Mushroom Species Research Articles

Comparison of the effect of UVB application on the antioxidant properties of different mushroom species with vitamins D2 and D3

Comparison of the effect of UVB application on the antioxidant properties of different mushroom species with vitamins D2 and D3

Wild mushrooms

This article presents the uses, consumption practices, and popular beliefs related to wild mushrooms in Europe and Siberia from the Neolithic period to the present day. First, we will introduce various saproxylic mushrooms used for starting fires, as well as the medicinal uses of some species. Then, we will describe the gathering and consumption practices of edible wild mushrooms in Europe and Siberia. These consumption practices, varying by culture, region, and time period, will be specified for six edible species. Finally, we will address popular beliefs and the magical-religious rituals associated with some mushroom species.

PREPARATION OF PLEUROTUS SPAWN ON DIFFERENT GRAIN SUBSTRATES

The cultivation of Pleurotus is gaining momentum due to its nutritional value and economic potential. The preparation of mushroom spawn on grain media involves inoculating them with pure cultures of certain mushroom species under sterile conditions, yet contamination of the spawn is a significant barrier to the growth and spread of mushroom farming in underdeveloped nations. In this study, the spawn growth of Pleurotus species on various grain substrates including maize, wheat, sorghum and bajra was explored. The results revealed significant differences in spawn growth duration among the substrates. Maize substrate exhibited the longest duration for spawn growth, requiring 19 days, while wheat, sorghum and bajra substrates displayed shorter duration of 15, 10 and 11 days respectively. Furthermore, each substrate demonstrated distinct characteristics influencing spawn growth, highlighting the importance of substrate selection in Pleurotus species cultivation. These finding provide valuable insights for optimizing spawn production process and enhancing the efficiency of Pleurotus species cultivation practices.

Exploring the Antioxidant Potential of Methanolic Extracts of Wild Medicinal and Edible Mushrooms from Darma Valley, Pithoragaph, Kumaun (Himalaya, India).

This study presents a comprehensive analysis of the methanolic extracts of nine species of wild edible mushrooms (WEM) native to the Darma Valley in the Kumaun Himalaya region. The investigation encompasses the assessment of various biochemical attributes, including total phenolics (TP), total flavonoids (TF), total tannins (TT) contents, the ABTS assay, and the DPPH radical scavenging assay. Among the nine WEM species examined, Clavatia craniiformis stands out for displaying the highest antioxidant capacities, indicated by exceptional TP (54.94 ± 0.54 mg gallic acid equivalenta/g dry weight) and TT (4.23 ± 0.17 mg tannic acid equivalents/g dry weight) contents, along with noteworthy ABTS (10.44 ± 0.34 mg abscorbic acid equivalents/g dw) and DPPH activity (0.335 ± 0.001 mg abscorbic acid equivalents/g dry weight). Subsequent antioxidant potential are mushrooms Ramaria fennica, Ramaria botrytis, Ramaria sanguinea, Ramaria flava, Gomphus. clavatus, Clavaria zollingeri, Pleurotus ostreatus, and Kuehneromyces mutabilis. Variations in antioxidant capacities align with distinct phenolic content. This study underscores as a remarkable source of antioxidants, suggesting its potential suitability for nutraceutical applications. The findings contribute to a deeper understanding of the antioxidant properties inherent in wild edible mushrooms, particularly emphasizing the prominence of C. craniiformis.

Two Photosensitive Dermatitis Outbreaks Caused by Cordierites frondosus - Chuxiong Yi Autonomous Prefecture, Yunnan Province, China, 2023.

Cordierites frondosus (C. frondosus) is a species of toxic mushroom known to induce symptoms of photosensitive dermatitis. In the months of May and June 2023, a total of four patients in Chuxiong Yi Autonomous Prefecture, Yunnan Province, were affected by C. frondosus poisoning, occurring over two distinct incidents. The condition of two patients deteriorated after they were re-exposed to sunlight on the seventh day following the initial poisoning. Separately, an additional two patients reported experiencing a mild, needle-like sensation on areas of their skin exposed to the sun, recorded on the twelfth day subsequent to the poisoning. Given that symptoms of photosensitive dermatitis, a potential severe consequence of C. frondosus poisoning, can manifest up to a week post-sun exposure, it is advisable to avoid sunlight for a minimum of two weeks following poisoning.

