Specific Hazards Research Articles

The need for general adaptive capacity-Discussing resilience with complex adaptive systems theory.

The concept of resilience intrinsically links with both complexity and adaptive capacity. Scholars from different fields agree on this. Still, the detailed relations between resilience, complexity, and adaptive capacity need a more thorough theoretical analysis. This article analyses resilience with the help of assumptions from complex adaptive systems (CAS) theory to answer two questions in more detail: What is the relation between resilience and complexity? How can adaptive capacity contribute to resilience? By applying basic ideas from CAS theory to the resilience discourse, the article deduces that complexity of a system is a necessary condition for resilience because complex systems consist of agents that possess adaptive capacity, whereas simple systems consist of mere elements that cannot adapt to unexpected disruptions. The relation between complexity and resilience is multidimensional. Growing complexity leads to a growing need for resilience because the chances for severe, unexpected disruptions increase. The analysis of adaptive capacities revealed that systems and the agents they consist of can possess of specialized and general adaptive capacity. General adaptive capacity is the core feature of resilience because it enables systems to cope with unexpected disruptions. System design principles such as diversity within functional groups and redundancy help to increase general adaptive capacity. The same is true on the community level for social capital and on the individual level for disaster preparedness measures because they increase coping capacities independent of specific hazards.

Natural Hazards and Climate Change Impacts on Food Security and Rural–Urban Livelihoods in Mozambique—A Bibliometric Analysis and Framework

Mozambique is confronted with numerous risks related to food security and natural disasters. The study conducted a literature review on natural hazards and food security. This can help to identify gaps and further areas of research. A bibliometric analysis was conducted using standardized text search terms, and the VOSviewer tool was used to analyze over 7000 scientific articles and cluster over 60,000 keyword co-occurrences. The results show that research on natural hazards for food security needs to be integrated. The priority topic of disasters focuses on specific hazards such as climate change, floods, and hurricanes, which are also linked to demographic and other social variables. More studies on food security, such as droughts, sustainable development, and other human and social conditions, are being conducted. Resilience as an emerging research paradigm needs to be addressed in comparison. One result is an analytical framework on impacts on food security in the context of disaster risk, based on the empirical findings of the literature review. It shows how everyday risks such as disease or food security can be conceptually better linked to natural hazards and resilience. It shows that further research is needed on the interlinkages of multiple risks, of which Mozambique is an outstanding example. The methodology presented is also applied to provide a framework for linking multiple risks to food security and natural hazards. The innovative dimension of the research is that this inquiry constitutes one of the pioneering attempts to conduct a bibliometric analysis of the linkages between natural hazards, food security, and resilience in Mozambique. Another noteworthy contribution is introducing a novel analytical framework that integrates food security and disaster risks.

Data‐driven machine learning for multi‐hazard fragility surfaces in seismic resilience analysis

AbstractOffshore earthquakes and subsequent tsunamis pose significant risks to many coastal populations worldwide. This paper introduces a data‐driven machine learning model that synthesizes accurate 3D earthquake–tsunami fragility surfaces from randomly selected 2D fragility curves. The integration of physics‐based simulations enhances the model's reliability for these specific hazards, making it a valuable tool for multi‐hazard analysis in earthquake–tsunami contexts. Additionally, by shifting 2D fragility curves to represent retrofitted structural systems, the model can generate earthquake–tsunami fragility surfaces for community‐level mitigation studies. While the model is demonstrated for earthquake–tsunami scenarios, its methodology architecture has the potential to contribute to other multi‐hazard situations for the initial conditions in multi‐hazard community resilience analysis.

