraud, such as online credit fraud and phishing—prevalent types in Kazakhstan—are discussed. The novelty of this work lies in the proposal of specific preventative measures derived from an analysis of international practices and law enforcement experiences in Kazakhstan.

Low UKA implantation volume, comorbidities, male sex, and implantation of constrained TKA are risk factors for septic revision after knee arthroplasty implantation : A register-based study from the German Arthroplasty Register

Periprosthetic joint infection (PJI) is one of the main causes of revision surgeries after total knee arthroplasty (TKA) and unicondylar knee replacement. Patient- and hospital-related risk factors must be evaluated to prevent PJI. This study identifies influencing factors and differences in infection rates between various types of implant. The basis for the data is the German Arthroplasty Register (EPRD). Septic revisions were calculated with the aid of Kaplan-Meier estimates, with septic revision surgery defined as the primary endpoint. Patients with constrained and unconstrained TKA or UKA were analysed using the Holm multiple log-rank test and the Cox proportional hazard model. The 300,998 cases of knee arthroplasty analysed included 254,144 (84.4%) unconstrained TKA, 9993 (3.3%) constrained TKA and 36,861 (12.3%) UKA, with a maximum follow-up of 7 years. After 1 year, the PJI rate was 0.5% for UKA and 2.8% for TKA, whereas after 7 years it was 4.5% for UKA and 0.9% for TKA (p < 0.0001). In constrained TKA, the PJI rate was significantly increased compared with unconstrained TKA (p < 0.0001). After 1 year, the PJI rate was 2.0% for constrained TKA and 0.8% for unconstrained TKA, as well as 3.1% and 1.4% respectively after 7 years. Implantation of a constrained TKA (HR = 2.55), male sex (HR = 1.84), an increased Elixhauser Comorbidity Index score (HR = 1.18-1.56) and an implantation volume of less than 25 UKA per year (HR = 2.15) were identified as risk factors for revision surgeries; an Elixhauser Comorbidity Index score of0 (HR = 0.80) was identified as a preventive factor. A reduced implantation volume and constrained knee arthroplasty are linked to a higher risk of PJI. Comorbidities (increased Elixhauser Comorbidity Index score), male sex and a low UKA-implantation volume were identified as risk factors for PJI. Patients who fulfil these criteria need specific infection prevention measures. Further analyses are required to investigate the potential influence of prevention and risk factor modification. III.

Parental Knowledge, Attitudes, and Utilization of Preventive Dentistry Modalities in Al Qassim, Saudi Arabia: A Cross-Sectional Study.

Background Parents play a vital role in modeling good oral hygiene practices for their children; thus, their attitude, knowledge, and awareness toward preventive dentistry can be one of the major factors contributing to children's oral health. Objectives The objective of this study is to determine the parental knowledge and attitudes toward the modalities of preventive dentistry for their children in Al Qassim, Saudi Arabia. Materials and methods A cross-sectional study was carried out using an online self-administered questionnaire designed for parents living in the Al Qassim region. The questionnaire included demographic data, parent knowledge and attitude toward preventive dentistry, and awareness of preventive dentistry procedures. The data collected were analyzed using RStudio. Results Data were collected from 392 Saudi parents (male: n = 190 (48.5%), female: n = 202 (51.5%)). The majority of participants (n = 336, 85.7%) considered the importance of primary teeth for general body health, while 320 participants (81.6%) believed that primary dentition influences permanent teeth. Awareness regarding special preventive measures like using toothpaste with fluorides comprised 87.5% (n = 343), and that of the benefits of early dental visits was 77.3% (n = 303). However, there was marked unawareness and use of preventive procedures such as serial extraction (n = 226, 57.7% of respondents unaware) and silver diamine fluoride (n = 276, 70.4% unaware). The higher levels of education and income were positively related to better knowledge and attitudes about preventive dentistry. Conclusions The current paper highlights the importance of educational interventions for enhancing parental knowledge and awareness about preventive dentistry. Community-based educational programs and increased availability of preventive dentistry services might be helpful in eliminating the knowledge gap among parents about good oral health practice.