EFFECT OF ORGANIC SUBSTRATES ON THE INVASION PARAMETERS OF THE CULTIVATION OF THREE TYPES OF OYSTER MUSHROOMS IN CÔTE D’IVOIRE

Accelerated deforestation of the vegetation cover combined with climate change is influencing the seasonal availability of carpophores in different regions of the country. This study aims to improve mushroom production in Côte d'Ivoire through the use of different types of organic substrates. The methodology consisted in using three types of oyster mushroom (Pleurotus cornucopiae, Pleurotus ostreatus and Pleurotus citrinopileatus) subjected to different types of organic substrates (sawdust and banana leaves) in a split-plot system in which three treatments (Sb, Sc and Fb) compared with a control (Sa) were stored in a dark chamber until the culture bags were fully invaded, in order to determine the percentage, height, speed and volume of substrates colonized. The results showed that the different oyster mushroom species significantly influenced all invasion parameters (P=0.00***), unlike the different substrates (P=0.59) considered. Similarly, species-substrate interaction had a significant effect on the evolution of the different oyster mushroom species. This study shows that the evolution of the invasion parameters of oyster mushroom cultivation, particularly that of Pleurotus cornucopiae, had a good mycelial development on the various substrates and can therefore be integrated into the production circuit in Côte d'Ivoire.

Wild mushrooms: A Source of livelihood and future urban food

Wild edible mushrooms are more popular non timber forest products (NTFPs) which are highly valued as functional food for their medicinal and nutritional benefits. Several wild mushroom species have been pointed out as sources of bioactive compounds, in addition to their important nutritional value. They are the major source of income for the indigenous communities throughout the world. In Bonai Forest Division, Sundargarh, Odisha, survey was conducted during 2021 to 2022 with informants using semistructured interviews and gathered the information about the wild edible mushrooms available in their forest with their marketability. It was observed that the mushrooms play as an excellent source of livelihood for local communities in Bonai Forest Division and these mushrooms are sold in the local markets starting from 10- 20 rupees to 400 rupees. Therefore, the wild edible mushrooms which are available in the state need more exploration. It could be a valuable nutraceutical, making them essential in combating food insecurity. Additional research is needed so that the wild edible mushrooms can be commercialized which can play a key role in the socio-economic upliftment of the tribal people and will add organic food to the urban food basket.

Diversity and Ethno-Mycopharmacological Insights of Medicinal Mushrooms of the Bangus Valley of Jammu and Kashmir, India.

The present study was carried out in various regions of Jammu and Kashmir, India, for the diversity and pharmacology of wild mushrooms. The valley is bestowed with alpine meadows and dense coniferous forest. Because of its isolation, security concerns, and line of control, most of these locations either have been little investigated or are entirely undiscovered. During the intensive survey of various locations, 20 mushroom species were collected from the surveyed areas. The ethno-mycological information was gathered from tribal communities and local herbalists (hakims). It was observed that 16 species were used against cold, constipation, liver and skin disorders, digestion problems, wound healing, and the like. However, these medicinal mushrooms are losing their relevance, so there is an urgent need to explore and preserve this knowledge for future use as medicine.

Antioxidative and Antibacterial Hydro-Ethanolic Fraction from an Asian Edible Mushroom Lentinus sajor-caju (Agaricomycetes) Suppresses Inflammatory Responses by Downregulating COX-2 and iNOS Expression.

Mushrooms are prevalently important sources of pharmaceutically active metabolites. Various mushroom species belonging to the Lentinus genus are recognized for their nutritional and therapeutic properties. One such species is L. sajor-caju, which is renowned in Southeast Asian nations for its culinary value. The primary goal of this study is to investigate the potential medicinal properties of L. sajor-caju, specifically its antioxidant, antibacterial, and anti-inflammatory effects. A hydroethanolic extract was formulated using dried basidiocarps, which exhibited a high phenolic content of approximately 14% and a flavonoid content of approximately 2.7%. The extract demonstrated significant antioxidant potential in in vitro reactions. The extract is sufficiently capable of scavenging free radicals (DPPH and ABTS) and chelate Fe2+ with EC50 values spanning from 186 to 390 μg/mL. In addition, considerable antimicrobial activity against tested pathogenic microorganisms was observed, as indicated by low MIC50 values (256-358 μg/mL). Moreover, the fraction was found to prevent heat-induced protein denaturation which signifies its anti-inflammatory potential. When tested on the RAW 264.7 cell line, reduction in the nitrite production, and downregulation of COX-2 and iNOS mRNA expression was observed which are the key regulator of inflammatory signalling systems. The study, therefore, recommends the use of L. sajor-caju in the medical and pharmaceutical industries for the benefit of humanity.