Molybdenum doping leads to faster photo-dissolution of commercial molybdate red pigment than chrome yellow pigment under sunlight irradiation

The photo-dissolution of lead chromate pigments poses specific environmental hazards. In this study, we report that doping molybdenum in lead chromate pigments, resulting in commonly known molybdate red pigment, increases the risk of heavy metal leaching when exposed to light. Commercial molybdate red pigments undergo photo-dissolution when exposed to simulated sunlight and exhibit lower photostability compared to lead chromate pigments such as chrome yellow. After 24 h of irradiation, the leaching rates of toxic lead and chromium from molybdate red pigments were 2.98 and 3.70 times higher, respectively, than those from chrome yellow pigments. The primary factor leading to decreased pigment photostability is the activation of pigment semiconductors facilitated by molybdenum doping. Molybdate red pigments exhibit a broader light absorption spectrum and more efficient separation and transfer of photogenerated charge carriers than chrome yellow pigments, boosting the photochemical activity. To the best of our knowledge, this is the first study to illustrate the doping effect on the photostability of commercial inorganic pigments and the consequent heavy metal leaching. Our results suggest that Mo doping reduces the photostability of lead chromate pigments, highlighting the potential elevated environmental risks associated with complex inorganic pigments.

Ergonomic challenges of mortuary attendants in Ghana: an exploratory study

Objective. Mortuary attendants in Ghana face various occupational health and safety hazards, including ergonomic and psychosocial factors, which can impact both their well-being and the quality of service provided. However, there is limited knowledge about the specific ergonomic hazards they encounter. This study aims to investigate and understand these ergonomic hazards at selected hospital mortuaries in Ghana. Methods. The study used a qualitative approach to investigate the experiences of 19 mortuary attendants, selected through purposive sampling. Semi-structured interviews were conducted and recorded digitally, and focused on participants’ demographics, work experiences, challenges and coping strategies. The collected data were transcribed verbatim and analyzed thematically. Results. The study found that mortuary attendants face ergonomic hazards, leading to physical discomfort, sleep problems and the need for sick leave and self-medication. Poor working conditions were a major risk factor. Conclusion. The study recommends the immediate inclusion of fundamental occupational health and safety practices into the informal apprenticeship training for mortuary attendants. Additionally, the study underscores the importance of providing necessary equipment to mortuary attendants to reduce or eliminate ergonomic hazards in their work environments.

Progress in toxicogenomics to protect human health.

Toxicogenomics measures molecular features, such as transcripts, proteins, metabolites and epigenomic modifications, to understand and predict the toxicological effects of environmental and pharmaceutical exposures. Transcriptomics has become an integral tool in contemporary toxicology research owing to innovations in gene expression profiling that can provide mechanistic and quantitative information at scale. These data can be used to predict toxicological hazards through the use of transcriptomic biomarkers, network inference analyses, pattern-matching approaches and artificial intelligence. Furthermore, emerging approaches, such as high-throughput dose-response modelling, can leverage toxicogenomic data for human health protection even in the absence of predicting specific hazards. Finally, single-cell transcriptomics and multi-omics provide detailed insights into toxicological mechanisms. Here, we review the progress since the inception of toxicogenomics in applying transcriptomics towards toxicology testing and highlight advances that are transforming risk assessment.

Simultaneous determination of phenothiazine drugs and their metabolites residues in animal derived foods by high performance liquid chromatography tandem mass spectrometry

Due to their potential entry into the human body via the food chain, phenothiazine drugs and their metabolites pose specific health hazards, making their detection in edible tissues of paramount importance. In this research endeavor, a highly sensitive multi-residue analytical method has been devised for the detection of phenothiazine drugs and their metabolites in animal-derived food products, utilizing high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS). The preparation of samples involved the use of 1% formic acid in acetonitrile as the extraction solvent following sample weighing, with multiple extraction steps diligently performed to ensure optimal outcomes. The sample, post-extraction, was directly introduced into the purification column, yielding significant time savings and rendering the process more environmentally sustainable. This procedural step effectively eliminated interfering substances from the sample matrix, including proteins, salts, and phospholipids. Analysis of the extracted samples was conducted through HPLC-MS/MS, employing an electrospray ionization (ESI) ion source. A comprehensive panel of 20 phenothiazine drugs and their metabolites was successfully resolved within a mere 10-min chromatographic run. A robust linear correlation (R2 ≥ 0.99) was attained within a judiciously chosen range of concentrations. Method validation was meticulously conducted across multiple animal species, including trout, white shrimp, pork, beef and chicken. The developed analytical method has been effectively deployed for the screening and quantification of phenothiazine drugs in real-world samples sourced from commercial livestock and aquatic products.

