Due to the increase in cancer cases worldwide, natural products are gaining interest, particularlythose herb-based extractsare growing. Plants are classified as one of the primary suppliers of bioactive components. The species Solidago Canadensis, Asterales, Asteraceae, and Plantae are found in Iraq. The upper parts of these plants are very often utilized to treat inflammatory disorders. S. Canadensis L. has been extracted as phytochemical compounds for anti-colorectal adenocarcinoma and -acute monocytic leukemia (AML) in in-vivo cancer models to find novel sources of the anticancer mixture.The relationship between each investigation is one of the critical phases for the effects associated with this particular style of study. In the present research, extracted phytochemical compounds from S. Canadensis L. were discovered to significantly inhibit colorectal adenocarcinoma and AML in vitro, and the narrative makes this compound promising for antitumor activity testing in vivo.