Exploring the Functional Properties and Nutritional Values of Colored Oyster Mushrooms Species (Pleurotus, Agaricomycetes): A Review.

Colored oyster mushrooms species of genus Pleurotus are a variety of edible mushrooms that attract a lot of interest among the consumers and scientists due to its scientific evidence that they have promising health benefits. However, information on their characteristics and properties is still scarce. Consequently, it is important to determine the potential health benefits of the mushrooms. This review paper presents an overview of functional properties and nutritional values of colored oyster mushrooms (Pleurotus spp.). It particularly discusses the types of pigments present in Pleurotus spp., their characteristics, and potential nutritional values. Pigments such as melanin, carotenoids, and flavonoids are reported to be present in colored oyster mushrooms. Moreover, the antioxidant compounds of these mushrooms have been unveiled, demonstrating their potential to counteract oxidative stress and improve general health. In addition, the investigation into the nutritional characteristics of the mushrooms reveals encouraging aspects for their incorporation into dietary considerations. Thus, it can be concluded that colored Pleurotus species have an immense amount of potential for use as natural colorants, as well as nutritious and antioxidant-rich compounds. These mushrooms represent an important advancement in the search for functional foods due to their significant nutrients such as proteins, amino acids, carbohydrates, and fibers.

Potencial inibitório de extratos bioativos de cogumelos do sul do Brasil sobre o oomiceto patogênico Pythium insidiosum

ABSTRACT: Pythium insidiosum is an important oomycete pathogen of mammals that causes pythiosis, an endemic disease in warm climates that stands out for its unfavorable prognosis, lethality in the affected species, and difficulties in treatment. This study evaluated in vitro anti-P. insidiosum potential of aqueous, hydroethanolic, and ethanolic extracts of indigenous wild mushrooms from southern Brazil. The extracts were prepared from Amanita gemmata, Amanita muscaria, Auricularia auricula, Gymnopilus junonius, Lactarius deliciosus, Laccaria laccata, Psilocybe cubensis, and Russula xerampelina. In vitro susceptibility assays employed the microdilution technique according to the M38-A2 protocol CLSI. The hydroethanolic and ethanolic extracts of R. xerampelina showed anti-P. insidiosum activity at minimum inhibitory concentrations ranging from 1.87-7.50 mg/mL. The other mushroom species extracts showed no inhibitory effects on growth of P. insidiosum. This is the first study to evaluate the antimicrobial activity of mushrooms on oomycetes, evidencing the antimicrobial potential of R. xerampelina on the pathogen P. insidiosum. So, the present study expands new perspectives, since the secondary metabolites produced by mushrooms can be potential targets for the development of new categories of medicines. However, considering the wide biodiversity of Brazilian mushrooms, we suggested that the search for other basidiomycetes species with anti-P. insidiosum action needs to be expanded.

FATTY ACID COMPOSITION OF FIVE MUSHROOM SPECIES BY GC AND GC-MS WITH A CHEMOMETRIC APPROACH

Fatty acids are recognized as energy sources and membrane components. The biological effects of the fatty acids are composed of influencing cell and tissue metabolism, and responding to hormonal and other signals. This study was planned to characterize the fatty acid compositions of five different mushrooms namely, Cerrena unicolor, Hymenochaete rubiginosa, Inocutis rheades, Leptoporus mollis, and Polyporus squamosus naturally distributed in Turkey by using gas chromatography (GC) and GC-mass spectrometry (GC-MS). A total of sixteen fatty acids were screened in the mushroom species. The most abundant fatty acids were recorded as linoleic (10.35-65.69%), oleic (12.03-53.27%), palmitic (12.68-21.16%), stearic (2.39-4.36%) and palmitoleic (1.40-4.26%) acids in all studied mushrooms. The amounts of unsaturated fatty acids (UFAs) (60.02-80.70%) were calculated higher than saturated fatty acids (SFAs) (19.24-39.58%). The correlations or differences of the mushroom species with regard to fatty acid compositions were chemometrically investigated by using principal component analysis (PCA) and hierarchical clustering analysis (HCA). H. rubiginosa was separated with the highest amount of linoleic acid (65.69%) from other four mushroom species in both analyses.