Safety impacts of design for manufacture and assembly techniques in off-site construction

Design for manufacture and assembly (DfMA) is an approach for improving project safety performance. For off-site construction (OSC), the philosophy is increasingly becoming a preferred design approach for OSC components. However, studies examining the safety impact of DfMA in OSC are limited. This study investigated the potential effects of DfMA techniques on mitigating specific safety hazards in OSC. A literature review identified and paired DfMA techniques and the safety hazards they mitigate. Empirical data was collected using a survey to assess the identified relationships. Data was analyzed using a combination of frequencies, inferential statistics, and Cronbach’s alpha. Most respondents agreed that DfMA techniques control their pairwise safety hazards in OSC. To eliminate safety hazards and limit their socio-economic impact, contracting organisations engaged in OSC need to consider the application of DfMA in the manufacture, assembly, and disassembly processes of OSC. The study reaffirms the importance of implementing evidence-based DfMA techniques for mitigating safety hazards in developing countries where OSC is an emerging philosophy.

Understanding Home Safety Concerns for Adolescents With Brain Injuries: An Evaluation of Hazards, Risks, & Harms

Abstract Date Presented 03/23/24 Adolescents with acquired brain injury (ABI) are at risk for additional injury, but little is known about specific home safety hazards. This research examines stakeholder perceptions of pre- and self-identified home safety hazards, risks, and harms for this population. Primary Author and Speaker: Sarah E. Anderson Contributing Authors: Taylor Stamper, Sarah Pierce, Jennifer P. Lundine, Carmen DiGiovine, Emily Patterson, Scott Swearingen, Lauren Wengerd, Amy Darragh

Overcoming Barriers and Fostering Adoption: Evaluating the Institutional Mainstreaming of Nature-Based Solutions in the Emilia-Romagna Region’s Socio-Ecological System

International organizations like the EU and IUCN are advocating for nature-based solutions (NBSs) as green alternatives for climate change adaptation and mitigation, especially in disaster risk reduction and urban planning. The H2020 OPERANDUM project was designed to address the major hydro-meteorological risks (floods, droughts, landslides, storm surge, and coastal erosions) through the deployment and assessment of NBSs in different contexts and areas affected by specific hazards. Despite growing research and funding, NBSs are still in the early stages of mainstream adoption and face challenges in acceptance and dissemination. Although designed to benefit both social and ecological systems, they remain a niche area with low perceived effectiveness among technicians and decision-makers. Their uptake requires a paradigm shift that includes a change in cultural-cognitive institutions, a different and wider set of knowledge than traditional engineering (ecological, social), and an adaptive management approach, missing within the current governance system. Using a qualitative case study research method, this paper aims to identify barriers in mainstreaming NBSs for DRR (disaster risk reduction) in the Emilia-Romagna region—influenced not only by individual beliefs but also by variables tied to technical culture and local procedural norms—and emphasizing the importance of combining social and ecological indicators in socio-ecological system analysis.

External Hazard Analysis for Water-Based Nuclear Power Plants

Based on recent studies, Water-Based Nuclear Power Plants (NPPs) include onshore and offshore floating NPPs, gravity-based structure NPPs, and underwater NPPs. These NPPs are increasingly considered for their benefits, such as the floating NPPs ability to distribute energy to remote areas, offshore sites, and construction activities. Regarding safety, external hazards must be considered during the design phase as stated in the Head of Nuclear Energy Regulatory Agency Regulation Number 3 Year 2011 and Specific Safety Requirements-2/1 (Rev 1). The external hazards of Water- Based NPPs should differ from those of land-based NPPs. Several studies have outlined the external hazards that water-based NPPs only address, such as onshore floating NPPs, and have yet to discuss the impact on water-based NPPs' safety. This study reviews the external hazards that must be considered and their effects on all types of Water-Based NPPs. The study is conducted by reviewing national regulations and international references to identify specific external hazards for Water-Based NPPs, followed by examining scientific works related to marine safety and Water-Based NPP design information to understand the impact of external hazards on the facilities. The review indicates that the external hazards that need to be considered for Water-Based NPPs include weather hazards, human- induced external hazards, earthquakes, and tsunamis. Keywords: NPP, Floating NPP, External Hazard, nuclear safety