Global burden of musculoskeletal disorders in children and adolescents from 1990 to 2021: a joint point regression and decomposition analysis.

The study aimed to investigate the pattern and trend of Musculoskeletal (MSK) disorders in people aged 5-19years from 1990 to 2021. The data was sourced from the Global Burden of Disease study 2021. The Age-standardized DALYs rates (ASDR), age-standardized mortality rate (ASMR), age-standardized prevalence rate (ASPR), and age-standardized incidence rate (ASIR) and their corresponding average annual percent change (AAPC) for MSK disorders were evaluated by sex, region, and sociodemographic index (SDI) quintiles. Globally, the ASPR of MSK disorders among children and adolescents increased per 100,000 population from 3048.66 (95% confidence interval [CI]: 2336.68-3887.02) in 1990 to 3105.46 (95% CI: 2421.09-3904.95) in 2021 (AAPC 0.06 [95% CI: 0.05-0.07]). In 2021, individuals aged 15-19 experienced the highest burden compared to those aged 5-9 and 10-14. In 2021, high SDI countries had the highest ASIR, ASPR, ASDR of MSK disorders. The AAPC of ASPR in high SDI countries showed a stark contrast to that in low SDI countries for the same period (AAPC 0.48 vs. AAPC -0.03). From 1990 to 2021, in low SDI and low-middle SDI countries, the increase in DALYs was primarily due to population growth. However, in middle SDI, high-middle, and high SDI countries, the increases were mainly due to epidemiological changes. Globally, patients aged 10-14 experienced better care compared to those in the 5-9 and 15-19 age groups. Specific preventive health measures are needed for females and adolescents aged 15-19 in high SDI countries.

Occupational Injuries of Spanish Wildland Firefighters: A Descriptive Analysis.

The work of wildland firefighters, especially of the so-called 'Brigadas de Refuerzo contra Incendios Forestales', is characterised by high physical demands and extreme operating conditions. These professionals face long workdays (12 h), walking with heavy loads (~25 kg), being exposed to high temperatures (>30 °C), and handling specialised tools in high-risk environments. This study aimed to describe the prevalence of occupational injuries among members of the 'Brigadas de Refuerzo contra Incendios Forestales' and its relationship to variables such as age and work experience. A total of 217 wildland firefighters (18 female and 199 male) correctly answered a questionnaire developed on an ad hoc basis to meet the study's objectives. A high prevalence of occupational injuries was observed among them (~76%). Age and work experience were shown to be significantly associated with injuries. Individuals over 35 years of age with more than 10 years' experience had a higher probability of injury (OR = 2.14, CI = 1.12-4.06 and OR = 2.46, CI = 1.30-4.67, respectively). Injuries occurred mainly during physical training (~46%), followed by preventive work (~33%) and forest fires (~20%). The most common injuries were tendonitis and muscle pain (~44% and ~21% respectively), followed by sprains (~21%). The results underline the need for physical activity programmes adapted to help wildland firefighters, especially older and more experienced individuals. The identification of risk factors such as age and work experience can contribute to the prevention and management of occupational injuries among this group of highly specialised forestry workers. Specific preventative measures during training are required to mitigate the risk of injury among these crews, who play a crucial role in protecting the environment and public safety.

A Protocol of Prevention and Protection Measures on New Occupational Risk Factors in Green Jobs in Italian Workplaces

The Green Transition aims to protect the health of our planet through changes at the economic, political, and social levels while also having a significant impact on the world of work through the creation of sustainable occupations, referred to as ‘Green Jobs’. The aim of our research was to identify the new emerging occupational risks associated with Green Jobs and to propose a protocol to promote the adoption of more appropriate prevention and protection measures. Starting with a few keywords chosen by the authors, we conducted a narrative review of the scientific articles published in the literature. The results obtained show that the new occupational risks emerging in the activities involved in the green transition are mainly related to the introduction of new materials or new technologies and to modes of production processes. These risks may pose a danger to those exposed to them on a daily basis, causing damage to health. Our protocol proposal calls for a more careful and adequate risk assessment for Green Jobs, providing specific training on these issues for new professionals in the sector and introducing specific prevention and protection measures for the different occupational risks analysed in the workplace. By adopting these recommendations in the workplace and conducting in-depth research on these issues, it will be possible to contribute to the improvement of prevention and protection for these new emerging occupational risks, achieving a positive economic impact and better safety conditions for workers.