Mushroom Supplementation in Promoting Health and Performance of Poultry: Review

This review paper aims to update and discuss the latest data available with respect to the effects of mushrooms in promoting the health and performance of broiler and layer chickens. Most studies proved that different preparations of mushrooms from diverse mushroom species improved feed utilization efficiency, growth rate, egg production, and quality traits. Mushroom supplementation decreased the count of pathogenic bacteria ( Clostridium spp., Coliforms, and E.coli and increased that of beneficial ones ( Lactobacillus spp. and Bifidobacterium) in both broiler and layer chickens. Inclusion of different preparations (powders, extracts, leftovers, etc.) of mushrooms resulted in lower cholesterol and other lipid metabolites in poultry meat and eggs. Some studies reported no significant effect of mushroom on the performance of broiler and layer chickens, however, it is concluded that mushrooms, in various forms, could be included in poultry diets without any harmful effect on their health. Further research works are also suggested to investigate the opportunities for making mushrooms part of the compound poultry feed ingredients in countries like Ethiopia.

A New Edible Wild Mushroom Species, Panus sribuabanensis (Panaceae, Polyporales) from Northern Thailand and Its Nutritional Composition, Total Phenolic Content, and Antioxidant Activity

A new edible wild mushroom species, described herein as Panus sribuabanensis, was collected from local markets and natural forests located in northern Thailand. This species is characterized by its medium to large-sized basidiomata, broadly ellipsoid to ellipsoid-shaped basidiospores, dimitic hyphal system, and the absence of hyphal pegs. A molecular phylogenetic analysis of combined the internal transcribed spacer (ITS) and large subunit (nrLSU) of nuclear ribosomal DNA sequences supported the monophyly of P. sribuabanensis as a distinct lineage within the genus Panus. Full description, illustrations, color photographs, and a phylogenetic tree to show the placement of P. sribuabanensis are provided. The dried mushroom showed a nutritional composition within the range of 2.58%–2.67% for fat content, 27.10%–27.98% for protein, and 43.97%–44.10% for carbohydrates. The ethanolic extracts from this mushroom exhibited a total phenolic content ranging from 0.66 to 0.74 mg GAE/g dry weight (dw). Moreover, the antioxidant activities of ethanolic extracts evaluated by the 2,2-diphenyl-1-picrylhydrazyl (0.90–1.08 mg TE/g dw) and ferric reducing antioxidant power (0.93–1.08 mg TE/g dw) assays demonstrate higher activity compared to the 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) assay (0.44–0.51 mg TE/g dw). The outcomes of this study provide significant information on the nutritional value, phenolic content, and antioxidant activity potential of this new mushroom species discovered in northern Thailand.

Edible Mushrooms in The Surroundings of Bangbayang Village, Situraja, Sumedang, West Java

Bangbayang is one of the villages located in the Situraja Subdistrict, Sumedang Regency, West Java. The natural conditions around the area are very cool with various types of plants, which also make it likely to find mushrooms, especially macro mushrooms that have the potential as food ingredients, but have not been reported. This study aims to inventory macro mushrooms with the potential as food ingredients in Bangbayang Village, Situraja Subdistrict, Sumedang Regency, West Java. The research method used is exploratory, and each sample of macro mushrooms obtained is observed based on the macroscopic characteristics of its fruiting body. The results of the study obtained a total of 12 species of macro mushrooms with the potential as food ingredients, namely; Agaricus campestris, Auricularia auricula, A. cornea, Boletus edulis, Cortinarius caperatus, Filoboletus manipularis, Lentinus sajor-caju, Lepista nuda, Russula rosea, Sarcomyxa edulis, Termitomyces clypeatus, and Tricholoma fraticum.

Ethanolic Extracts of Six Cultivated Mushrooms as a Source of Bioactive Compounds