Lactating exposure to microplastics at the dose of infants ingested during artificial feeding induced reproductive toxicity in female mice and their offspring

Microplastics (MPs) pollution poses a global environmental challenge with significant concerns regarding its potential impact on human health. Toxicological investigations have revealed multi-system impairments caused by MPs in various organisms. However, the specific reproductive hazards in human contexts remain elusive, and understanding the transgenerational reproductive toxicity of MPs remains limited. This study delves into the reproductive toxicity resulting from lactational exposure to polystyrene MPs (PS-MPs) in female mice, extending the inquiry to assess the reproductive effects on their offspring bred by rigorous natural mating. The MPs dosage corresponds to the detected concentration in infant formula prepared using plastic bottles. By systematically evaluating the reproductive phenotypes of F0 female mice from birth to adulthood, we found that female mice exposed to PS-MPs exhibited delayed puberty, disturbed estrous cyclicity, diminished fertility, elevated testosterone, abnormal follicle development, disrupted ovarian steroidogenesis, and ovarian inflammation. Importantly, the observed inheritable reproductive toxicity manifested with gender specificity, showcasing more pronounced abnormalities in male offspring. Specifically, reproductive disorders did not manifest in female offspring; however, a significant decrease in sperm count and viability was observed in PS-MPs-exposed F1 males. Testicular transcriptomics analysis of F1 males significantly enriched pathways associated with reproductive system development and epigenetic modification, such as male germ cell proliferation, DNA methylation, and histone modification. In summary, real-life exposure to PS-MPs impaired the reproductive function of female mice and threateningly disrupted the spermatogenesis of their F1 male offspring, which raises serious concerns about inter- and trans-generational reproductive toxicities of MPs in mammals. These findings underscore the potential threats of MPs to human reproductive health, emphasizing the need for continued vigilance and research in this critical area.

A semi-quantitative multi-hazard risk assessment framework for European coastal urban areas

Coastal cities are increasingly exposed to a wide range of hydro-meteorological and climate-related hazards and their negative consequences. Developing disaster risk assessments to support risk management activities in these areas is therefore a critically important but challenging task, due to the diversity of processes involved and associated data requirements. Semi-quantitative, i.e. index-based assessments can be instrumental in addressing these issues: by trading off some detail in the representation of risk for simplicity in the underlying data and methods, it becomes possible to assess, compare, and easily communicate risk for various sectors, hazards, and locations. In this context, the present article presents a new semi-quantitative, GIS-based multi-hazard risk assessment framework for coastal urban areas. The framework uses various large-scale datasets and state-of-the-art risk modelling concepts to provide risk scores for six perils in European coastal cities: fluvial flooding, coastal flooding, extreme precipitation, landslide, heat wave, and coastal erosion. An application is presented for the risk assessment of ten case-study areas, illustrating the potential of the proposed framework for identifying the most pressing risks for each area and supporting the prioritization of more detailed quantitative risk assessments for specific cities, sectors and/or hazards, based on which risk mitigation measures can be defined.

Systematic risk ranking of microbiological hazards in infant foods

Ensuring food safety, particularly for vulnerable groups, like infants and young children, requires identifying and prioritizing potential hazards in food chains. We previously developed a web-based decision support system (DSS) to identify specific microbiological hazards (MHs) in infant and toddler foods through a structured five-step process. This study takes the framework further by introducing systematic risk ranking (RR) steps to rank MH risks with seven criteria: process survival, recontamination, growth opportunity, meal preparation, hazard-food association evidence, food consumption habits of infants and toddlers in the EU, and MH severity. Each criterion is given a semi-quantitative or quantitative score or risk value, contributing to the final MH risk calculation via three aggregation methods: semi-quantitative risk scoring, semi-quantitative risk value, and outranking multi-criteria decision analysis (MCDA). To validate the criteria and ranking approaches, we conducted a case study to rank MH risks in infant formula, compared the results of the three risk ranking methods, and additionally evaluated the ranking results against expert opinions to ensure their accuracy. The results showed strong agreement among the three methods, consistently ranking Salmonella non-Typhi and Cronobacter spp. and Shiga-toxin-producing Escherichia coli as the top MH risks in infant formulae, with minor deviations. When MHs were ranked after an initial hazard identification step, all three methods produced nearly identical MH rankings, reinforcing the reliability of the ranking steps and the selected criteria. Notably, the risk value and MCDA methods provided more informative MH rankings compared to the risk scoring method. The risk value and risk scoring methods were implemented into an online tool, called the MIcrobiological hazards risk RAnking decision support system (Mira-DSS), available at https://foodmicrobiologywur.shinyapps.io/MIcrobial_hazards_RAnking/. In conclusion, our framework enables the ranking of MH risks, facilitating intervention comparisons and resource allocations to mitigate MH risks in infant foods, with potential applicability to broader food categories.