Coagulation disorders in liver cirrhosis - Diagnostics and management

Patients with liver cirrhosis often exhibit complex alterations in their hemostatic system that can be associated with both bleeding and thrombotic complications. While prophylactic correction of abnormal coagulation parameters should be avoided, an individualized approach is recommended prior to invasive procedures, whereby specific preventive measures to stabilize hemostasis should be based on the periprocedural bleeding risk. While the haemostatic system of patients with compensated cirrhosis is often in a rebalanced haemostatic state due to a parallel decline in both pro- and anti-haemostatic factors, a decompensation of liver cirrhosis can lead to destabilization of this fragile equilibrium. Since conventional coagulation tests do not adequately capture the complex changes in the hemostatic system in cirrhosis, functional analysis methods such as viscoelastic tests or thrombin generation assays can be used for evaluating the coagulation status. This review describes the underlying pathophysiological changes in the hemostatic system in liver cirrhosis, provides an overview of diagnostic methods and discusses therapeutic measures in case of bleeding and thrombotic complications.

Evaluation of the risk prediction model of pressure injuries in hospitalized patient: A systematic review and meta-analysis.

The main aim of this study is to synthesize the prevalent predictive models for pressure injuries in hospitalized patients, with the goal of identifying common predictive factors linked to pressure injuries in hospitalized patients. This endeavour holds the potential to provide clinical nurses with a valuable reference for providing targeted care to high-risk patients. Pressure injuries (PIs) are a frequently occurring health problem throughout the world. There are mounting studies about risk prediction model of PIs reported and published. However, the prediction performance of the models is still unclear. Systematic review and meta-analysis: The Cochrane Library, PubMed, Embase, CINAHL, Web of Science and Chinese databases including CNKI (China National Knowledge Infrastructure), Wanfang Database, Weipu Database and CBM (China Biology Medicine). This systematic review was conducted following PRISMA recommendations. The databases of Cochrane Library, PubMed, Embase, CINAHL, Web of Science, and CNKI, Weipu Database, Wanfang Database and CBM were searched for all studies published before September 2023. We included studies with cohort, case-control designs, reporting the development of risk model and have been validated externally and internally among the hospitalized patients. Two researchers selected the retrieved studies according to the inclusion and exclusion criteria, and critically evaluated the quality of studies based on the CHARMS checklist. The PRISMA guideline was used to report the systematic review and meta-analysis. Sixty-two studies were included, which contained 99 pressure injuries risk prediction models. The AUC (area under ROC curve) of modelling in 32 prediction models were reported ranged from .70 to .99, while the AUC of verification in 38 models were reported ranged from .70 to .98. Gender (OR = 1.41, CI: .99 ~ 1.31), age (WMD = 8.81, CI: 8.11 ~ 9.57), diabetes mellitus (OR = 1.64, CI: 1.36 ~ 1.99), mechanical ventilation (OR = 2.71, CI: 2.05 ~ 3.57), length of hospital stay (WMD = 7.65, CI: 7.24 ~ 8.05) were the most common predictors of pressure injuries. Studies of PIs risk prediction model in hospitalized patients had high research quality, and the risk prediction models also had good predictive performance. However, some of the included studies lacked of internal or external validation in modelling, which affected the stability and extendibility. The aged, male patient in ICU, albumin, haematocrit, low haemoglobin level, diabetes, mechanical ventilation and length of stay in hospital were high-risk factors for pressure injuries in hospitalized patients. In the future, it is recommended that clinical nurses, in practice, select predictive models with better performance to identify high-risk patients based on the actual situation and provide care targeting the high-risk factors to prevent the occurrence of diseases. The risk prediction model is an effective tool for identifying patients at the risk of developing PIs. With the help of risk prediction tool, nurses can identify the high-risk patients and common predictive factors, predict the probability of developing PIs, then provide specific preventive measures to improve the outcomes of these patients. CRD42023445258.