Freeze-dried stems and caps of six cultivated mushroom species, namely Agaricus bisporus (white) Agaricus bisporus (brown), Lentinula edodes, Pholiota nameko, Pleurotus eryngii and Pleurotus ostreatus were subjected to ethanolic extraction. The obtained extracts were analyzed in terms of total phenolics content, total flavonoids content and antioxidant capacity, and the results were calculated per gram of mushroom dry weight and extract dry weight. The LC–MS technique was applied to determine the profiles of phenolic acids. The amount of total phenolics in the stems (per the fruiting bodies’ dry weight) ranged from 1.09 ± 0.09 mg/g (P. ostreatus) to 4.02 ± 0.20 mg/g (the white A. bisporus), whereas in the caps it ranged from 1.49 ± 0.07 mg/g (P. nameko) to 6.22 ± 0.21 mg/g (the brown A. bisporus). The total flavonoid content in the stems (per the fruiting bodies’ dry weight) varied from 0.46 ± 0.05 mg/g (P. ostreatus) to 1.72 ± 0.02 mg/g (the brown A. bisporus), and in the caps it ranged from 0.48 ± 0.01 mg/g (P. ostreatus) to 1.93 ± 0.05 mg/g (the white A. bisporus). The antioxidant potential measured with the FRAP assay showed that the caps displayed higher activity compared to the stems. However, in the case of the DPPH assay performed on A. bisporus, this relationship was inverted. Different species contained varied concentrations of phenolic acids. P. eryngii caps contained the highest amount of 3,4-DHBA, L. edodes caps were the richest source of caffeic acid, whereas the highest amount of syringic acid was observed in L. edodes stems. The caps of P. nameko contained the highest amounts of p-coumaric and t-cinnamic acid, as well as 4-hydroxybenzaldehyde.

Формування фітопатогенного мікобіому на вегетативних органах рослин пшениці озимої

Cultivated plants, which are characterized by high resistance to phytopathogenic microorganisms, create significant selective pressure on their populations and select highly pathogenic and aggressive forms. Highly susceptible plants to such microorganisms ensure a rapid growth in the population of phytopathogenic micromycetes in agrocenoses. Cultivation of such plant groups on production crops leads to an increase in biological pollution of the agrosphere and a significant decrease in the level of biological safety. This requires increased use of chemical means of plant protection against diseases, which causes chemical pollution of agroecosystems and leads to a significant decrease in the quality of plant products through the accumulation of metabolic products of phytopathogenic microorganisms in it and a decrease in biological safety in agrocenoses. Therefore, the assessment and selection of winter wheat varieties as a factor in the regulation of the phytopathogenic mycobiome in agrocenoses is a highly relevant area of research that ensures the selection of ecologically safe varieties of cultivated plants. Cultivation of such varieties leads to a decrease in the level of biological pollution in agrocenoses and increases the quality and safety of plant products. It is known that biotic, abiotic and anthropogenic factors affect the formation of populations of microorganisms. Therefore, the formation of the mycobiome on the vegetative organs of winter wheat during the ontogenesis of plants under traditional and organic technologies was investigated. It has been proven that the meteorological conditions during the years of the study, namely: high air temperature and a significant amount of precipitation during the growing season, which was observed in 2021 and in the long dry years of 2020 and 2022, had a significant impact on the formation of the population of micromycetes in the agrocenosis of winter wheat. According to the results of our own research, the population density of micromycetes and the intensity of sporulation of mushroom species decreased during the phase of emergence into the tube using traditional cultivation technology. At the same time, during the earing phase, mushroom sporulation increases by 2–3 times. This can be explained by the homeostatic reaction of the population of micromycetes in the mycobiome of vegetative organs of winter wheat plants to the chemical pressure of applied pesticides, which can cause contamination of agrocenoses with infectious structures of pathogens and their toxic metabolites. At the same time, the population density of micromycetes, under organic cultivation technology, increased during the growing season from the tillering phase to the earing phase, depending on the soil and climatic conditions. Under the conditions of various winter wheat cultivation technologies, significant changes in the formation of micromycete populations were observed due to the influence of varietal characteristics of plants. A significantly lower frequency of occurrence of species and their intensity of sporulation was observed on the vegetative organs of the Skagen variety, compared to winter wheat plants of the Podolyanka variety. This testifies to the ability of physiological and biochemical substances of plants of various varieties of winter wheat to stimulate or restrain the development of micromycetes in the mycobiome of vegetative organs of the culture. Evaluation of the plant variety based on indicators of influence on the density, frequency of occurrence and intensity of sporulation of micromycetes will ensure a decrease in the level of biological pollution and an increase in the biosafety of plant raw materials.