Readability and Suitability of Local Disaster Preparedness Materials in Predominantly Hispanic Border Communities: A Case Study of Cameron County, Texas

Abstract Community awareness is a key component of disaster resilience and numerous agencies developed a plethora of preparedness materials. Previous studies evaluated national-level resources and social media content indicating that these efforts are not effectively reaching vulnerable populations, as the information is provided at or above the secondary education level. However, the local-specific content has been mostly overlooked in the analyses, subsequently neglecting the needs of areas with specific demographics and hazards, like predominantly Hispanic border communities. Thus, this study turns to local preparedness and mitigation materials, rather than general internet searches or national level documents. We analyze information provided on 239 webpages of local authorities in Cameron county in the southernmost tip of Texas. We evaluate: 1) the availability of languages and visual materials, 2) the reading difficulty level, and 3) the suitability of content. Our results demonstrate the lack of suitable and readable information provided on the local authorities’ websites with the average readability level implying “difficult” to “very confusing”, and the average suitability score equivalent to “below average/adequate”. Moreover, the lack of Spanish-language content indicates an under-utilization of the otherwise vernacular language. We discuss those results in the socio-cultural context of the border community.

A qualitative exploration of e-cigarette prevention advertisements' effectiveness among college students in China.

The rapid growth of e-cigarette usage among youth and young people has emerged as a significant public health concern. It is imperative to initiate effective vaping prevention campaigns and undertake relevant research to address this pressing issue. This research seeks to identify effective video advertisements to deter young people from starting to use e-cigarettes. It aims to offer evidence-based insights and recommendations for creating communication materials and designing messages for youth e-cigarette prevention efforts. College students aged 18-24 years (n=40) participated in focus groups within this qualitative study. After viewing four stimulus videos, participants discussed what they perceived as effective and ineffective video characteristics, as well as suggestions for future videos. Effective video characteristics included the use of real-life testimonials, displaying specific health hazards, revealing harmful chemical ingredients and the deceptive nature of flavors, and positively perceived effectiveness. Participants generally found that videos with strong visual impact and graphics were more engaging and that approaches using fear and emotion were more effective. Ineffective characteristics included complex and exaggerated information, lack of empathy and irrelevance, insufficiently specific information, extreme and death-themed content, industry messages, as well as preachy tones, animations, metaphors, dull formats, excessive length, and scenes of e-cigarette use. Developing anti-e-cigarette campaign materials for youth necessitates target audience-focused qualitative research. This helps in deeply exploring and identifying effective themes and messages, as well as video characteristics and details while avoiding ineffective or even misleading messages and themes from young people's perspectives outside the United States. Future development of e-cigarette prevention videos for Chinese college students may consider incorporating localized real-life testimonial cases to convey specific harms, including self-efficacy information, and utilizing fear and emotional appeals.

Understanding the dynamic process of human behavior changes towards disaster preparedness: An application of the integrated TTM with SCT and PMT