Determination of psilocybin and psilocin content in multiple Psilocybe cubensis mushroom strains using liquid chromatography – tandem mass spectrometry

A method for clinical potency determination of psilocybin and psilocin in hallucinogenic mushroom species Psilocybe cubensis was developed using liquid chromatography with tandem mass spectrometry (LC-MS/MS). Five strains of dried, intact mushrooms were obtained and analyzed: Blue Meanie, Creeper, B-Plus, Texas Yellow, and Thai Cubensis. An extraction protocol was developed; this included an evaluation of sample milling technique, extraction solvents, and recovery/stability. Reversed phase chromatography on fused-core particle phases was developed for the determination of the two analytes using internal standard calibration with deuterated isotopologues of each analyte. The separation takes less than 5 min. Matrix effects were investigated by comparing signal response of calibration samples in neat solution and several mushroom matrices; no significant matrix effects were observed. The limit of detection for psilocybin was 1.5 ng/mL (1.5 pg on-column; 300 ng/g mushroom) and for psilocin was 0.15 ng/mL (0.15 pg on-column; 30 ng/g mushroom) using a Shimadzu LCMS-8050 triple quadrupole mass spectrometer. Assessment of the accuracy and precision of the method indicated percent error and RSD were <6 % at all concentration levels. Three whole, intact mushrooms from each strain were analyzed individually to obtain average content differences both between strains and between mushrooms of the same strain. From most to least potent, the study found that the average total psilocybin and psilocin concentrations for the Creeper, Blue Meanie, B+, Texas Yellow, and Thai Cubensis strains were 1.36, 1.221, 1.134, 1.103, and 0.879 % (w/w), respectively. A subset of these mushrooms was also tested in a separate non-affiliated laboratory, and the results were comparable between the two laboratories. Results from the secondary laboratory showed improved precision when multiple mushrooms were homogenized together, prior to extraction.

Protective role of Pleurotus florida against streptozotocin-induced hyperglycemia in rats: A preclinical study

Pleurotus florida (Mont.) Singer is a mushroom species known to be an antioxidant, immunomodulatory, and diuretic agent, reducing blood pressure and cholesterol. The aim of this study was to evaluate the in vivo potency of P. florida's anti-diabetic properties in rats affected by hyperglycemia induced by Streptozotocin (STZ) at 55 mg/kg (i.p.), characterized by oxidative stress impairment, and changes in insulin levels and lipid profile. After inducing hyperglycemia in the rats, they were treated with P. florida acetone and methanol extracts, orally administered for 28 days at doses of 200 mg/kg and 400 mg/kg body weight. The hyperglycemic control (DC) group showed significant increases (P < 0.05) in mean blood sugar, total cholesterol, triglycerides, low-density lipoprotein cholesterol, very low-density lipoprotein cholesterol, blood urea nitrogen, lipid hydroperoxides, and malondialdehyde, compared to the normal control (NC) group The high-density lipoprotein cholesterol, serum insulin, superoxide dismutase, catalase, glutathione disulfide, glutathione peroxidase, reduced glutathione, guaiacol peroxidase, and vitamin E and C levels showed a significant decrease (P < 0.05) in DC group, compared to the NC group. Blood glucose levels, lipid profiles, and insulin levels improved significantly after 28 days of treatment, in the group treated with glibenclamide (an oral hypoglycemic drug, used as positive control), and in the groups treated with P. florida extracts. In DC group, the treatment with P. florida was found to prevent diabetes, according to histopathological studies of the kidneys, pancreas, and liver of rats. In conclusion, this study has shown that the treatment with P. florida decreased oxidative stress and glucose levels in the blood, as well as restoring changes in lipid profiles.

ՄԱԿՐՈՍԿՈՊԻԿ ՍՆԿԵՐԻ ԿԻՐԱՌՄԱՆ ՀԵՌԱՆԿԱՐՆԵՐԸ ԿՈՍՄԵՏՈԼՈԳԻԱՅՈՒՄ/PERSPECTIVES OF USAGE OF MACROFUNGI IN COSMETOLOGY

Macroscopic fungi, or macromycetes, which belong to the phylum Basidiomycota (class Agaricomycetes) and phylum Ascomycota (class Pezizomycetes), are well-known for their high nutritional value and pharmacological properties. Mycelium and fruiting bodies of wild and cultivated edible and medicinal mushrooms, as natural source of bioactive compounds (β-glucans, terpenoids, phenolics, alkaloids, thiamine, riboflavin, niacin, proteins, melanin, selenium, etc.) with medicinal and cosmetic effects (antiinflammatory, immunomodulatory, antimicrobial, antioxidant, anti-radiation, regenerating, moisturizing, nourishing, etc.) are widely used to develop various biotech products. Presently, edible and medicinal mushrooms from different taxonomic and ecological groups are of great interest in the production of anti-aging cosmetic products. Currently, 19 species of mushrooms , as potential source of cosmetic bioingredients were identified in the territory of Armenia. The study of mushroom resources, the creation and storage of pure cultures of mushroom collections open up wide opportunities for their biotechnological cultivation and the development of mycocosmetology in Armenia.