Integrating the Transtheoretical Model with Social Cognitive Theory and Protection Motivation Theory, we propose a new model to study the progress of behavior changes towards disaster preparedness along three developmental stages: from “not prepared” (NP), to “intention to prepare” (IP), to “already prepared” (AP). Using the 2021 National Household Survey data (FEMA, N = 6,180), we tested this model by employing a series of nested weighted generalized ordered logistic regressions. We found that, although Hispanics have a larger prevalence of IP than their non-Hispanic white counterparts, they are less likely to move to the AP stage. The observed ethnic disparity is largely due to the disparities in actual behavioral capabilities in essential knowledge and access to resources between the two groups. Personal disaster experience, social/observational learning, self-efficacy, and risk perception each facilitate behavior changes from the NP to IP or AP stage (i.e., departure from NP stage) and from NP or IP stage to AP stage (i.e., arrival at AP stage). Although income does not necessarily influence one's decision to depart from the NP stage, it determines one's arrival at the AP stage. Increasing one's income further boosts the realization of AP for people with high-risk perceptions. However, for people with moderate or low levels of risk perceptions, increased income did not lead to arrival at the AP stage. Additional research is needed to more fully apply this process-oriented approach with new measurement introduced in this paper to study the behavior changes among subpopulations in exposure to specific hazards.

A comparison of periodic health examinations and workplace health screening for workers in Singapore and Japan.

This article aims to provide a historical overview of how workplace safety and health legislations in Singapore and Japan have evolved, and perform a comparative analysis of the occupational health systems where work-related medical examinations and health screening are concerned. The discourse is centered on three key themes - coverage, comprehensiveness, and continuity of care. The comparative analysis was performed based on secondary data obtained from open-source platforms. Singapore and Japan have robust workplace safety and health legislative frameworks and laws. However, their approaches diverge because of differing socioeconomic and political contexts. Japan's regulations are generally more comprehensive, require more frequent monitoring of workers' health status, and encompass both physical and mental health components. Singaporean companies focus primarily on the physical component of health, and statutory examinations are required only for exposure to specific occupational hazards. With increasing prominence of mental health issues and shift towards preventive care in Singapore, there will be greater emphasis on a holistic approach to each employee's overall health in future. For Japan, the challenge would be to strike a balance between long-term sustainability of current policies against the need for state and corporations to still retain an adequate stake in ensuring workers' overall health.

The clinical effectiveness of Fidaxomicin compared to Vancomycin in the treatment of Clostridioides difficile infection, a single center real-world experience.

The use of fidaxomicin is recommended as first line therapy for all patients with Clostridioides difficile infection (CDI). However, real-world studies have shown conflicting evidence of superiority. We conducted a retrospective single center study of patients diagnosed with CDI between 2011-2021. A primary composite outcome of clinical failure, 30-day relapse or CDI-related death was used. A multivariable cause specific Cox proportional hazards model was used to evaluate fidaxomicin compared to vancomycin in preventing the composite outcome. A separate model was fit on a subset of patients with C. difficile ribotypes adjusting for ribotype. There were 598 patients included, of whom 84 received fidaxomicin. The primary outcome occurred in 8 (9.5%) in the fidaxomicin group compared to 111 (21.6%) in the vancomycin group. The adjusted multivariable model showed fidaxomicin was associated with 63% reduction in the risk of the composite outcome compared to vancomycin (HR = 0.37, 95% CI 0.17-0.80). In the 337 patients with ribotype data after adjusting for ribotype 027, the results showing superiority of fidaxomicin were maintained (HR = 0.19, 95% CI 0.05-0.77). In the treatment of CDI, we showed that real-world use of fidaxomicin is associated with lower risk of a composite endpoint of treatment failure.

Delimitation and Prioritization of Climate-Affected Areas Using the Example of a Post-Industrial City

This study adapted and tested an approach to identifying areas that are particularly vulnerable to climate-related hazards using the example of the post-industrial city of Knurów in Poland. This study applied a multi-criteria method using the analytical hierarchy process based on GIS map data. The analysis was divided into statistical regions defined for the city. Fifteen attributes were defined for each statistical region. The applied methods provided verified spatial information related to specific climate change hazards. The results showed that the most vulnerable areas were the areas with intensive development in the city center and in the southwestern part of the city. Among the 15 attributes, the most significant were T1 (number of inhabitants in zones with a higher potential thermal risk index by statistical district) with a value of 0.163, G2 (percentage of the sum of tree-shaded areas in built-up areas within the territory of a given statistical district) with 0.143 and H3 (number of buildings in areas of drainless basins and 100-year water). This method effectively identified the most vulnerable areas. The use of such a method can help in the preparation of planning documents and urban adaptation plans by determining the thermally and hydrologically vulnerable areas with the least developed green infrastructure as an exposure-mitigating factor.